Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya
Abstract Background Interventions to reverse trends in malaria-related morbidity and mortality in Kenya focus on preventive strategies and drug efficacy. However, the pattern of use of anti-malarials in malaria-endemic populations, such as in western Kenya, is still poorly understood. It is critical...
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ftdoajarticles:oai:doaj.org/article:72042dc9eb5046b0a44a689b8d67ed07 2023-05-15T15:16:43+02:00 Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya Abong'o Benard Oyugi Henry Jura Walter GZO Watsierah Carren A Ouma Collins 2010-10-01T00:00:00Z https://doi.org/10.1186/1475-2875-9-295 https://doaj.org/article/72042dc9eb5046b0a44a689b8d67ed07 EN eng BMC http://www.malariajournal.com/content/9/1/295 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-295 1475-2875 https://doaj.org/article/72042dc9eb5046b0a44a689b8d67ed07 Malaria Journal, Vol 9, Iss 1, p 295 (2010) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2010 ftdoajarticles https://doi.org/10.1186/1475-2875-9-295 2022-12-31T08:45:32Z Abstract Background Interventions to reverse trends in malaria-related morbidity and mortality in Kenya focus on preventive strategies and drug efficacy. However, the pattern of use of anti-malarials in malaria-endemic populations, such as in western Kenya, is still poorly understood. It is critical to understand the patterns of anti-malarial drug use to ascertain that the currently applied new combination therapy to malaria treatment, will achieve sustained cure rates and protection against parasite resistance. Therefore, this cross-sectional study was designed to determine the patterns of use of anti-malarial drugs in households (n = 397) in peri-urban location of Manyatta-B sub-location in Kisumu in western Kenya. Methods Household factors, associated with the pattern of anti-malarials use, were evaluated. Using clusters, questionnaire was administered to a particular household member who had the most recent malaria episode (within <2 weeks) and used an anti-malarial for cure. Mothers/caretakers provided information for children aged <13 years. Results Stratification of the type of anti-malarial drugs taken revealed that 37.0% used sulphadoxine/pyrimethamine (SP), 32.0% artemisinin-based combined therapy (ACT), 11.1% anti-pyretics, 7.3% chloroquine (CQ), 7.1% quinine, 2.5% amodiaquine (AQ), while 3.0% used others which were perceived as anti-malarials (cough syrups and antibiotics). In a regression model, it was demonstrated that age ( P = 0.050), household size ( P = 0.047), household head ( P = 0.049), household source of income ( P = 0.015), monthly income ( P = 0.020), duration of use ( P = 0.029), dosage of drugs taken ( P = 0.036), and source of drugs ( P = 0.005) significantly influenced anti-malarial drug use. Overall, 38.8% of respondents used drugs as recommended by the Ministry of Health. Conclusion This study demonstrates that consumers require access to correct and comprehensible information associated with use of drugs, including self-prescription. There is potential need by the Kenyan ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 9 1 295 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Abong'o Benard Oyugi Henry Jura Walter GZO Watsierah Carren A Ouma Collins Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Interventions to reverse trends in malaria-related morbidity and mortality in Kenya focus on preventive strategies and drug efficacy. However, the pattern of use of anti-malarials in malaria-endemic populations, such as in western Kenya, is still poorly understood. It is critical to understand the patterns of anti-malarial drug use to ascertain that the currently applied new combination therapy to malaria treatment, will achieve sustained cure rates and protection against parasite resistance. Therefore, this cross-sectional study was designed to determine the patterns of use of anti-malarial drugs in households (n = 397) in peri-urban location of Manyatta-B sub-location in Kisumu in western Kenya. Methods Household factors, associated with the pattern of anti-malarials use, were evaluated. Using clusters, questionnaire was administered to a particular household member who had the most recent malaria episode (within <2 weeks) and used an anti-malarial for cure. Mothers/caretakers provided information for children aged <13 years. Results Stratification of the type of anti-malarial drugs taken revealed that 37.0% used sulphadoxine/pyrimethamine (SP), 32.0% artemisinin-based combined therapy (ACT), 11.1% anti-pyretics, 7.3% chloroquine (CQ), 7.1% quinine, 2.5% amodiaquine (AQ), while 3.0% used others which were perceived as anti-malarials (cough syrups and antibiotics). In a regression model, it was demonstrated that age ( P = 0.050), household size ( P = 0.047), household head ( P = 0.049), household source of income ( P = 0.015), monthly income ( P = 0.020), duration of use ( P = 0.029), dosage of drugs taken ( P = 0.036), and source of drugs ( P = 0.005) significantly influenced anti-malarial drug use. Overall, 38.8% of respondents used drugs as recommended by the Ministry of Health. Conclusion This study demonstrates that consumers require access to correct and comprehensible information associated with use of drugs, including self-prescription. There is potential need by the Kenyan ... |
format |
Article in Journal/Newspaper |
author |
Abong'o Benard Oyugi Henry Jura Walter GZO Watsierah Carren A Ouma Collins |
author_facet |
Abong'o Benard Oyugi Henry Jura Walter GZO Watsierah Carren A Ouma Collins |
author_sort |
Abong'o Benard |
title |
Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
title_short |
Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
title_full |
Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
title_fullStr |
Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
title_full_unstemmed |
Factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
title_sort |
factors determining anti-malarial drug use in a peri-urban population from malaria holoendemic region of western kenya |
publisher |
BMC |
publishDate |
2010 |
url |
https://doi.org/10.1186/1475-2875-9-295 https://doaj.org/article/72042dc9eb5046b0a44a689b8d67ed07 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 9, Iss 1, p 295 (2010) |
op_relation |
http://www.malariajournal.com/content/9/1/295 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-9-295 1475-2875 https://doaj.org/article/72042dc9eb5046b0a44a689b8d67ed07 |
op_doi |
https://doi.org/10.1186/1475-2875-9-295 |
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Malaria Journal |
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9 |
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1 |
container_start_page |
295 |
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1766347017472180224 |