Subcutaneous phaeohyphomycosis due to Cladophialophora bantiana: a first case report in an immunocompetent patient in Latin America and a brief literature review

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Gustavo Ávila Maquiné, Marcos Henrique Gurgel Rodrigues, Antônio Pedro Mendes Schettini, Patricia Motta de Morais, Maria Zeli Moreira Frota
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Cladophialophora bantiana; Subcutaneous phaeohyphomycosis; Antifungal susceptibility; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0480-2018; https://doaj.org/article/7149edd958274156a9b29dff2e0ade5c

Abstract We report a rare case of subcutaneous phaeohyphomycosis caused by Cladophialophora bantiana in an immunocompetent patient in Amazonas, Brazil. This dematiaceous fungus has been mainly associated with life-threatening infections affecting the central nervous systems of immunosuppressed patients. We present the clinical, laboratory, and therapeutic aspects, and in vitro susceptibility test results for different antifungal drugs. A brief review of the cases reported in the literature over the past 20 years has also been discussed. According to the literature review, the present case is the first report of subcutaneous phaeohyphomycosis due to C. bantiana in an immunocompetent patient in Latin America.