Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon.
Background In the clinical course of diseases such as arboviruses, skin rashes may appear, as is often seen in other infectious diseases. The aim of this study was to estimate the prevalence of arboviruses and other infectious causes of skin rash in a tertiary health unit in Manaus, Amazonas state,...
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ftdoajarticles:oai:doaj.org/article:70d780731b7447678427fda92bb0d78a 2023-05-15T15:17:35+02:00 Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. Luiz Henrique Gonçalves Maciel Cosmo Vieira da Rocha Neto Yasmin Ferreira Martins Francielen de Azevedo Furtado Pâmela Cunha Teixeira Maianne Yasmin Oliveira Dias Yanka Karolinna Batista Rodrigues Isa Cristina Ribeiro Piauilino Sérgio Damasceno Pinto Aline Cristiane Côrte Alencar João Bosco de Lima Gimaque Maria Paula Gomes Mourão Marcus Vinicius Guimarães Lacerda Márcia da Costa Castilho Camila Bôtto-Menezes 2022-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0010727 https://doaj.org/article/70d780731b7447678427fda92bb0d78a EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0010727 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010727 https://doaj.org/article/70d780731b7447678427fda92bb0d78a PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010727 (2022) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles https://doi.org/10.1371/journal.pntd.0010727 2022-12-30T21:43:40Z Background In the clinical course of diseases such as arboviruses, skin rashes may appear, as is often seen in other infectious diseases. The aim of this study was to estimate the prevalence of arboviruses and other infectious causes of skin rash in a tertiary health unit in Manaus, Amazonas state, Western Brazilian Amazon. Methodology/principal findings This was a cross-sectional study of patients presenting with rash who sought care at Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD) from February 2018 to May 2019. Individuals of either gender, aged over 18 years, were invited to participate voluntarily. Infection by Zika virus (ZIKV), dengue virus (DENV), chikungunya virus (CHIKV), Mayaro virus (MAYV), Oropouche virus (OROV) and measles was evaluated using RT-qPCR (real-time polymerase chain reaction). Immunodiagnostic tests for EBV, CMV, HIV, syphilis, rubella and measles were also performed. A total of 340 participants were included, most were female (228, 67.1%) with an average age of 36.5 years (SD ± 12.2 years). The highest prevalence was of ZIKV monoinfections (65.3%, 222/340), followed by DENV (0.9%, 3/340) and CHIKV infection (0.3%, 1/340). No cases of MAYV, OROV or rubella were found. Other causes of skin rash were detected: measles (2.9%, 10/340), parvovirus B19 (0.9% 3/340), HIV (0.3%, 1/340) and syphilis 0.6% (2/340). The co-infections identified were ZIKV+HIV (0.3%, 1/340), ZIKV+measles (0.3%, 1/340), ZIKV+parvovirus B19 (0.3%, 1/340), ZIKV+EBV (0.3%, 1/340), EBV+parvovirus B19 (0.3%, 1/340), CMV+parvovirus B19 (0.6%, 2/340), CMV+syphilis (0.3%, 1/340), ZIKV+EBV+parvovirus B19 (0.3%, 1/340) and CMV+EBV+parvovirus B19 (0.9%, 3/340). Approximately one quarter of patients had no defined cause for their skin rash (25.3%, 86/340). Conclusions Despite the benign clinical evolution of most of the diseases diagnosed in this series of cases, syndromic surveillance of diseases such as syphilis and HIV are of utmost importance. Periodic serosurveillance might also aid in evaluating the ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 16 10 e0010727 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Luiz Henrique Gonçalves Maciel Cosmo Vieira da Rocha Neto Yasmin Ferreira Martins Francielen de Azevedo Furtado Pâmela Cunha Teixeira Maianne Yasmin Oliveira Dias Yanka Karolinna Batista Rodrigues Isa Cristina Ribeiro Piauilino Sérgio Damasceno Pinto Aline Cristiane Côrte Alencar João Bosco de Lima Gimaque Maria Paula Gomes Mourão Marcus Vinicius Guimarães Lacerda Márcia da Costa Castilho Camila Bôtto-Menezes Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background In the clinical course of diseases such as arboviruses, skin rashes may appear, as is often seen in other infectious diseases. The aim of this study was to estimate the prevalence of arboviruses and other infectious causes of skin rash in a tertiary health unit in Manaus, Amazonas state, Western Brazilian Amazon. Methodology/principal findings This was a cross-sectional study of patients presenting with rash who sought care at Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (FMT-HVD) from February 2018 to May 2019. Individuals of either gender, aged over 18 years, were invited to participate voluntarily. Infection by Zika virus (ZIKV), dengue virus (DENV), chikungunya virus (CHIKV), Mayaro virus (MAYV), Oropouche virus (OROV) and measles was evaluated using RT-qPCR (real-time polymerase chain reaction). Immunodiagnostic tests for EBV, CMV, HIV, syphilis, rubella and measles were also performed. A total of 340 participants were included, most were female (228, 67.1%) with an average age of 36.5 years (SD ± 12.2 years). The highest prevalence was of ZIKV monoinfections (65.3%, 222/340), followed by DENV (0.9%, 3/340) and CHIKV infection (0.3%, 1/340). No cases of MAYV, OROV or rubella were found. Other causes of skin rash were detected: measles (2.9%, 10/340), parvovirus B19 (0.9% 3/340), HIV (0.3%, 1/340) and syphilis 0.6% (2/340). The co-infections identified were ZIKV+HIV (0.3%, 1/340), ZIKV+measles (0.3%, 1/340), ZIKV+parvovirus B19 (0.3%, 1/340), ZIKV+EBV (0.3%, 1/340), EBV+parvovirus B19 (0.3%, 1/340), CMV+parvovirus B19 (0.6%, 2/340), CMV+syphilis (0.3%, 1/340), ZIKV+EBV+parvovirus B19 (0.3%, 1/340) and CMV+EBV+parvovirus B19 (0.9%, 3/340). Approximately one quarter of patients had no defined cause for their skin rash (25.3%, 86/340). Conclusions Despite the benign clinical evolution of most of the diseases diagnosed in this series of cases, syndromic surveillance of diseases such as syphilis and HIV are of utmost importance. Periodic serosurveillance might also aid in evaluating the ... |
format |
Article in Journal/Newspaper |
author |
Luiz Henrique Gonçalves Maciel Cosmo Vieira da Rocha Neto Yasmin Ferreira Martins Francielen de Azevedo Furtado Pâmela Cunha Teixeira Maianne Yasmin Oliveira Dias Yanka Karolinna Batista Rodrigues Isa Cristina Ribeiro Piauilino Sérgio Damasceno Pinto Aline Cristiane Côrte Alencar João Bosco de Lima Gimaque Maria Paula Gomes Mourão Marcus Vinicius Guimarães Lacerda Márcia da Costa Castilho Camila Bôtto-Menezes |
author_facet |
Luiz Henrique Gonçalves Maciel Cosmo Vieira da Rocha Neto Yasmin Ferreira Martins Francielen de Azevedo Furtado Pâmela Cunha Teixeira Maianne Yasmin Oliveira Dias Yanka Karolinna Batista Rodrigues Isa Cristina Ribeiro Piauilino Sérgio Damasceno Pinto Aline Cristiane Côrte Alencar João Bosco de Lima Gimaque Maria Paula Gomes Mourão Marcus Vinicius Guimarães Lacerda Márcia da Costa Castilho Camila Bôtto-Menezes |
author_sort |
Luiz Henrique Gonçalves Maciel |
title |
Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
title_short |
Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
title_full |
Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
title_fullStr |
Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
title_full_unstemmed |
Prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the Brazilian Amazon. |
title_sort |
prevalence of arboviruses and other infectious causes of skin rash in patients treated at a tertiary health unit in the brazilian amazon. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2022 |
url |
https://doi.org/10.1371/journal.pntd.0010727 https://doaj.org/article/70d780731b7447678427fda92bb0d78a |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010727 (2022) |
op_relation |
https://doi.org/10.1371/journal.pntd.0010727 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010727 https://doaj.org/article/70d780731b7447678427fda92bb0d78a |
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https://doi.org/10.1371/journal.pntd.0010727 |
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PLOS Neglected Tropical Diseases |
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