Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries
ABSTRACT Objective To characterize high-risk human papillomavirus (HPV) infections in a sample of women in two small English-speaking Caribbean countries: Saint Kitts and Nevis and Saint Vincent and the Grenadines. Methods Sexually active women ≥ 30 years old attending primary care health facilities...
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Pan American Health Organization
2017
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ftdoajarticles:oai:doaj.org/article:7cf558dbc63647a1b5a53250ddfe6939 2023-05-15T15:16:06+02:00 Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries Glennis Andall-Brereton Eulynis Brown Sherian Slater Yvette Holder Silvana Luciani Merle Lewis Beryl Irons 2017-06-01T00:00:00Z https://doaj.org/article/7cf558dbc63647a1b5a53250ddfe6939 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892017000100220&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/7cf558dbc63647a1b5a53250ddfe6939 Revista Panamericana de Salud Pública, Vol 41, Iss 0 (2017) Papilloma prevalence uterine cervical diseases Caribbean Region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2017 ftdoajarticles 2022-12-31T10:47:37Z ABSTRACT Objective To characterize high-risk human papillomavirus (HPV) infections in a sample of women in two small English-speaking Caribbean countries: Saint Kitts and Nevis and Saint Vincent and the Grenadines. Methods Sexually active women ≥ 30 years old attending primary care health facilities participated in the study. Each participant had a gynecological examination, and two cervical specimens were collected: (1) a specimen for a Papanicolaou (Pap) test and (2) a sample of exfoliated cervical cells for HPV DNA testing, using the HPV High Risk Screen Real-TM (Sacace). High-risk HPV genotypes were assessed in 404 women in Saint Kitts and Nevis and 368 women in Saint Vincent and the Grenadines. Results High-risk HPV was detected in 102 of 404 (25.2%) in Saint Kitts and Nevis and in 109 of 368 (29.6%) in Saint Vincent and the Grenadines. High-risk HPV genotypes 52, 35, 51, 45, and 31 were the most common high-risk types in Saint Kitts and Nevis. In Saint Vincent and the Grenadines, the most common high-risk HPV genotypes were 45, 35, 31, 18, and 51. Current age was found to be significantly associated with high-risk HPV infection in both countries. In addition, in Saint Vincent and the Grenadines, high parity (> 3 pregnancies) and having had an abnormal Pap smear were found to be independent risk factors for high-risk HPV. Conclusions These results contribute to the evidence on HPV prevalence for small island states of the Caribbean and support the accelerated introduction of the 9-valent HPV vaccine in the two countries and elsewhere in the English-speaking Caribbean. Use of the study’s results to guide the development of policy regarding implementation of HPV testing as the primary screening modality for older women is recommended. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Saint-Vincent ENVELOPE(-59.515,-59.515,50.600,50.600) |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
Papilloma prevalence uterine cervical diseases Caribbean Region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Papilloma prevalence uterine cervical diseases Caribbean Region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Glennis Andall-Brereton Eulynis Brown Sherian Slater Yvette Holder Silvana Luciani Merle Lewis Beryl Irons Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
topic_facet |
Papilloma prevalence uterine cervical diseases Caribbean Region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
ABSTRACT Objective To characterize high-risk human papillomavirus (HPV) infections in a sample of women in two small English-speaking Caribbean countries: Saint Kitts and Nevis and Saint Vincent and the Grenadines. Methods Sexually active women ≥ 30 years old attending primary care health facilities participated in the study. Each participant had a gynecological examination, and two cervical specimens were collected: (1) a specimen for a Papanicolaou (Pap) test and (2) a sample of exfoliated cervical cells for HPV DNA testing, using the HPV High Risk Screen Real-TM (Sacace). High-risk HPV genotypes were assessed in 404 women in Saint Kitts and Nevis and 368 women in Saint Vincent and the Grenadines. Results High-risk HPV was detected in 102 of 404 (25.2%) in Saint Kitts and Nevis and in 109 of 368 (29.6%) in Saint Vincent and the Grenadines. High-risk HPV genotypes 52, 35, 51, 45, and 31 were the most common high-risk types in Saint Kitts and Nevis. In Saint Vincent and the Grenadines, the most common high-risk HPV genotypes were 45, 35, 31, 18, and 51. Current age was found to be significantly associated with high-risk HPV infection in both countries. In addition, in Saint Vincent and the Grenadines, high parity (> 3 pregnancies) and having had an abnormal Pap smear were found to be independent risk factors for high-risk HPV. Conclusions These results contribute to the evidence on HPV prevalence for small island states of the Caribbean and support the accelerated introduction of the 9-valent HPV vaccine in the two countries and elsewhere in the English-speaking Caribbean. Use of the study’s results to guide the development of policy regarding implementation of HPV testing as the primary screening modality for older women is recommended. |
format |
Article in Journal/Newspaper |
author |
Glennis Andall-Brereton Eulynis Brown Sherian Slater Yvette Holder Silvana Luciani Merle Lewis Beryl Irons |
author_facet |
Glennis Andall-Brereton Eulynis Brown Sherian Slater Yvette Holder Silvana Luciani Merle Lewis Beryl Irons |
author_sort |
Glennis Andall-Brereton |
title |
Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
title_short |
Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
title_full |
Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
title_fullStr |
Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
title_full_unstemmed |
Prevalence of high-risk human papillomavirus among women in two English-speaking Caribbean countries |
title_sort |
prevalence of high-risk human papillomavirus among women in two english-speaking caribbean countries |
publisher |
Pan American Health Organization |
publishDate |
2017 |
url |
https://doaj.org/article/7cf558dbc63647a1b5a53250ddfe6939 |
long_lat |
ENVELOPE(-59.515,-59.515,50.600,50.600) |
geographic |
Arctic Saint-Vincent |
geographic_facet |
Arctic Saint-Vincent |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 41, Iss 0 (2017) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892017000100220&lng=en&tlng=en https://doaj.org/toc/1680-5348 1680-5348 https://doaj.org/article/7cf558dbc63647a1b5a53250ddfe6939 |
_version_ |
1766346414086946816 |