Lynch syndrome screening in colorectal and endometrial cancers in Iceland

Background and purpose: Screening for Lynch syndrome (LS) with mismatch repair (MMR) protein immunohistochemistry (IHC) in all patients with newly diagnosed colorectal (CRC) and endometrial cancer (EC) was implemented in Iceland in 2017. The aim of the study is to assess the accuracy of screening in...

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Bibliographic Details
Published in:Acta Oncologica
Main Authors: Katla R. Kluvers, Thordur Tryggvason, Vigdis Stefansdottir, Jon G. Jonasson, Petur Snaebjornsson, Sigurdis Haraldsdottir
Format: Article in Journal/Newspaper
Language:English
Published: Medical Journals Sweden 2025
Subjects:
Lynch syndrome
Cancer genetics
Mismatch repair deficiency
Founder variant
MMR immunohistochemistry
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Lynch
Iceland
Online Access:https://doi.org/10.2340/1651-226X.2025.41957
https://doaj.org/article/76f21a211bfc4fc79eebfc90bb7259fe

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