Observational study of the aerobic gut microbiota

• Main Authors: Xiomara Moreno Calderón, Andris Ayroni Vialva-Guerrero, María Luisa Núñez-Bello, Carolina Macero-Estévez, Karolina Coromoto López-Barrera, Ana Cecilia Márquez-Duque, María Fátima Garcés-Da Silva
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2020
• Subjects: disbiosis; microbiota gastrointestinal; trastorno del espectro autista; enfermedades inflamatorias del intestino; enfermedades autoinmunes; hipersensibilidad; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic
• Online Access: https://doi.org/10.5281/zenodo.4053038; https://doaj.org/article/7483d0da17214d80916208a83d966968

The microbial ecosystem associated with the intestine is the most diverse and complex in the human being, since it changes during the different stages of life. Losing balance of this intestinal ecosystem is known as dysbiosis. To establish the possible relationship between aerobic dysbiosis and diseases of clinical interest found. Three hundred and seventy-seven (377) cases of dysbiosis with different pathologies such as autism spectrum disorder (ASD), inflammatory bowel disease, allergies, food intolerance, among others; and a control group of 497 apparently healthy people, were studied. For the analysis of the information, multinomial logistic regression and Student's t tests were used, adjusted to a 95% confidence interval. The growth of beneficial microbiota showed variability in the dysbiosis case group compared to the control group (p <0.001). The transient microbiota causing dysbiosis was mainly made up of gram-positive cocci: Streptococcus viridans group, Enterococcus faecium and Enterococcus gallinarum; gram-negative bacilli: Klebsiella pneumoniae, Enterobacter cloacae complex, and Klebsiella oxytoca and Candida albicans, Candida tropicalis and Candida parapsilosis complex species. The most susceptible population with dysbiosis was children aged between 2 and 6 years. The ASD and food intolerance were significantly associated with dysbiosis (p <0.05).