Measuring the burden of neglected tropical diseases: the global burden of disease framework.
Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector. Traditional sources of information about the descriptive epidemiology of diseases, injuries, and risk factor...
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ftdoajarticles:oai:doaj.org/article:7898567ce15e4244b1118fc4948d0073 2023-05-15T15:15:14+02:00 Measuring the burden of neglected tropical diseases: the global burden of disease framework. Colin D Mathers Majid Ezzati Alan D Lopez 2007-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0000114 https://doaj.org/article/7898567ce15e4244b1118fc4948d0073 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC2100367?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000114 https://doaj.org/article/7898567ce15e4244b1118fc4948d0073 PLoS Neglected Tropical Diseases, Vol 1, Iss 2, p e114 (2007) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2007 ftdoajarticles https://doi.org/10.1371/journal.pntd.0000114 2022-12-31T11:22:37Z Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector. Traditional sources of information about the descriptive epidemiology of diseases, injuries, and risk factors are generally incomplete, fragmented, and of uncertain reliability and comparability. The Global Burden of Disease (GBD) study has provided a conceptual and methodological framework to quantify and compare the health of populations using a summary measure of both mortality and disability, the disability-adjusted life year (DALY).This paper describes key features of the Global Burden of Disease analytic approach, which provides a standardized measurement framework to permit comparisons across diseases and injuries, as well as risk factors, and a systematic approach to the evaluation of data. The paper describes the evolution of the GBD, starting from the first study for the year 1990, summarizes the methodological improvements incorporated into GBD revisions for the years 2000-2004 carried out by the World Health Organization, and examines priorities and issues for the next major GBD study, funded by the Bill & Melinda Gates Foundation, and commencing in 2007.The paper presents an overview of summary results from the Global Burden of Disease study 2002, with a particular focus on the neglected tropical diseases, and also an overview of the comparative risk assessment for 26 global risk factors. Taken together, trypanosomiasis, Chagas disease, schistosomiasis, leishmaniasis, lymphatic filariasis, onchocerciasis, intestinal nematode infections, Japanese encephalitis, dengue, and leprosy accounted for an estimated 177,000 deaths worldwide in 2002, mostly in sub-Saharan Africa, and about 20 million DALYs, or 1.3% of the global burden of disease and injuries. Further research is currently underway to revise and update these estimates. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Daly ENVELOPE(63.761,63.761,-67.513,-67.513) PLoS Neglected Tropical Diseases 1 2 e114 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Colin D Mathers Majid Ezzati Alan D Lopez Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Reliable, comparable information about the main causes of disease and injury in populations, and how these are changing, is a critical input for debates about priorities in the health sector. Traditional sources of information about the descriptive epidemiology of diseases, injuries, and risk factors are generally incomplete, fragmented, and of uncertain reliability and comparability. The Global Burden of Disease (GBD) study has provided a conceptual and methodological framework to quantify and compare the health of populations using a summary measure of both mortality and disability, the disability-adjusted life year (DALY).This paper describes key features of the Global Burden of Disease analytic approach, which provides a standardized measurement framework to permit comparisons across diseases and injuries, as well as risk factors, and a systematic approach to the evaluation of data. The paper describes the evolution of the GBD, starting from the first study for the year 1990, summarizes the methodological improvements incorporated into GBD revisions for the years 2000-2004 carried out by the World Health Organization, and examines priorities and issues for the next major GBD study, funded by the Bill & Melinda Gates Foundation, and commencing in 2007.The paper presents an overview of summary results from the Global Burden of Disease study 2002, with a particular focus on the neglected tropical diseases, and also an overview of the comparative risk assessment for 26 global risk factors. Taken together, trypanosomiasis, Chagas disease, schistosomiasis, leishmaniasis, lymphatic filariasis, onchocerciasis, intestinal nematode infections, Japanese encephalitis, dengue, and leprosy accounted for an estimated 177,000 deaths worldwide in 2002, mostly in sub-Saharan Africa, and about 20 million DALYs, or 1.3% of the global burden of disease and injuries. Further research is currently underway to revise and update these estimates. |
format |
Article in Journal/Newspaper |
author |
Colin D Mathers Majid Ezzati Alan D Lopez |
author_facet |
Colin D Mathers Majid Ezzati Alan D Lopez |
author_sort |
Colin D Mathers |
title |
Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
title_short |
Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
title_full |
Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
title_fullStr |
Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
title_full_unstemmed |
Measuring the burden of neglected tropical diseases: the global burden of disease framework. |
title_sort |
measuring the burden of neglected tropical diseases: the global burden of disease framework. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2007 |
url |
https://doi.org/10.1371/journal.pntd.0000114 https://doaj.org/article/7898567ce15e4244b1118fc4948d0073 |
long_lat |
ENVELOPE(63.761,63.761,-67.513,-67.513) |
geographic |
Arctic Daly |
geographic_facet |
Arctic Daly |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 1, Iss 2, p e114 (2007) |
op_relation |
http://europepmc.org/articles/PMC2100367?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000114 https://doaj.org/article/7898567ce15e4244b1118fc4948d0073 |
op_doi |
https://doi.org/10.1371/journal.pntd.0000114 |
container_title |
PLoS Neglected Tropical Diseases |
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2 |
container_start_page |
e114 |
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