Biochemical and Metabolomic Responses of Antarctic Bacterium Planococcus sp. O5 Induced by Copper Ion

Heavy metal pollution in the Antarctic has gone beyond our imagination. Copper toxicity is a selective pressure on Planococcus sp. O5. We observed relatively broad tolerance in the polar bacterium. The heavy metal resistance pattern is Pb 2+ > Cu 2+ > Cd 2+ > Hg 2+ > Zn 2+ . In the study...

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Bibliographic Details
Published in:Toxics
Main Authors: Ziyi Cheng, Cuijuan Shi, Xiujun Gao, Xiaofei Wang, Guangfeng Kan
Format: Article in Journal/Newspaper
Language:English
Published: MDPI AG 2022
Subjects:
Antarctic strain
copper stress
adaption responses
metabolomics
Chemical technology
TP1-1185
Antarctic
The Antarctic
Antarc*
Online Access:https://doi.org/10.3390/toxics10060302
https://doaj.org/article/7c8873a337444bb6a152ea200b5bc59d
Description
Summary:Heavy metal pollution in the Antarctic has gone beyond our imagination. Copper toxicity is a selective pressure on Planococcus sp. O5. We observed relatively broad tolerance in the polar bacterium. The heavy metal resistance pattern is Pb 2+ > Cu 2+ > Cd 2+ > Hg 2+ > Zn 2+ . In the study, we combined biochemical and metabolomics approaches to investigate the Cu 2+ adaptation mechanisms of the Antarctic bacterium. Biochemical analysis revealed that copper treatment elevated the activity of antioxidants and enzymes, maintaining the bacterial redox state balance and normal cell division and growth. Metabolomics analysis demonstrated that fatty acids, amino acids, and carbohydrates played dominant roles in copper stress adaptation. The findings suggested that the adaptive mechanisms of strain O5 to copper stress included protein synthesis and repair, accumulation of organic permeable substances, up-regulation of energy metabolism, and the formation of fatty acids.

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