Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume
Understanding cardiac function in developing larval fishes is crucial for assessing their physiological condition and overall health. Cardiac output measurements in transparent fish larvae and other vertebrates have long been made by analyzing videos of the beating heart, and modeling this structure...
Published in: | Frontiers in Physiology |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Frontiers Media S.A.
2017
|
Subjects: | |
Online Access: | https://doi.org/10.3389/fphys.2017.00464 https://doaj.org/article/7a7f9c96560f4862a321561ccf9641e0 |
id |
ftdoajarticles:oai:doaj.org/article:7a7f9c96560f4862a321561ccf9641e0 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:7a7f9c96560f4862a321561ccf9641e0 2023-05-15T18:06:04+02:00 Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume Prescilla Perrichon Martin Grosell Warren W. Burggren 2017-07-01T00:00:00Z https://doi.org/10.3389/fphys.2017.00464 https://doaj.org/article/7a7f9c96560f4862a321561ccf9641e0 EN eng Frontiers Media S.A. http://journal.frontiersin.org/article/10.3389/fphys.2017.00464/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2017.00464 https://doaj.org/article/7a7f9c96560f4862a321561ccf9641e0 Frontiers in Physiology, Vol 8 (2017) mahi-mahi red drum larval fish heart shape modeling ventricular volume stroke volume Physiology QP1-981 article 2017 ftdoajarticles https://doi.org/10.3389/fphys.2017.00464 2022-12-31T13:08:25Z Understanding cardiac function in developing larval fishes is crucial for assessing their physiological condition and overall health. Cardiac output measurements in transparent fish larvae and other vertebrates have long been made by analyzing videos of the beating heart, and modeling this structure using a conventional simple prolate spheroid shape model. However, the larval fish heart changes shape during early development and subsequent maturation, but no consideration has been made of the effect of different heart geometries on cardiac output estimation. The present study assessed the validity of three different heart models (the “standard” prolate spheroid model as well as a cylinder and cone tip + cylinder model) applied to digital images of complete cardiac cycles in larval mahi-mahi and red drum. The inherent error of each model was determined to allow for more precise calculation of stroke volume and cardiac output. The conventional prolate spheroid and cone tip + cylinder models yielded significantly different stroke volume values at 56 hpf in red drum and from 56 to 104 hpf in mahi. End-diastolic and stroke volumes modeled by just a simple cylinder shape were 30–50% higher compared to the conventional prolate spheroid. However, when these values of stroke volume multiplied by heart rate to calculate cardiac output, no significant differences between models emerged because of considerable variability in heart rate. Essentially, the conventional prolate spheroid shape model provides the simplest measurement with lowest variability of stroke volume and cardiac output. However, assessment of heart function—especially if stroke volume is the focus of the study—should consider larval heart shape, with different models being applied on a species-by-species and developmental stage-by-stage basis for best estimation of cardiac output. Article in Journal/Newspaper Red drum Directory of Open Access Journals: DOAJ Articles Frontiers in Physiology 8 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
mahi-mahi red drum larval fish heart shape modeling ventricular volume stroke volume Physiology QP1-981 |
spellingShingle |
mahi-mahi red drum larval fish heart shape modeling ventricular volume stroke volume Physiology QP1-981 Prescilla Perrichon Martin Grosell Warren W. Burggren Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
topic_facet |
mahi-mahi red drum larval fish heart shape modeling ventricular volume stroke volume Physiology QP1-981 |
description |
Understanding cardiac function in developing larval fishes is crucial for assessing their physiological condition and overall health. Cardiac output measurements in transparent fish larvae and other vertebrates have long been made by analyzing videos of the beating heart, and modeling this structure using a conventional simple prolate spheroid shape model. However, the larval fish heart changes shape during early development and subsequent maturation, but no consideration has been made of the effect of different heart geometries on cardiac output estimation. The present study assessed the validity of three different heart models (the “standard” prolate spheroid model as well as a cylinder and cone tip + cylinder model) applied to digital images of complete cardiac cycles in larval mahi-mahi and red drum. The inherent error of each model was determined to allow for more precise calculation of stroke volume and cardiac output. The conventional prolate spheroid and cone tip + cylinder models yielded significantly different stroke volume values at 56 hpf in red drum and from 56 to 104 hpf in mahi. End-diastolic and stroke volumes modeled by just a simple cylinder shape were 30–50% higher compared to the conventional prolate spheroid. However, when these values of stroke volume multiplied by heart rate to calculate cardiac output, no significant differences between models emerged because of considerable variability in heart rate. Essentially, the conventional prolate spheroid shape model provides the simplest measurement with lowest variability of stroke volume and cardiac output. However, assessment of heart function—especially if stroke volume is the focus of the study—should consider larval heart shape, with different models being applied on a species-by-species and developmental stage-by-stage basis for best estimation of cardiac output. |
format |
Article in Journal/Newspaper |
author |
Prescilla Perrichon Martin Grosell Warren W. Burggren |
author_facet |
Prescilla Perrichon Martin Grosell Warren W. Burggren |
author_sort |
Prescilla Perrichon |
title |
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
title_short |
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
title_full |
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
title_fullStr |
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
title_full_unstemmed |
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume |
title_sort |
heart performance determination by visualization in larval fishes: influence of alternative models for heart shape and volume |
publisher |
Frontiers Media S.A. |
publishDate |
2017 |
url |
https://doi.org/10.3389/fphys.2017.00464 https://doaj.org/article/7a7f9c96560f4862a321561ccf9641e0 |
genre |
Red drum |
genre_facet |
Red drum |
op_source |
Frontiers in Physiology, Vol 8 (2017) |
op_relation |
http://journal.frontiersin.org/article/10.3389/fphys.2017.00464/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2017.00464 https://doaj.org/article/7a7f9c96560f4862a321561ccf9641e0 |
op_doi |
https://doi.org/10.3389/fphys.2017.00464 |
container_title |
Frontiers in Physiology |
container_volume |
8 |
_version_ |
1766177634094415872 |