Safety and tolerability of moxidectin and ivermectin combination treatments for lymphatic filariasis in Côte d'Ivoire: A randomized controlled superiority study.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Catherine M Bjerum, Benjamin G Koudou, Allassane F Ouattara, Daphne Lew, Charles W Goss, Pascal T Gabo, Christopher L King, Peter U Fischer, Gary J Weil, Philip J Budge
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2023
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Ida
• Online Access: https://doi.org/10.1371/journal.pntd.0011633; https://doaj.org/article/700673892a3b44b5a4de81b30bb18bb0

Background Moxidectin is a macrocyclic lactone registered for the treatment of human onchocerciasis. The drug has a good safety profile, large volume of distribution and a long elimination half-life. This paper reports tolerability data from the first use of moxidectin in persons with Wuchereria ban...