Psychiatric research in the Northern Finland Birth Cohort 1986 – a systematic review

The Northern Finland Birth Cohort 1986 is a large population-based birth cohort, which aims to promote health and wellbeing of the population. In this paper, we systematically review the psychiatric research performed in the cohort until today, i.e. at the age of 32 years of the cohort (2018). We co...

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Bibliographic Details
Published in:International Journal of Circumpolar Health
Main Authors: Jouko Miettunen, Marianne Haapea, Lassi Björnholm, Sanna Huhtaniska, Teija Juola, Lotta Kinnunen, Heli Lehtiniemi, Johannes Lieslehto, Nina Rautio, Tanja Nordström
Format: Article in Journal/Newspaper
Language:English
Published: Taylor & Francis Group 2019
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Online Access:https://doi.org/10.1080/22423982.2019.1571382
https://doaj.org/article/7380432a33f54957a62269f7b0a39b53
Description
Summary:The Northern Finland Birth Cohort 1986 is a large population-based birth cohort, which aims to promote health and wellbeing of the population. In this paper, we systematically review the psychiatric research performed in the cohort until today, i.e. at the age of 32 years of the cohort (2018). We conducted a systematic literature search using the databases of PubMed and Scopus and complemented it with a manual search. We found a total of 94 articles, which were classified as examining ADHD, emotional and behavioural problems, psychosis risk or other studies relating to psychiatric subjects. The articles are mainly based on two large comprehensive follow-up studies of the cohort and several substudies. The studies have often used also nationwide register data. The studies have found several early predictors for the aforementioned psychiatric outcomes, such as problems at pregnancy and birth, family factors in childhood, physical inactivity and substance use in adolescence. There are also novel findings relating to brain imaging and cognition, for instance regarding familial risk of psychosis in relation to resting state functional MRI. The Northern Finland Birth Cohort 1986 has been utilised frequently in psychiatric research and future data collections are likely to lead to new scientifically important findings. Abbreviations: attention deficit hyperactivity disorder (ADHD); magnetic resonance imaging (MRI)