Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment
Mario A Rodríguez-Pérez1, Juan Antonio Pérez-Vega2, José Francisco Cen-Aguilar3, Rossanna Rodríguez-Canul21Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Ciudad Reynosa, Tamaulipas, 2Centro de Investigación y de Estudios Avanzados del IPN Unidad Mérida, Mérida Yucatán, 3Oficina de...
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ftdoajarticles:oai:doaj.org/article:7236932e38d941f8845f0d854f561ce9 2023-05-15T15:14:06+02:00 Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment Rodríguez-Pérez MA Pérez-Vega JA Cen-Aguilar JF Rodríguez-Canul R 2011-12-01T00:00:00Z https://doaj.org/article/7236932e38d941f8845f0d854f561ce9 EN eng Dove Medical Press http://www.dovepress.com/lessons-from-a-study-in-a-rural-community-from-southern-mexico-risk-fa-a8852 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/7236932e38d941f8845f0d854f561ce9 Research and Reports in Tropical Medicine, Vol 2011, Iss default, Pp 147-153 (2011) Arctic medicine. Tropical medicine RC955-962 article 2011 ftdoajarticles 2022-12-31T04:49:15Z Mario A Rodríguez-Pérez1, Juan Antonio Pérez-Vega2, José Francisco Cen-Aguilar3, Rossanna Rodríguez-Canul21Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Ciudad Reynosa, Tamaulipas, 2Centro de Investigación y de Estudios Avanzados del IPN Unidad Mérida, Mérida Yucatán, 3Oficina de Investigación y validación, Centro de Bachillerato Tecnológico y Agropecuario (CBTA) 13, Xmatkuil, Mérida, Yucatán, MexicoPurpose: To determine the prevalence of gastrointestinal parasites and evaluate the effect of a single dose of treatment with albendazole in a sentinel group from a rural community in southern Mexico.Methods: Stool samples were collected from 1456 individuals aged ≥1 year during consecutive days, and examined for helminth infection using the modified Stoll dilution method. Additionally, 104 individuals were treated with a single dose of albendazole and evaluated over 21 weeks to assess reinfection. Questionnaires were administered to obtain individual and household-level data pertaining to behavior, demography, and socioeconomic status. Risk factors for reinfection after albendazole administration were determined using multiple logistic regression analyses.Results: The prevalence of Ascaris lumbricoides was 73.9% (95% confidence interval [CI] = 71.56%–76.14%). Albendazole was 100% effective, but eggs began to be detected by 9–12 weeks posttreatment, increasing to 100% after 21 weeks. Logistic regression analysis revealed that all individuals from this study had a probability of reinfection of 1.65× each week after treatment. The prevalence of Trichuris trichiura was 57.2% (95% CI = 54.62%–59.77%) and chemotherapy was 34.7% effective. The prevalence for other minor gastrointestinal parasites ranged from 0.2% to 29.7%.Conclusion: This was a comprehensive study on gastrointestinal parasites in a rural community from southern Mexico and, to the best of the authors’ knowledge, is the first time that the effect of albendazole has been evaluated for a period of over 21 weeks following its administration. ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Rodríguez-Pérez MA Pérez-Vega JA Cen-Aguilar JF Rodríguez-Canul R Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Mario A Rodríguez-Pérez1, Juan Antonio Pérez-Vega2, José Francisco Cen-Aguilar3, Rossanna Rodríguez-Canul21Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Ciudad Reynosa, Tamaulipas, 2Centro de Investigación y de Estudios Avanzados del IPN Unidad Mérida, Mérida Yucatán, 3Oficina de Investigación y validación, Centro de Bachillerato Tecnológico y Agropecuario (CBTA) 13, Xmatkuil, Mérida, Yucatán, MexicoPurpose: To determine the prevalence of gastrointestinal parasites and evaluate the effect of a single dose of treatment with albendazole in a sentinel group from a rural community in southern Mexico.Methods: Stool samples were collected from 1456 individuals aged ≥1 year during consecutive days, and examined for helminth infection using the modified Stoll dilution method. Additionally, 104 individuals were treated with a single dose of albendazole and evaluated over 21 weeks to assess reinfection. Questionnaires were administered to obtain individual and household-level data pertaining to behavior, demography, and socioeconomic status. Risk factors for reinfection after albendazole administration were determined using multiple logistic regression analyses.Results: The prevalence of Ascaris lumbricoides was 73.9% (95% confidence interval [CI] = 71.56%–76.14%). Albendazole was 100% effective, but eggs began to be detected by 9–12 weeks posttreatment, increasing to 100% after 21 weeks. Logistic regression analysis revealed that all individuals from this study had a probability of reinfection of 1.65× each week after treatment. The prevalence of Trichuris trichiura was 57.2% (95% CI = 54.62%–59.77%) and chemotherapy was 34.7% effective. The prevalence for other minor gastrointestinal parasites ranged from 0.2% to 29.7%.Conclusion: This was a comprehensive study on gastrointestinal parasites in a rural community from southern Mexico and, to the best of the authors’ knowledge, is the first time that the effect of albendazole has been evaluated for a period of over 21 weeks following its administration. ... |
format |
Article in Journal/Newspaper |
author |
Rodríguez-Pérez MA Pérez-Vega JA Cen-Aguilar JF Rodríguez-Canul R |
author_facet |
Rodríguez-Pérez MA Pérez-Vega JA Cen-Aguilar JF Rodríguez-Canul R |
author_sort |
Rodríguez-Pérez MA |
title |
Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
title_short |
Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
title_full |
Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
title_fullStr |
Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
title_full_unstemmed |
Lessons from a study in a rural community from southern Mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
title_sort |
lessons from a study in a rural community from southern mexico: risk factors associated to transmission and reinfection of gastrointestinal parasites after albendazole treatment |
publisher |
Dove Medical Press |
publishDate |
2011 |
url |
https://doaj.org/article/7236932e38d941f8845f0d854f561ce9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Research and Reports in Tropical Medicine, Vol 2011, Iss default, Pp 147-153 (2011) |
op_relation |
http://www.dovepress.com/lessons-from-a-study-in-a-rural-community-from-southern-mexico-risk-fa-a8852 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/7236932e38d941f8845f0d854f561ce9 |
_version_ |
1766344606550589440 |