Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004
INTRODUCTION: To review measles IgM-positive cases of febrile rash illnesses in the State of São Paulo, Brazil, over the five-year period following interruption of measles virus transmission. METHODS: We reviewed 463 measles IgM-positive cases of febrile rash illness in the State of São Paulo, from...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2010
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ftdoajarticles:oai:doaj.org/article:72f47e4b8e034ebdb83ca6c7c5b2c73d 2023-05-15T15:18:48+02:00 Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 Flávia Helena Ciccone Telma Regina Marques Pinto Carvalhanas Ana Maria Sardinha Afonso Brendan Flannery Eliseu Alves Waldman 2010-06-01T00:00:00Z https://doi.org/10.1590/S0037-86822010000300004 https://doaj.org/article/72f47e4b8e034ebdb83ca6c7c5b2c73d EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000300004 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822010000300004 0037-8682 1678-9849 https://doaj.org/article/72f47e4b8e034ebdb83ca6c7c5b2c73d Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 3, Pp 234-239 (2010) Sarampo Vigilância por síndrome Doença exantemática Measles Syndromic surveillance Rash illness Arctic medicine. Tropical medicine RC955-962 article 2010 ftdoajarticles https://doi.org/10.1590/S0037-86822010000300004 2022-12-30T21:27:05Z INTRODUCTION: To review measles IgM-positive cases of febrile rash illnesses in the State of São Paulo, Brazil, over the five-year period following interruption of measles virus transmission. METHODS: We reviewed 463 measles IgM-positive cases of febrile rash illness in the State of São Paulo, from 2000 to 2004. Individuals vaccinated against measles < 56 days prior to specimen collection were considered to be exposed to the vaccine. Serum from the acute and convalescent phases was tested for evidence of measles, rubella, parvovirus B19 and human herpes virus-6 infection. In the absence of seroconversion to measles immunoglobulin-G, measles IgM-positive cases were considered false positives in individuals with evidence of other viral infections. RESULTS: Among the 463 individuals with febrile rash illness who tested positive for measles IgM antibodies during the period, 297 (64%) were classified as exposed to the vaccine. Among the 166 cases that were not exposed to the vaccine, 109 (66%) were considered false positives based on the absence of seroconversion, among which 21 (13%) had evidence of rubella virus infection, 49 (30%) parvovirus B19 and 28 (17%) human herpes virus-6 infection. CONCLUSIONS: Following the interruption of measles virus transmission, thorough investigation of measles IgM-positive cases is required, especially among cases not exposed to the vaccine. Laboratory testing for etiologies of febrile rash illness aids interpretation of these cases. INTRODUÇÃO: Revisar os casos de doenças febris exantemáticas com IgM reagente contra o sarampo, no Estado de São Paulo, Brasil, durante os cinco anos seguidos a interrupção da transmissão do vírus do sarampo. MÉTODOS: Nós revisamos 463 casos de doenças febris exantemáticas com IgM reagente contra o sarampo, no Estado de São Paulo, Brasil, de 2000 a 2004. Indivíduos vacinados contra o sarampo 56 dias antes da coleta de amostra foram considerados expostos à vacina. Soros da fase aguda e de convalescença foram testados para a evidência de infecção de ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Aguda ENVELOPE(-26.750,-26.750,-76.150,-76.150) Arctic Revista da Sociedade Brasileira de Medicina Tropical 43 3 234 239 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
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Sarampo Vigilância por síndrome Doença exantemática Measles Syndromic surveillance Rash illness Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Sarampo Vigilância por síndrome Doença exantemática Measles Syndromic surveillance Rash illness Arctic medicine. Tropical medicine RC955-962 Flávia Helena Ciccone Telma Regina Marques Pinto Carvalhanas Ana Maria Sardinha Afonso Brendan Flannery Eliseu Alves Waldman Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
topic_facet |
Sarampo Vigilância por síndrome Doença exantemática Measles Syndromic surveillance Rash illness Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: To review measles IgM-positive cases of febrile rash illnesses in the State of São Paulo, Brazil, over the five-year period following interruption of measles virus transmission. METHODS: We reviewed 463 measles IgM-positive cases of febrile rash illness in the State of São Paulo, from 2000 to 2004. Individuals vaccinated against measles < 56 days prior to specimen collection were considered to be exposed to the vaccine. Serum from the acute and convalescent phases was tested for evidence of measles, rubella, parvovirus B19 and human herpes virus-6 infection. In the absence of seroconversion to measles immunoglobulin-G, measles IgM-positive cases were considered false positives in individuals with evidence of other viral infections. RESULTS: Among the 463 individuals with febrile rash illness who tested positive for measles IgM antibodies during the period, 297 (64%) were classified as exposed to the vaccine. Among the 166 cases that were not exposed to the vaccine, 109 (66%) were considered false positives based on the absence of seroconversion, among which 21 (13%) had evidence of rubella virus infection, 49 (30%) parvovirus B19 and 28 (17%) human herpes virus-6 infection. CONCLUSIONS: Following the interruption of measles virus transmission, thorough investigation of measles IgM-positive cases is required, especially among cases not exposed to the vaccine. Laboratory testing for etiologies of febrile rash illness aids interpretation of these cases. INTRODUÇÃO: Revisar os casos de doenças febris exantemáticas com IgM reagente contra o sarampo, no Estado de São Paulo, Brasil, durante os cinco anos seguidos a interrupção da transmissão do vírus do sarampo. MÉTODOS: Nós revisamos 463 casos de doenças febris exantemáticas com IgM reagente contra o sarampo, no Estado de São Paulo, Brasil, de 2000 a 2004. Indivíduos vacinados contra o sarampo 56 dias antes da coleta de amostra foram considerados expostos à vacina. Soros da fase aguda e de convalescença foram testados para a evidência de infecção de ... |
format |
Article in Journal/Newspaper |
author |
Flávia Helena Ciccone Telma Regina Marques Pinto Carvalhanas Ana Maria Sardinha Afonso Brendan Flannery Eliseu Alves Waldman |
author_facet |
Flávia Helena Ciccone Telma Regina Marques Pinto Carvalhanas Ana Maria Sardinha Afonso Brendan Flannery Eliseu Alves Waldman |
author_sort |
Flávia Helena Ciccone |
title |
Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
title_short |
Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
title_full |
Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
title_fullStr |
Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
title_full_unstemmed |
Investigation of measles IgM-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, State of São Paulo, Brazil, 2000-2004 Investigação dos casos de doenças febris exantemáticas com IgM reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, Estado de São Paulo, 2000-2004 |
title_sort |
investigation of measles igm-seropositive cases of febrile rash illnesses in the absence of documented measles virus transmission, state of são paulo, brazil, 2000-2004 investigação dos casos de doenças febris exantemáticas com igm reagente contra o sarampo na ausência de transmissão documentada do vírus do sarampo, estado de são paulo, 2000-2004 |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2010 |
url |
https://doi.org/10.1590/S0037-86822010000300004 https://doaj.org/article/72f47e4b8e034ebdb83ca6c7c5b2c73d |
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ENVELOPE(-26.750,-26.750,-76.150,-76.150) |
geographic |
Aguda Arctic |
geographic_facet |
Aguda Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 43, Iss 3, Pp 234-239 (2010) |
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822010000300004 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822010000300004 0037-8682 1678-9849 https://doaj.org/article/72f47e4b8e034ebdb83ca6c7c5b2c73d |
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https://doi.org/10.1590/S0037-86822010000300004 |
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