Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients
Cryptosporidium spp. and Cystoisospora belli are monoxenic protozoa that have been recognized as the causative agents of chronic diarrhea in immunocompromised individuals, especially HIV-infected subjects. The objective of this study was to evaluate the frequency of these intestinal protozoa in HIV-...
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ftdoajarticles:oai:doaj.org/article:72ce178469684bd5943985296c2a465c 2024-09-09T19:26:32+00:00 Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients Dnieber Chagas Assis Deisy Vivian Resende Marlene Cabrine-Santos Dalmo Correia Márcia Benedita Oliveira-Silva 2013-06-01T00:00:00Z https://doi.org/10.1590/S0036-46652013000300002 https://doaj.org/article/72ce178469684bd5943985296c2a465c EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000300149&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652013000300002 https://doaj.org/article/72ce178469684bd5943985296c2a465c Revista do Instituto de Medicina Tropical de São Paulo, Vol 55, Iss 3, Pp 149-154 (2013) Cryptosporidium spp Cystoisospora belli Genetic characterization HIV Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2013 ftdoajarticles https://doi.org/10.1590/S0036-46652013000300002 2024-08-05T17:49:30Z Cryptosporidium spp. and Cystoisospora belli are monoxenic protozoa that have been recognized as the causative agents of chronic diarrhea in immunocompromised individuals, especially HIV-infected subjects. The objective of this study was to evaluate the frequency of these intestinal protozoa in HIV-positive patients in the Triângulo Mineiro region of Brazil and to correlate the presence of these infections with clinical, epidemiological and laboratory data of the patients. Oocysts were detected in stool samples of 10 (16.9%) of the 59 patients studied, while Cryptosporidium spp. were present in 10.1% (6/59) and C. belli in 6.7% (4/59). The frequency of these parasites was higher among patients with diarrheic syndrome and CD4+ T lymphocyte counts < 200 cells/mm 3 , demonstrating the opportunistic characteristic of these infections. A significant association was observed between the lack of adherence to antiretroviral therapy and the presence of Cryptosporidium spp. and/or C. belli. Parasitism with Cryptosporidium spp. was more frequent in February and April, the months following the period of high rainfall. The same was not observed for C. belli. Genetic characterization of two isolates led to the identification of Cryptosporidium parvum, one of the main species associated with the zoonotic transmission of cryptosporidiosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 55 3 149 154 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Cryptosporidium spp Cystoisospora belli Genetic characterization HIV Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Cryptosporidium spp Cystoisospora belli Genetic characterization HIV Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Dnieber Chagas Assis Deisy Vivian Resende Marlene Cabrine-Santos Dalmo Correia Márcia Benedita Oliveira-Silva Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
topic_facet |
Cryptosporidium spp Cystoisospora belli Genetic characterization HIV Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Cryptosporidium spp. and Cystoisospora belli are monoxenic protozoa that have been recognized as the causative agents of chronic diarrhea in immunocompromised individuals, especially HIV-infected subjects. The objective of this study was to evaluate the frequency of these intestinal protozoa in HIV-positive patients in the Triângulo Mineiro region of Brazil and to correlate the presence of these infections with clinical, epidemiological and laboratory data of the patients. Oocysts were detected in stool samples of 10 (16.9%) of the 59 patients studied, while Cryptosporidium spp. were present in 10.1% (6/59) and C. belli in 6.7% (4/59). The frequency of these parasites was higher among patients with diarrheic syndrome and CD4+ T lymphocyte counts < 200 cells/mm 3 , demonstrating the opportunistic characteristic of these infections. A significant association was observed between the lack of adherence to antiretroviral therapy and the presence of Cryptosporidium spp. and/or C. belli. Parasitism with Cryptosporidium spp. was more frequent in February and April, the months following the period of high rainfall. The same was not observed for C. belli. Genetic characterization of two isolates led to the identification of Cryptosporidium parvum, one of the main species associated with the zoonotic transmission of cryptosporidiosis. |
format |
Article in Journal/Newspaper |
author |
Dnieber Chagas Assis Deisy Vivian Resende Marlene Cabrine-Santos Dalmo Correia Márcia Benedita Oliveira-Silva |
author_facet |
Dnieber Chagas Assis Deisy Vivian Resende Marlene Cabrine-Santos Dalmo Correia Márcia Benedita Oliveira-Silva |
author_sort |
Dnieber Chagas Assis |
title |
Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
title_short |
Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
title_full |
Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
title_fullStr |
Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
title_full_unstemmed |
Prevalence and genetic characterization of Cryptosporidium spp. and Cystoisospora belli in HIV-infected patients |
title_sort |
prevalence and genetic characterization of cryptosporidium spp. and cystoisospora belli in hiv-infected patients |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2013 |
url |
https://doi.org/10.1590/S0036-46652013000300002 https://doaj.org/article/72ce178469684bd5943985296c2a465c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 55, Iss 3, Pp 149-154 (2013) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652013000300149&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652013000300002 https://doaj.org/article/72ce178469684bd5943985296c2a465c |
op_doi |
https://doi.org/10.1590/S0036-46652013000300002 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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55 |
container_issue |
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149 |
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