Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil
INTRODUCTION: A seroepidemiological survey was carried out to evaluate Trypanosoma cruzi infection in an endemic area of the State of Rio Grande do Norte, Brazil, involving rural residents. METHODS: Sixteen municipalities were randomly selected, 15 from the west mesoregion and one from the central,...
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Sociedade Brasileira de Medicina Tropical (SBMT)
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ftdoajarticles:oai:doaj.org/article:6ebf28dd8da24242aa3ce4ee4e47a4bc 2023-05-15T15:09:32+02:00 Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil Carlos Ramon do Nascimento Brito George Harisson Felinto Sampaio Antonia Cláudia Jácome da Câmara Daniela Ferreira Nunes Paulo Roberto Medeiros de Azevedo Egler Chiari Lúcia Maria da Cunha Galvão 2012-06-01T00:00:00Z https://doi.org/10.1590/S0037-86822012000300013 https://doaj.org/article/6ebf28dd8da24242aa3ce4ee4e47a4bc EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000300013&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000300013 https://doaj.org/article/6ebf28dd8da24242aa3ce4ee4e47a4bc Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 3, Pp 346-352 (2012) Trypanosoma cruzi Doença de Chagas Soroprevalência Variáveis epidemiológicas Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles https://doi.org/10.1590/S0037-86822012000300013 2022-12-30T21:27:52Z INTRODUCTION: A seroepidemiological survey was carried out to evaluate Trypanosoma cruzi infection in an endemic area of the State of Rio Grande do Norte, Brazil, involving rural residents. METHODS: Sixteen municipalities were randomly selected, 15 from the west mesoregion and one from the central, with an estimated population of 83,852 individuals. A total of 1,950 blood samples were collected in the west mesoregion and 390 in Caicó. Anti-T. cruzi antibodies were detected using the Chagatest® ELISA HAI-hemagglutination kits and indirect immunofluorescence. As sera presented indeterminate results, TESAcruzi® western blot was performed to confirm reactivity. RESULTS: An estimated seroprevalence of 6.5% was determined for the west mesoregion and 3.3% for Caicó. Seropositivity rises progressively with the age of individuals, up to 40 years in Caicó and up to 50 years in the west mesoregion. Only educational level and knowledge regarding the triatomine were associated with seropositivity. No seroreactive individuals under 18 years of age were identified. CONCLUSIONS: Infection by T. cruzi remains high and is concentrated in municipalities in the central western area of the west mesoregion; however, evidence suggests a decline in vector transmission in this mesoregion and in Caicó. Epidemiological variables appear not to influence seropositivity, with the exception of education and knowledge concerning the triatomine, among seroreactive individuals from the west mesoregion. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 45 3 346 352 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Trypanosoma cruzi Doença de Chagas Soroprevalência Variáveis epidemiológicas Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Trypanosoma cruzi Doença de Chagas Soroprevalência Variáveis epidemiológicas Arctic medicine. Tropical medicine RC955-962 Carlos Ramon do Nascimento Brito George Harisson Felinto Sampaio Antonia Cláudia Jácome da Câmara Daniela Ferreira Nunes Paulo Roberto Medeiros de Azevedo Egler Chiari Lúcia Maria da Cunha Galvão Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
topic_facet |
Trypanosoma cruzi Doença de Chagas Soroprevalência Variáveis epidemiológicas Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: A seroepidemiological survey was carried out to evaluate Trypanosoma cruzi infection in an endemic area of the State of Rio Grande do Norte, Brazil, involving rural residents. METHODS: Sixteen municipalities were randomly selected, 15 from the west mesoregion and one from the central, with an estimated population of 83,852 individuals. A total of 1,950 blood samples were collected in the west mesoregion and 390 in Caicó. Anti-T. cruzi antibodies were detected using the Chagatest® ELISA HAI-hemagglutination kits and indirect immunofluorescence. As sera presented indeterminate results, TESAcruzi® western blot was performed to confirm reactivity. RESULTS: An estimated seroprevalence of 6.5% was determined for the west mesoregion and 3.3% for Caicó. Seropositivity rises progressively with the age of individuals, up to 40 years in Caicó and up to 50 years in the west mesoregion. Only educational level and knowledge regarding the triatomine were associated with seropositivity. No seroreactive individuals under 18 years of age were identified. CONCLUSIONS: Infection by T. cruzi remains high and is concentrated in municipalities in the central western area of the west mesoregion; however, evidence suggests a decline in vector transmission in this mesoregion and in Caicó. Epidemiological variables appear not to influence seropositivity, with the exception of education and knowledge concerning the triatomine, among seroreactive individuals from the west mesoregion. |
format |
Article in Journal/Newspaper |
author |
Carlos Ramon do Nascimento Brito George Harisson Felinto Sampaio Antonia Cláudia Jácome da Câmara Daniela Ferreira Nunes Paulo Roberto Medeiros de Azevedo Egler Chiari Lúcia Maria da Cunha Galvão |
author_facet |
Carlos Ramon do Nascimento Brito George Harisson Felinto Sampaio Antonia Cláudia Jácome da Câmara Daniela Ferreira Nunes Paulo Roberto Medeiros de Azevedo Egler Chiari Lúcia Maria da Cunha Galvão |
author_sort |
Carlos Ramon do Nascimento Brito |
title |
Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
title_short |
Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
title_full |
Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
title_fullStr |
Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
title_full_unstemmed |
Seroepidemiology of Trypanosoma cruzi infection in the semiarid rural zone of the State of Rio Grande do Norte, Brazil |
title_sort |
seroepidemiology of trypanosoma cruzi infection in the semiarid rural zone of the state of rio grande do norte, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2012 |
url |
https://doi.org/10.1590/S0037-86822012000300013 https://doaj.org/article/6ebf28dd8da24242aa3ce4ee4e47a4bc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 45, Iss 3, Pp 346-352 (2012) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000300013&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/S0037-86822012000300013 https://doaj.org/article/6ebf28dd8da24242aa3ce4ee4e47a4bc |
op_doi |
https://doi.org/10.1590/S0037-86822012000300013 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
45 |
container_issue |
3 |
container_start_page |
346 |
op_container_end_page |
352 |
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