In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

Abstract Background Decreased efficacy of artemisinin-based combination therapy (ACT) for Plasmodium falciparum malaria has been previously reported in patients with sickle cell disease (SCD). The main purpose of this study was to investigate the in vitro susceptibility of isolates to dihydro-artemi...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Albert A. Gnondjui, Offianan A. Toure, Berenger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’Guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo, Ronan Jambou
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2024
Subjects:
Sickle cell anemia
Artemisinin combination therapy
Plasmodium falciparum
Anti-malarial drugs
Treatment resistance
In vitro drug monitoring
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Sickle
Online Access:https://doi.org/10.1186/s12936-023-04819-5
https://doaj.org/article/75f1c88a89f64bb7afe90c80c992ebd0

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