Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug
Objective: To explore the leaves of Hydrocotyle javanica Thunb. as a source of safe and effective antibacterial herbal medicine. Methods: The standardization was validated by stepwise physicochemical studies, element analysis, determination of ash values, fluorescence analysis, assessment of moistur...
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:749f839bb8ce4ced81f934158a4e011e 2023-05-15T15:09:31+02:00 Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug Manab Mandal Debabrata Misra Narendra Nath Ghosh Vivekananda Mandal 2017-11-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.10.001 https://doaj.org/article/749f839bb8ce4ced81f934158a4e011e EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117310675 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.10.001 https://doaj.org/article/749f839bb8ce4ced81f934158a4e011e Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 11, Pp 979-986 (2017) Hydrocotyle javanica Thunb Herbal drug Physico-chemical analysis Mineral and elemental compositions Heavy metals contents Biomedical significance Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.10.001 2022-12-31T13:12:19Z Objective: To explore the leaves of Hydrocotyle javanica Thunb. as a source of safe and effective antibacterial herbal medicine. Methods: The standardization was validated by stepwise physicochemical studies, element analysis, determination of ash values, fluorescence analysis, assessment of moisture content, extractive values in different solvent systems and extraction methods. Heavy metal contents, mineral and element contents were analysed by atomic absorption spectrophotometry, inductively coupled plasma-mass spectrometer and CHNS/O analyser, respectively. Results: The methanol extract of the folklore medicinal plant having antibacterial efficacy contained flavonoids and phenolic OH groups. The ICP multi standard indicated the presence of three major compounds with molecular mass of 161190 and 221 Da. Heavy metals viz. lead, mercury and copper content were 4.38 ppm, < 0.05 ppm and 24.70 ppm, respectively. Minerals content of calcium, phosphorus, potassium and iron were 1190.94 mg/100 g, 375.57 mg/100 g, 2820 mg/100 g and 340.20 mg/100 g of plant sample, respectively. Elements like carbon, hydrogen, nitrogen and sulphur contents were 38.18%, 5.67%, 2.23% and 0.51%, respectively. Heavy metal profile of the tested plant was within the permissible limits of the regulatory authorities. Conclusions: Hence the present physicochemical and elements studies reveals that the plant Hydrocotyle javanica Thunb. could be a potent source of herbal preparation as well as a safe and novel synthetic antibacterial drug. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 11 979 986 |
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Directory of Open Access Journals: DOAJ Articles |
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topic |
Hydrocotyle javanica Thunb Herbal drug Physico-chemical analysis Mineral and elemental compositions Heavy metals contents Biomedical significance Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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Hydrocotyle javanica Thunb Herbal drug Physico-chemical analysis Mineral and elemental compositions Heavy metals contents Biomedical significance Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Manab Mandal Debabrata Misra Narendra Nath Ghosh Vivekananda Mandal Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
topic_facet |
Hydrocotyle javanica Thunb Herbal drug Physico-chemical analysis Mineral and elemental compositions Heavy metals contents Biomedical significance Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To explore the leaves of Hydrocotyle javanica Thunb. as a source of safe and effective antibacterial herbal medicine. Methods: The standardization was validated by stepwise physicochemical studies, element analysis, determination of ash values, fluorescence analysis, assessment of moisture content, extractive values in different solvent systems and extraction methods. Heavy metal contents, mineral and element contents were analysed by atomic absorption spectrophotometry, inductively coupled plasma-mass spectrometer and CHNS/O analyser, respectively. Results: The methanol extract of the folklore medicinal plant having antibacterial efficacy contained flavonoids and phenolic OH groups. The ICP multi standard indicated the presence of three major compounds with molecular mass of 161190 and 221 Da. Heavy metals viz. lead, mercury and copper content were 4.38 ppm, < 0.05 ppm and 24.70 ppm, respectively. Minerals content of calcium, phosphorus, potassium and iron were 1190.94 mg/100 g, 375.57 mg/100 g, 2820 mg/100 g and 340.20 mg/100 g of plant sample, respectively. Elements like carbon, hydrogen, nitrogen and sulphur contents were 38.18%, 5.67%, 2.23% and 0.51%, respectively. Heavy metal profile of the tested plant was within the permissible limits of the regulatory authorities. Conclusions: Hence the present physicochemical and elements studies reveals that the plant Hydrocotyle javanica Thunb. could be a potent source of herbal preparation as well as a safe and novel synthetic antibacterial drug. |
format |
Article in Journal/Newspaper |
author |
Manab Mandal Debabrata Misra Narendra Nath Ghosh Vivekananda Mandal |
author_facet |
Manab Mandal Debabrata Misra Narendra Nath Ghosh Vivekananda Mandal |
author_sort |
Manab Mandal |
title |
Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
title_short |
Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
title_full |
Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
title_fullStr |
Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
title_full_unstemmed |
Physicochemical and elemental studies of Hydrocotyle javanica Thunb. for standardization as herbal drug |
title_sort |
physicochemical and elemental studies of hydrocotyle javanica thunb. for standardization as herbal drug |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.10.001 https://doaj.org/article/749f839bb8ce4ced81f934158a4e011e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 11, Pp 979-986 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117310675 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.10.001 https://doaj.org/article/749f839bb8ce4ced81f934158a4e011e |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.10.001 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
11 |
container_start_page |
979 |
op_container_end_page |
986 |
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1766340693793439744 |