Imported amoebic liver abscess in France.
BACKGROUND: Worldwide, amoebic liver abscess (ALA) can be found in individuals in non-endemic areas, especially in foreign-born travelers. METHODS: We performed a retrospective analysis of ALA in patients admitted to French hospitals between 2002 and 2006. We compared imported ALA cases in European...
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ftdoajarticles:oai:doaj.org/article:6f87db417df14e03a1e6c441cfb5e212 2023-05-15T15:11:48+02:00 Imported amoebic liver abscess in France. Hugues Cordel Virginie Prendki Yoann Madec Sandrine Houze Luc Paris Patrice Bourée Eric Caumes Sophie Matheron Olivier Bouchaud ALA Study Group 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002333 https://doaj.org/article/6f87db417df14e03a1e6c441cfb5e212 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3738465?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002333 https://doaj.org/article/6f87db417df14e03a1e6c441cfb5e212 PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2333 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002333 2022-12-31T05:33:58Z BACKGROUND: Worldwide, amoebic liver abscess (ALA) can be found in individuals in non-endemic areas, especially in foreign-born travelers. METHODS: We performed a retrospective analysis of ALA in patients admitted to French hospitals between 2002 and 2006. We compared imported ALA cases in European and foreign-born patients and assessed the factors associated with abscess size using a logistic regression model. RESULTS: We investigated 90 ALA cases. Patient median age was 41. The male:female ratio was 3.5:1. We were able to determine the origin for 75 patients: 38 were European-born and 37 foreign-born. With respect to clinical characteristics, no significant difference was observed between European and foreign-born patients except a longer lag time between the return to France after traveling abroad and the onset of symptoms for foreign-born. Factors associated with an abscess size of more than 69 mm were being male (OR = 11.25, p<0.01), aged more than 41 years old (OR = 3.63, p = 0.02) and being an immigrant (OR = 11.56, p = 0.03). Percutaneous aspiration was not based on initial abscess size but was carried out significantly more often on patients who were admitted to surgical units (OR = 10, p<0.01). The median time to abscess disappearance for 24 ALA was 7.5 months. CONCLUSIONS/SIGNIFICANCE: In this study on imported ALA was one of the largest worldwide in terms of the number of cases included males, older patients and foreign-born patients presented with larger abscesses, suggesting that hormonal and immunological factors may be involved in ALA physiopathology. The long lag time before developing ALA after returning to a non-endemic area must be highlighted to clinicians so that they will consider Entamoeba histolytica as a possible pathogen of liver abscesses more often. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 7 8 e2333 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Hugues Cordel Virginie Prendki Yoann Madec Sandrine Houze Luc Paris Patrice Bourée Eric Caumes Sophie Matheron Olivier Bouchaud ALA Study Group Imported amoebic liver abscess in France. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND: Worldwide, amoebic liver abscess (ALA) can be found in individuals in non-endemic areas, especially in foreign-born travelers. METHODS: We performed a retrospective analysis of ALA in patients admitted to French hospitals between 2002 and 2006. We compared imported ALA cases in European and foreign-born patients and assessed the factors associated with abscess size using a logistic regression model. RESULTS: We investigated 90 ALA cases. Patient median age was 41. The male:female ratio was 3.5:1. We were able to determine the origin for 75 patients: 38 were European-born and 37 foreign-born. With respect to clinical characteristics, no significant difference was observed between European and foreign-born patients except a longer lag time between the return to France after traveling abroad and the onset of symptoms for foreign-born. Factors associated with an abscess size of more than 69 mm were being male (OR = 11.25, p<0.01), aged more than 41 years old (OR = 3.63, p = 0.02) and being an immigrant (OR = 11.56, p = 0.03). Percutaneous aspiration was not based on initial abscess size but was carried out significantly more often on patients who were admitted to surgical units (OR = 10, p<0.01). The median time to abscess disappearance for 24 ALA was 7.5 months. CONCLUSIONS/SIGNIFICANCE: In this study on imported ALA was one of the largest worldwide in terms of the number of cases included males, older patients and foreign-born patients presented with larger abscesses, suggesting that hormonal and immunological factors may be involved in ALA physiopathology. The long lag time before developing ALA after returning to a non-endemic area must be highlighted to clinicians so that they will consider Entamoeba histolytica as a possible pathogen of liver abscesses more often. |
format |
Article in Journal/Newspaper |
author |
Hugues Cordel Virginie Prendki Yoann Madec Sandrine Houze Luc Paris Patrice Bourée Eric Caumes Sophie Matheron Olivier Bouchaud ALA Study Group |
author_facet |
Hugues Cordel Virginie Prendki Yoann Madec Sandrine Houze Luc Paris Patrice Bourée Eric Caumes Sophie Matheron Olivier Bouchaud ALA Study Group |
author_sort |
Hugues Cordel |
title |
Imported amoebic liver abscess in France. |
title_short |
Imported amoebic liver abscess in France. |
title_full |
Imported amoebic liver abscess in France. |
title_fullStr |
Imported amoebic liver abscess in France. |
title_full_unstemmed |
Imported amoebic liver abscess in France. |
title_sort |
imported amoebic liver abscess in france. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doi.org/10.1371/journal.pntd.0002333 https://doaj.org/article/6f87db417df14e03a1e6c441cfb5e212 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2333 (2013) |
op_relation |
http://europepmc.org/articles/PMC3738465?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002333 https://doaj.org/article/6f87db417df14e03a1e6c441cfb5e212 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002333 |
container_title |
PLoS Neglected Tropical Diseases |
container_volume |
7 |
container_issue |
8 |
container_start_page |
e2333 |
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1766342590772281344 |