Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review.
Patients with dengue fever and comorbidities seem to be at higher risk of developing complications and/or severe dengue compared to healthier individuals. This study systematically reviews the evidence related to comorbidities and dengue. A systematic literature review was performed in five database...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0004284 https://doaj.org/article/6ea7a81264bd4e11b6f7b0fb48152e3f |
id |
ftdoajarticles:oai:doaj.org/article:6ea7a81264bd4e11b6f7b0fb48152e3f |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:6ea7a81264bd4e11b6f7b0fb48152e3f 2023-05-15T15:05:58+02:00 Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. Joao Toledo Leyanna George Eric Martinez Adhara Lazaro Wai Wai Han Giovanini E Coelho Silvia Runge Ranzinger Olaf Horstick 2016-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004284 https://doaj.org/article/6ea7a81264bd4e11b6f7b0fb48152e3f EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4699776?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004284 https://doaj.org/article/6ea7a81264bd4e11b6f7b0fb48152e3f PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004284 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004284 2022-12-31T01:32:11Z Patients with dengue fever and comorbidities seem to be at higher risk of developing complications and/or severe dengue compared to healthier individuals. This study systematically reviews the evidence related to comorbidities and dengue. A systematic literature review was performed in five databases (EMBASE, PUBMED, Global Health, SciELO, Cochrane) and grey literature for full-text articles since its inceptions until October 10, 2015. A total of 230 articles were retrieved. Sixteen studies were analysed after applying all inclusion and exclusion criteria. Seven case control studies and nine retrospective cohort studies showed that comorbidities may contribute to severe dengue, especially 1) cardiovascular disease, 2) stroke, 3) diabetes, 4) respiratory disease and 5) renal disease, as well as old age. However, due to heterogeneity in studies, the real estimate effect of comorbidities as modifiers of dengue severity could not be established. Further research in regions with high prevalence of dengue infection would contribute to a better understanding of the relevance of comorbidities in severe dengue, especially with a standardised protocol, for outcomes, specific comorbidities, study design-best using prospective designs-and sample sizes. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 1 e0004284 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Joao Toledo Leyanna George Eric Martinez Adhara Lazaro Wai Wai Han Giovanini E Coelho Silvia Runge Ranzinger Olaf Horstick Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Patients with dengue fever and comorbidities seem to be at higher risk of developing complications and/or severe dengue compared to healthier individuals. This study systematically reviews the evidence related to comorbidities and dengue. A systematic literature review was performed in five databases (EMBASE, PUBMED, Global Health, SciELO, Cochrane) and grey literature for full-text articles since its inceptions until October 10, 2015. A total of 230 articles were retrieved. Sixteen studies were analysed after applying all inclusion and exclusion criteria. Seven case control studies and nine retrospective cohort studies showed that comorbidities may contribute to severe dengue, especially 1) cardiovascular disease, 2) stroke, 3) diabetes, 4) respiratory disease and 5) renal disease, as well as old age. However, due to heterogeneity in studies, the real estimate effect of comorbidities as modifiers of dengue severity could not be established. Further research in regions with high prevalence of dengue infection would contribute to a better understanding of the relevance of comorbidities in severe dengue, especially with a standardised protocol, for outcomes, specific comorbidities, study design-best using prospective designs-and sample sizes. |
format |
Article in Journal/Newspaper |
author |
Joao Toledo Leyanna George Eric Martinez Adhara Lazaro Wai Wai Han Giovanini E Coelho Silvia Runge Ranzinger Olaf Horstick |
author_facet |
Joao Toledo Leyanna George Eric Martinez Adhara Lazaro Wai Wai Han Giovanini E Coelho Silvia Runge Ranzinger Olaf Horstick |
author_sort |
Joao Toledo |
title |
Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
title_short |
Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
title_full |
Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
title_fullStr |
Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
title_full_unstemmed |
Relevance of Non-communicable Comorbidities for the Development of the Severe Forms of Dengue: A Systematic Literature Review. |
title_sort |
relevance of non-communicable comorbidities for the development of the severe forms of dengue: a systematic literature review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004284 https://doaj.org/article/6ea7a81264bd4e11b6f7b0fb48152e3f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 1, p e0004284 (2016) |
op_relation |
http://europepmc.org/articles/PMC4699776?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004284 https://doaj.org/article/6ea7a81264bd4e11b6f7b0fb48152e3f |
op_doi |
https://doi.org/10.1371/journal.pntd.0004284 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
10 |
container_issue |
1 |
container_start_page |
e0004284 |
_version_ |
1766337644247121920 |