Treatment of Schistosoma mansoni with miltefosine in vitro enhances serological recognition of defined worm surface antigens.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Marwa H El-Faham, Maha M Eissa, Joseph E Igetei, Eglal I Amer, Susan Liddell, Mervat Z El-Azzouni, Michael J Doenhoff
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2017
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Lent
• Online Access: https://doi.org/10.1371/journal.pntd.0005853; https://doaj.org/article/71baeeda75804683bf1f2ae2cbb330c6

Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of the parasite. The current study examined the effect of treating Schistosoma mansoni ad...