LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA
The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the l...
Published in: | Siberian journal of oncology |
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Main Authors: | , , , , |
Format: | Article in Journal/Newspaper |
Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2021
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Online Access: | https://doi.org/10.21294/1814-4861-2021-20-4-30-38 https://doaj.org/article/6eff340faa1c44939f000981e3d06c0f |
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ftdoajarticles:oai:doaj.org/article:6eff340faa1c44939f000981e3d06c0f 2023-05-15T17:02:47+02:00 LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA A. A. Mordovskii A. A. Aksarin A. M. Parsadanyan M. D. Ter-Ovanesov P. P. Troyan 2021-08-01T00:00:00Z https://doi.org/10.21294/1814-4861-2021-20-4-30-38 https://doaj.org/article/6eff340faa1c44939f000981e3d06c0f RU rus Russian Academy of Sciences, Tomsk National Research Medical Center https://www.siboncoj.ru/jour/article/view/1859 https://doaj.org/toc/1814-4861 https://doaj.org/toc/2312-3168 1814-4861 2312-3168 doi:10.21294/1814-4861-2021-20-4-30-38 https://doaj.org/article/6eff340faa1c44939f000981e3d06c0f Сибирский онкологический журнал, Vol 20, Iss 4, Pp 30-38 (2021) рак легкого эпидемиология заболеваемость смертность ранняя диагностика загрязнение атмосферного воздуха корреляционный анализ Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 article 2021 ftdoajarticles https://doi.org/10.21294/1814-4861-2021-20-4-30-38 2023-03-19T01:38:07Z The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease. Article in Journal/Newspaper khanty khanty-mansi Mansi Directory of Open Access Journals: DOAJ Articles Siberian journal of oncology 20 4 30 38 |
institution |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
Russian |
topic |
рак легкого эпидемиология заболеваемость смертность ранняя диагностика загрязнение атмосферного воздуха корреляционный анализ Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
spellingShingle |
рак легкого эпидемиология заболеваемость смертность ранняя диагностика загрязнение атмосферного воздуха корреляционный анализ Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 A. A. Mordovskii A. A. Aksarin A. M. Parsadanyan M. D. Ter-Ovanesov P. P. Troyan LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
topic_facet |
рак легкого эпидемиология заболеваемость смертность ранняя диагностика загрязнение атмосферного воздуха корреляционный анализ Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
description |
The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease. |
format |
Article in Journal/Newspaper |
author |
A. A. Mordovskii A. A. Aksarin A. M. Parsadanyan M. D. Ter-Ovanesov P. P. Troyan |
author_facet |
A. A. Mordovskii A. A. Aksarin A. M. Parsadanyan M. D. Ter-Ovanesov P. P. Troyan |
author_sort |
A. A. Mordovskii |
title |
LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
title_short |
LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
title_full |
LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
title_fullStr |
LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
title_full_unstemmed |
LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA |
title_sort |
lung cancer incidence and mortality in the khanty-mansi autonomous okrug – yugra |
publisher |
Russian Academy of Sciences, Tomsk National Research Medical Center |
publishDate |
2021 |
url |
https://doi.org/10.21294/1814-4861-2021-20-4-30-38 https://doaj.org/article/6eff340faa1c44939f000981e3d06c0f |
genre |
khanty khanty-mansi Mansi |
genre_facet |
khanty khanty-mansi Mansi |
op_source |
Сибирский онкологический журнал, Vol 20, Iss 4, Pp 30-38 (2021) |
op_relation |
https://www.siboncoj.ru/jour/article/view/1859 https://doaj.org/toc/1814-4861 https://doaj.org/toc/2312-3168 1814-4861 2312-3168 doi:10.21294/1814-4861-2021-20-4-30-38 https://doaj.org/article/6eff340faa1c44939f000981e3d06c0f |
op_doi |
https://doi.org/10.21294/1814-4861-2021-20-4-30-38 |
container_title |
Siberian journal of oncology |
container_volume |
20 |
container_issue |
4 |
container_start_page |
30 |
op_container_end_page |
38 |
_version_ |
1766056454714818560 |