Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia.
Background Colombia has one of the highest burdens of arboviruses in South America. The country was in a state of hyperendemicity between 2014 and 2016, with co-circulation of several Aedes-borne viruses, including a syndemic of dengue, chikungunya, and Zika in 2015. Methodology/principal findings W...
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ftdoajarticles:oai:doaj.org/article:70c46a63a1614260a18bc724db6e14ab 2023-05-15T15:12:45+02:00 Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. Laís Picinini Freitas Mabel Carabali Mengru Yuan Gloria I Jaramillo-Ramirez Cesar Garcia Balaguera Berta N Restrepo Kate Zinszer 2022-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0010334 https://doaj.org/article/70c46a63a1614260a18bc724db6e14ab EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0010334 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010334 https://doaj.org/article/70c46a63a1614260a18bc724db6e14ab PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010334 (2022) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles https://doi.org/10.1371/journal.pntd.0010334 2022-12-31T00:05:24Z Background Colombia has one of the highest burdens of arboviruses in South America. The country was in a state of hyperendemicity between 2014 and 2016, with co-circulation of several Aedes-borne viruses, including a syndemic of dengue, chikungunya, and Zika in 2015. Methodology/principal findings We analyzed the cases of dengue, chikungunya, and Zika notified in Colombia from January 2014 to December 2018 by municipality and week. The trajectory and velocity of spread was studied using trend surface analysis, and spatio-temporal high-risk clusters for each disease in separate and for the three diseases simultaneously (multivariate) were identified using Kulldorff's scan statistics. During the study period, there were 366,628, 77,345 and 74,793 cases of dengue, chikungunya, and Zika, respectively, in Colombia. The spread patterns for chikungunya and Zika were similar, although Zika's spread was accelerated. Both chikungunya and Zika mainly spread from the regions on the Atlantic coast and the south-west to the rest of the country. We identified 21, 16, and 13 spatio-temporal clusters of dengue, chikungunya and Zika, respectively, and, from the multivariate analysis, 20 spatio-temporal clusters, among which 7 were simultaneous for the three diseases. For all disease-specific analyses and the multivariate analysis, the most-likely cluster was identified in the south-western region of Colombia, including the Valle del Cauca department. Conclusions/significance The results further our understanding of emerging Aedes-borne diseases in Colombia by providing useful evidence on their potential site of entry and spread trajectory within the country, and identifying spatio-temporal disease-specific and multivariate high-risk clusters of dengue, chikungunya, and Zika, information that can be used to target interventions. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 16 8 e0010334 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Laís Picinini Freitas Mabel Carabali Mengru Yuan Gloria I Jaramillo-Ramirez Cesar Garcia Balaguera Berta N Restrepo Kate Zinszer Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Colombia has one of the highest burdens of arboviruses in South America. The country was in a state of hyperendemicity between 2014 and 2016, with co-circulation of several Aedes-borne viruses, including a syndemic of dengue, chikungunya, and Zika in 2015. Methodology/principal findings We analyzed the cases of dengue, chikungunya, and Zika notified in Colombia from January 2014 to December 2018 by municipality and week. The trajectory and velocity of spread was studied using trend surface analysis, and spatio-temporal high-risk clusters for each disease in separate and for the three diseases simultaneously (multivariate) were identified using Kulldorff's scan statistics. During the study period, there were 366,628, 77,345 and 74,793 cases of dengue, chikungunya, and Zika, respectively, in Colombia. The spread patterns for chikungunya and Zika were similar, although Zika's spread was accelerated. Both chikungunya and Zika mainly spread from the regions on the Atlantic coast and the south-west to the rest of the country. We identified 21, 16, and 13 spatio-temporal clusters of dengue, chikungunya and Zika, respectively, and, from the multivariate analysis, 20 spatio-temporal clusters, among which 7 were simultaneous for the three diseases. For all disease-specific analyses and the multivariate analysis, the most-likely cluster was identified in the south-western region of Colombia, including the Valle del Cauca department. Conclusions/significance The results further our understanding of emerging Aedes-borne diseases in Colombia by providing useful evidence on their potential site of entry and spread trajectory within the country, and identifying spatio-temporal disease-specific and multivariate high-risk clusters of dengue, chikungunya, and Zika, information that can be used to target interventions. |
format |
Article in Journal/Newspaper |
author |
Laís Picinini Freitas Mabel Carabali Mengru Yuan Gloria I Jaramillo-Ramirez Cesar Garcia Balaguera Berta N Restrepo Kate Zinszer |
author_facet |
Laís Picinini Freitas Mabel Carabali Mengru Yuan Gloria I Jaramillo-Ramirez Cesar Garcia Balaguera Berta N Restrepo Kate Zinszer |
author_sort |
Laís Picinini Freitas |
title |
Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
title_short |
Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
title_full |
Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
title_fullStr |
Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
title_full_unstemmed |
Spatio-temporal clusters and patterns of spread of dengue, chikungunya, and Zika in Colombia. |
title_sort |
spatio-temporal clusters and patterns of spread of dengue, chikungunya, and zika in colombia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2022 |
url |
https://doi.org/10.1371/journal.pntd.0010334 https://doaj.org/article/70c46a63a1614260a18bc724db6e14ab |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 16, Iss 8, p e0010334 (2022) |
op_relation |
https://doi.org/10.1371/journal.pntd.0010334 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010334 https://doaj.org/article/70c46a63a1614260a18bc724db6e14ab |
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https://doi.org/10.1371/journal.pntd.0010334 |
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PLOS Neglected Tropical Diseases |
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e0010334 |
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