Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India
Objective: To report cases of neurocysticercosis (NCC) from three neighboring districts of Andhra Pradesh state in India where NCC burden was never explored before. Methods: A total of 160 patients presenting with recent onset seizures were recruited from neurology, general medicine, and pediatric o...
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Wolters Kluwer Medknow Publications
2016
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ftdoajarticles:oai:doaj.org/article:702477c4df78428eab61a8fca536b795 2023-05-15T15:08:40+02:00 Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India Bala Chandra Sekhar Pappala Jyothi Padmaja Indugula Sateesh Kumar Talabhatula Ramalakshmi Suryakarani Kolli Arpit Kumar Shrivastava Priyadarshi Soumyaranjan Sahu 2016-11-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2016.09.001 https://doaj.org/article/702477c4df78428eab61a8fca536b795 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169116300119 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.09.001 https://doaj.org/article/702477c4df78428eab61a8fca536b795 Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 11, Pp 903-908 (2016) Neurocysticercosis Cysticercosis Seizures Andhra Pradesh Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2016 ftdoajarticles https://doi.org/10.1016/j.apjtb.2016.09.001 2022-12-31T15:01:10Z Objective: To report cases of neurocysticercosis (NCC) from three neighboring districts of Andhra Pradesh state in India where NCC burden was never explored before. Methods: A total of 160 patients presenting with recent onset seizures were recruited from neurology, general medicine, and pediatric outpatient clinics of a local major tertiary care teaching hospital serving above districts during the period 2011–2014. Brain imaging was performed in all the above cases. A commercial immunoglobulin G-ELISA kit (sensitivity = 85%; specificity = 94%) was employed for the serological diagnosis of NCC. Results: The recruited patients presented with generalized, simple partial, and complex partial seizures (55%, 31.25% and 13.75% respectively). NCC was diagnosed in 44 of 160 (27.5%) seizure cases based on imaging characteristics, and a positive serum antibody ELISA. No association was detected between seropositivity with the number and location of the lesion(s) in the brain. Conclusions: The possible potentiality of NCC could be identified as an underlying cause of the recent onset of seizures in this region as explored in the present study. It is recommended that NCC should be suspected as one of the major differential in every recent onset seizure with or without a radio imaging supportive diagnosis, especially in areas endemic for taeniasis/cysticercosis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 6 11 903 908 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Neurocysticercosis Cysticercosis Seizures Andhra Pradesh Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Neurocysticercosis Cysticercosis Seizures Andhra Pradesh Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Bala Chandra Sekhar Pappala Jyothi Padmaja Indugula Sateesh Kumar Talabhatula Ramalakshmi Suryakarani Kolli Arpit Kumar Shrivastava Priyadarshi Soumyaranjan Sahu Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
topic_facet |
Neurocysticercosis Cysticercosis Seizures Andhra Pradesh Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To report cases of neurocysticercosis (NCC) from three neighboring districts of Andhra Pradesh state in India where NCC burden was never explored before. Methods: A total of 160 patients presenting with recent onset seizures were recruited from neurology, general medicine, and pediatric outpatient clinics of a local major tertiary care teaching hospital serving above districts during the period 2011–2014. Brain imaging was performed in all the above cases. A commercial immunoglobulin G-ELISA kit (sensitivity = 85%; specificity = 94%) was employed for the serological diagnosis of NCC. Results: The recruited patients presented with generalized, simple partial, and complex partial seizures (55%, 31.25% and 13.75% respectively). NCC was diagnosed in 44 of 160 (27.5%) seizure cases based on imaging characteristics, and a positive serum antibody ELISA. No association was detected between seropositivity with the number and location of the lesion(s) in the brain. Conclusions: The possible potentiality of NCC could be identified as an underlying cause of the recent onset of seizures in this region as explored in the present study. It is recommended that NCC should be suspected as one of the major differential in every recent onset seizure with or without a radio imaging supportive diagnosis, especially in areas endemic for taeniasis/cysticercosis. |
format |
Article in Journal/Newspaper |
author |
Bala Chandra Sekhar Pappala Jyothi Padmaja Indugula Sateesh Kumar Talabhatula Ramalakshmi Suryakarani Kolli Arpit Kumar Shrivastava Priyadarshi Soumyaranjan Sahu |
author_facet |
Bala Chandra Sekhar Pappala Jyothi Padmaja Indugula Sateesh Kumar Talabhatula Ramalakshmi Suryakarani Kolli Arpit Kumar Shrivastava Priyadarshi Soumyaranjan Sahu |
author_sort |
Bala Chandra Sekhar Pappala |
title |
Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
title_short |
Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
title_full |
Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
title_fullStr |
Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
title_full_unstemmed |
Diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of Andhra Pradesh, India |
title_sort |
diagnosis of neurocysticercosis among patients with seizures in northern coastal districts of andhra pradesh, india |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2016 |
url |
https://doi.org/10.1016/j.apjtb.2016.09.001 https://doaj.org/article/702477c4df78428eab61a8fca536b795 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 6, Iss 11, Pp 903-908 (2016) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169116300119 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2016.09.001 https://doaj.org/article/702477c4df78428eab61a8fca536b795 |
op_doi |
https://doi.org/10.1016/j.apjtb.2016.09.001 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
6 |
container_issue |
11 |
container_start_page |
903 |
op_container_end_page |
908 |
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1766339981743226880 |