Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review
Abstract Background Schistosomiasis is still a public health issue in certain areas of developing countries (especially in sub-saharan Africa). Schistosoma haematobium is a proven carcinogenic agent that causes mainly bladder squamous cell carcinoma. This type of cancer has characteristic epidemiolo...
Published in: | Tropical Diseases, Travel Medicine and Vaccines |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2022
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s40794-022-00161-x https://doaj.org/article/7c8b0a8419934adc96f6198beedb724f |
id |
ftdoajarticles:oai:doaj.org/article:7c8b0a8419934adc96f6198beedb724f |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:7c8b0a8419934adc96f6198beedb724f 2023-05-15T15:07:18+02:00 Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review Boubacar Efared Aïchatou Balaraba Abani Bako Boubacar Idrissa Daouda Alhousseini Habiba Salifou Boureima Haboubacar Chaibou Sodé Hassan Nouhou 2022-02-01T00:00:00Z https://doi.org/10.1186/s40794-022-00161-x https://doaj.org/article/7c8b0a8419934adc96f6198beedb724f EN eng BMC https://doi.org/10.1186/s40794-022-00161-x https://doaj.org/toc/2055-0936 doi:10.1186/s40794-022-00161-x 2055-0936 https://doaj.org/article/7c8b0a8419934adc96f6198beedb724f Tropical Diseases, Travel Medicine and Vaccines, Vol 8, Iss 1, Pp 1-5 (2022) Schistosomiasis Bladder cancer Squamous cell carcinoma Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.1186/s40794-022-00161-x 2022-12-31T13:47:34Z Abstract Background Schistosomiasis is still a public health issue in certain areas of developing countries (especially in sub-saharan Africa). Schistosoma haematobium is a proven carcinogenic agent that causes mainly bladder squamous cell carcinoma. This type of cancer has characteristic epidemiological, clinical and histopathological features with poor prognosis as compared to other urinary bladder cancers not associated with this parasite. Cases presentation We report two fatal cases of advanced-stage bladder squamous cell carcinoma associated with Schistosoma haematobium in a sub-saharan developing African country (Niger), illustrating the devastating complications of this tropical neglected disease. The two cases were a 38-year-old woman and a 37-year-old male. They presented with chronic pelvic pain and hematuria. The clinical and radiological work-up revealed invasive urivary bladder tumor extended to the pelvis, that was histopathologically proven to be an invasive squamous cell carcinoma associated with Schistosoma haematobium. The two patients died shortly after the diagnosis before chemotherapy prescription. Conclusion Schistosoma-associated bladder squamous cell carcinoma has characteristic features with dismal prognosis. Eradication of this parasite remains the only efficient way to prevent the devastating consequences of this particular cancer. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Diseases, Travel Medicine and Vaccines 8 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Schistosomiasis Bladder cancer Squamous cell carcinoma Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Schistosomiasis Bladder cancer Squamous cell carcinoma Arctic medicine. Tropical medicine RC955-962 Boubacar Efared Aïchatou Balaraba Abani Bako Boubacar Idrissa Daouda Alhousseini Habiba Salifou Boureima Haboubacar Chaibou Sodé Hassan Nouhou Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
topic_facet |
Schistosomiasis Bladder cancer Squamous cell carcinoma Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Schistosomiasis is still a public health issue in certain areas of developing countries (especially in sub-saharan Africa). Schistosoma haematobium is a proven carcinogenic agent that causes mainly bladder squamous cell carcinoma. This type of cancer has characteristic epidemiological, clinical and histopathological features with poor prognosis as compared to other urinary bladder cancers not associated with this parasite. Cases presentation We report two fatal cases of advanced-stage bladder squamous cell carcinoma associated with Schistosoma haematobium in a sub-saharan developing African country (Niger), illustrating the devastating complications of this tropical neglected disease. The two cases were a 38-year-old woman and a 37-year-old male. They presented with chronic pelvic pain and hematuria. The clinical and radiological work-up revealed invasive urivary bladder tumor extended to the pelvis, that was histopathologically proven to be an invasive squamous cell carcinoma associated with Schistosoma haematobium. The two patients died shortly after the diagnosis before chemotherapy prescription. Conclusion Schistosoma-associated bladder squamous cell carcinoma has characteristic features with dismal prognosis. Eradication of this parasite remains the only efficient way to prevent the devastating consequences of this particular cancer. |
format |
Article in Journal/Newspaper |
author |
Boubacar Efared Aïchatou Balaraba Abani Bako Boubacar Idrissa Daouda Alhousseini Habiba Salifou Boureima Haboubacar Chaibou Sodé Hassan Nouhou |
author_facet |
Boubacar Efared Aïchatou Balaraba Abani Bako Boubacar Idrissa Daouda Alhousseini Habiba Salifou Boureima Haboubacar Chaibou Sodé Hassan Nouhou |
author_sort |
Boubacar Efared |
title |
Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
title_short |
Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
title_full |
Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
title_fullStr |
Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
title_full_unstemmed |
Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
title_sort |
urinary bladder schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s40794-022-00161-x https://doaj.org/article/7c8b0a8419934adc96f6198beedb724f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Diseases, Travel Medicine and Vaccines, Vol 8, Iss 1, Pp 1-5 (2022) |
op_relation |
https://doi.org/10.1186/s40794-022-00161-x https://doaj.org/toc/2055-0936 doi:10.1186/s40794-022-00161-x 2055-0936 https://doaj.org/article/7c8b0a8419934adc96f6198beedb724f |
op_doi |
https://doi.org/10.1186/s40794-022-00161-x |
container_title |
Tropical Diseases, Travel Medicine and Vaccines |
container_volume |
8 |
container_issue |
1 |
_version_ |
1766338841372786688 |