Immunological Aspects of Isolation and Confinement
Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general. A number of stress factors, including a prolonged confinemen...
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Online Access: | https://doi.org/10.3389/fimmu.2021.697435 https://doaj.org/article/7ae7d5b1014a47608fbb41335980d08c |
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ftdoajarticles:oai:doaj.org/article:7ae7d5b1014a47608fbb41335980d08c 2023-05-15T13:55:46+02:00 Immunological Aspects of Isolation and Confinement Sergey Ponomarev Sergey Kalinin Anastasiya Sadova Marina Rykova Kseniya Orlova Brian Crucian 2021-06-01T00:00:00Z https://doi.org/10.3389/fimmu.2021.697435 https://doaj.org/article/7ae7d5b1014a47608fbb41335980d08c EN eng Frontiers Media S.A. https://www.frontiersin.org/articles/10.3389/fimmu.2021.697435/full https://doaj.org/toc/1664-3224 1664-3224 doi:10.3389/fimmu.2021.697435 https://doaj.org/article/7ae7d5b1014a47608fbb41335980d08c Frontiers in Immunology, Vol 12 (2021) adaptive immunity space flight innate immunity ground-based analogues immunology of confinement Immunologic diseases. Allergy RC581-607 article 2021 ftdoajarticles https://doi.org/10.3389/fimmu.2021.697435 2022-12-31T09:15:50Z Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general. A number of stress factors, including a prolonged confinement in a limited hermetically sealed space, influence the human body in space on board the spaceship and during the orbital flight. All these factors predominantly negatively affect various functional systems of the organism, in particular, the astronaut’s immunity. These ground-based experiments allow to elucidate the effect of confinement in a limited space on both the activation of the immunity and the changes of the immune status in dynamics. Also, due to simulation of one or another emergency situation, such an approach allows the estimation of the influence of an additional psychological stress on the immunity, particularly, in the context of the reserve capacity of the immune system. A sealed chamber seems a convenient site for working out the additional techniques for crew members selection, as well as the countermeasures for negative changes in the astronauts’ immune status. In this review we attempted to collect information describing changes in human immunity during isolation experiments with different conditions including short- and long-term experiments in hermetically closed chambers with artificial environment and during Antarctic winter-over. Article in Journal/Newspaper Antarc* Antarctic Directory of Open Access Journals: DOAJ Articles Antarctic Frontiers in Immunology 12 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
adaptive immunity space flight innate immunity ground-based analogues immunology of confinement Immunologic diseases. Allergy RC581-607 |
spellingShingle |
adaptive immunity space flight innate immunity ground-based analogues immunology of confinement Immunologic diseases. Allergy RC581-607 Sergey Ponomarev Sergey Kalinin Anastasiya Sadova Marina Rykova Kseniya Orlova Brian Crucian Immunological Aspects of Isolation and Confinement |
topic_facet |
adaptive immunity space flight innate immunity ground-based analogues immunology of confinement Immunologic diseases. Allergy RC581-607 |
description |
Beyond all doubts, the exploration of outer space is a strategically important and priority sector of the national economy, scientific and technological development of every and particular country, and of all human civilization in general. A number of stress factors, including a prolonged confinement in a limited hermetically sealed space, influence the human body in space on board the spaceship and during the orbital flight. All these factors predominantly negatively affect various functional systems of the organism, in particular, the astronaut’s immunity. These ground-based experiments allow to elucidate the effect of confinement in a limited space on both the activation of the immunity and the changes of the immune status in dynamics. Also, due to simulation of one or another emergency situation, such an approach allows the estimation of the influence of an additional psychological stress on the immunity, particularly, in the context of the reserve capacity of the immune system. A sealed chamber seems a convenient site for working out the additional techniques for crew members selection, as well as the countermeasures for negative changes in the astronauts’ immune status. In this review we attempted to collect information describing changes in human immunity during isolation experiments with different conditions including short- and long-term experiments in hermetically closed chambers with artificial environment and during Antarctic winter-over. |
format |
Article in Journal/Newspaper |
author |
Sergey Ponomarev Sergey Kalinin Anastasiya Sadova Marina Rykova Kseniya Orlova Brian Crucian |
author_facet |
Sergey Ponomarev Sergey Kalinin Anastasiya Sadova Marina Rykova Kseniya Orlova Brian Crucian |
author_sort |
Sergey Ponomarev |
title |
Immunological Aspects of Isolation and Confinement |
title_short |
Immunological Aspects of Isolation and Confinement |
title_full |
Immunological Aspects of Isolation and Confinement |
title_fullStr |
Immunological Aspects of Isolation and Confinement |
title_full_unstemmed |
Immunological Aspects of Isolation and Confinement |
title_sort |
immunological aspects of isolation and confinement |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doi.org/10.3389/fimmu.2021.697435 https://doaj.org/article/7ae7d5b1014a47608fbb41335980d08c |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_source |
Frontiers in Immunology, Vol 12 (2021) |
op_relation |
https://www.frontiersin.org/articles/10.3389/fimmu.2021.697435/full https://doaj.org/toc/1664-3224 1664-3224 doi:10.3389/fimmu.2021.697435 https://doaj.org/article/7ae7d5b1014a47608fbb41335980d08c |
op_doi |
https://doi.org/10.3389/fimmu.2021.697435 |
container_title |
Frontiers in Immunology |
container_volume |
12 |
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1766262618732888064 |