Canine visceral leishmaniasis in the Northeast Region of Brazil
Abstract Background Visceral leishmaniasis (VL) is a zoonosis that affects dogs and other mammals, including humans. Contact with dogs is a major risk factor for humans. This disease is endemic in several regions of Brazil. The aim of this study was to determine the prevalence of Leishmania spp. inf...
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ftdoajarticles:oai:doaj.org/article:756198bfc12b4b2daee89a45885ce40e 2023-05-15T15:09:35+02:00 Canine visceral leishmaniasis in the Northeast Region of Brazil Flávio Gonçalves Brito Helio Langoni Rodrigo Costa da Silva Tereza Emmanuelle de Farias Rotondano Marcia Almeida de Melo Giselle Souza da Paz 2016-05-01T00:00:00Z https://doi.org/10.1186/s40409-016-0069-4 https://doaj.org/article/756198bfc12b4b2daee89a45885ce40e EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100311&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-016-0069-4 https://doaj.org/article/756198bfc12b4b2daee89a45885ce40e Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 22, Iss 0 (2016) Kala-azar Diagnosis Dog Zoonosis Risk factors Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2016 ftdoajarticles https://doi.org/10.1186/s40409-016-0069-4 2022-12-31T00:44:28Z Abstract Background Visceral leishmaniasis (VL) is a zoonosis that affects dogs and other mammals, including humans. Contact with dogs is a major risk factor for humans. This disease is endemic in several regions of Brazil. The aim of this study was to determine the prevalence of Leishmania spp. infection in dogs and to correlate it with possible risk factors. Methods Blood samples were collected from 391 dogs of different ages, breeds, and both genders, coming from Campina Grande, Paraíba state, Brazil. An epidemiological questionnaire was employed in order to identify risk factors associated with the disease. Serological tests were performed using indirect immunofluorescence, enzyme-linked immunosorbent assay (ELISA S7®) and polymerase chain reaction. Results Leishmania spp. antibodies were detected in 33 (8.4 %) and 17 (4.3 %) dogs according to the indirect immunofluorescence test (IFAT) and enzyme-linked immunosorbent assay (ELISA S7®), respectively. PCR results indicated the presence of L. chagasi DNA in only eight (2 %) blood samples. There was a significant association between reactive animals and contact with animals from different houses (OR = 4.1; p= 0.02). Conclusions It is suggested that CVL may occur in urban areas. Moreover, it is demonstrated that the association among different diagnostic tests may lead to a more accurate identification of positive animals, which might help to improve the disease control and prevent euthanasia in false-positive results. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Azar ENVELOPE(-63.733,-63.733,-64.983,-64.983) Journal of Venomous Animals and Toxins including Tropical Diseases 22 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Kala-azar Diagnosis Dog Zoonosis Risk factors Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
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Kala-azar Diagnosis Dog Zoonosis Risk factors Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Flávio Gonçalves Brito Helio Langoni Rodrigo Costa da Silva Tereza Emmanuelle de Farias Rotondano Marcia Almeida de Melo Giselle Souza da Paz Canine visceral leishmaniasis in the Northeast Region of Brazil |
topic_facet |
Kala-azar Diagnosis Dog Zoonosis Risk factors Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Abstract Background Visceral leishmaniasis (VL) is a zoonosis that affects dogs and other mammals, including humans. Contact with dogs is a major risk factor for humans. This disease is endemic in several regions of Brazil. The aim of this study was to determine the prevalence of Leishmania spp. infection in dogs and to correlate it with possible risk factors. Methods Blood samples were collected from 391 dogs of different ages, breeds, and both genders, coming from Campina Grande, Paraíba state, Brazil. An epidemiological questionnaire was employed in order to identify risk factors associated with the disease. Serological tests were performed using indirect immunofluorescence, enzyme-linked immunosorbent assay (ELISA S7®) and polymerase chain reaction. Results Leishmania spp. antibodies were detected in 33 (8.4 %) and 17 (4.3 %) dogs according to the indirect immunofluorescence test (IFAT) and enzyme-linked immunosorbent assay (ELISA S7®), respectively. PCR results indicated the presence of L. chagasi DNA in only eight (2 %) blood samples. There was a significant association between reactive animals and contact with animals from different houses (OR = 4.1; p= 0.02). Conclusions It is suggested that CVL may occur in urban areas. Moreover, it is demonstrated that the association among different diagnostic tests may lead to a more accurate identification of positive animals, which might help to improve the disease control and prevent euthanasia in false-positive results. |
format |
Article in Journal/Newspaper |
author |
Flávio Gonçalves Brito Helio Langoni Rodrigo Costa da Silva Tereza Emmanuelle de Farias Rotondano Marcia Almeida de Melo Giselle Souza da Paz |
author_facet |
Flávio Gonçalves Brito Helio Langoni Rodrigo Costa da Silva Tereza Emmanuelle de Farias Rotondano Marcia Almeida de Melo Giselle Souza da Paz |
author_sort |
Flávio Gonçalves Brito |
title |
Canine visceral leishmaniasis in the Northeast Region of Brazil |
title_short |
Canine visceral leishmaniasis in the Northeast Region of Brazil |
title_full |
Canine visceral leishmaniasis in the Northeast Region of Brazil |
title_fullStr |
Canine visceral leishmaniasis in the Northeast Region of Brazil |
title_full_unstemmed |
Canine visceral leishmaniasis in the Northeast Region of Brazil |
title_sort |
canine visceral leishmaniasis in the northeast region of brazil |
publisher |
SciELO |
publishDate |
2016 |
url |
https://doi.org/10.1186/s40409-016-0069-4 https://doaj.org/article/756198bfc12b4b2daee89a45885ce40e |
long_lat |
ENVELOPE(-63.733,-63.733,-64.983,-64.983) |
geographic |
Arctic Azar |
geographic_facet |
Arctic Azar |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 22, Iss 0 (2016) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100311&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-016-0069-4 https://doaj.org/article/756198bfc12b4b2daee89a45885ce40e |
op_doi |
https://doi.org/10.1186/s40409-016-0069-4 |
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Journal of Venomous Animals and Toxins including Tropical Diseases |
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22 |
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1 |
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1766340747461656576 |