A comparison of DNA sequencing and the hydrolysis probe analysis (TaqMan assay) for knockdown resistance ( kdr ) mutations in Anopheles gambiae from the Republic of the Congo

• Published in: Malaria Journal
• Main Authors: Coetzee Maureen, Spillings Belinda L, Choi Kwang, Hunt Richard H, Koekemoer Lizette L
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2010
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Noire; Pointe Noire
• Online Access: https://doi.org/10.1186/1475-2875-9-278; https://doaj.org/article/7b9609f5e50a410e9cfb82c886a28573

Abstract Background Knockdown resistance ( kdr ) caused by a single base pair mutation in the sodium channel gene is strongly associated with pyrethroid insecticide resistance in Anopheles gambiae in West-Central Africa. Recently, various molecular techniques have been developed to screen for the pr...