Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes
Introduction: DNA extracted from ancient human bones allows to analyze the genetic makeup of pre-Columbian populations and to determine the dynamics that gave rise to the diversity of contemporary populations. Objective: To determine the genetic diversity of skeletal remains associated with the Temp...
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ftdoajarticles:oai:doaj.org/article:6e7740b6314f451684e91c8ea91b3df2 2023-05-15T15:09:40+02:00 Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes Andrea Casas-Vargas Liza M. Romero William Usaquén Sara Zea Margarita Silva Ignacio Briceño Alberto Gómez José Vicente Rodríguez 2017-12-01T00:00:00Z https://doi.org/10.7705/biomedica.v37i4.3377 https://doaj.org/article/6e7740b6314f451684e91c8ea91b3df2 EN ES eng spa Instituto Nacional de Salud https://www.revistabiomedica.org/index.php/biomedica/article/view/3377 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i4.3377 https://doaj.org/article/6e7740b6314f451684e91c8ea91b3df2 Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 4, Pp 548-560 (2017) DNA mitocondrial amelogenin Y chromosome Colombia Medicine R Arctic medicine. Tropical medicine RC955-962 article 2017 ftdoajarticles https://doi.org/10.7705/biomedica.v37i4.3377 2022-12-30T23:47:58Z Introduction: DNA extracted from ancient human bones allows to analyze the genetic makeup of pre-Columbian populations and to determine the dynamics that gave rise to the diversity of contemporary populations. Objective: To determine the genetic diversity of skeletal remains associated with the Templo del Sol (Sun Temple) and their relationship with other contemporary and ancient communities of America. Materials and methods: We analyzed 13 individuals belonging to the pre-Columbian Muisca Period (IX-XVI centuries AD) from the vicinities of the Templo del Sol (Sun Temple) (Sogamoso, Boyacá) in the eastern Colombian Andes. Mitochondrial DNA was amplified and RFLPs were performed in order to type the four traditional Amerindian haplogroups (A, B, C and D). In addition, autosomal markers including amelogenin and Y-chromosome STRs were amplified. Results: Among the observed mitochondrial lineages, haplogroup A was the most frequent, followed by haplogroups B and C; no evidence of haplogroup D was found. The genetic variation analysis indicated a similar diversity of pre-Columbian Muiscas to that of contemporary populations belonging to the Chibcha linguistic family from Colombia and Central America. Molecular sexing was accomplished and it was compared to osteological data. With only one exception, anthropological and molecular data were consistent. Conclusions: Our results contribute new genetic elements supporting the hypothesis of Central American origin of the Chibcha groups of the Cundiboyacense plateau, and allowed sex typing and kinship evaluations. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Biomédica 37 4 548 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
DNA mitocondrial amelogenin Y chromosome Colombia Medicine R Arctic medicine. Tropical medicine RC955-962 |
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DNA mitocondrial amelogenin Y chromosome Colombia Medicine R Arctic medicine. Tropical medicine RC955-962 Andrea Casas-Vargas Liza M. Romero William Usaquén Sara Zea Margarita Silva Ignacio Briceño Alberto Gómez José Vicente Rodríguez Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
topic_facet |
DNA mitocondrial amelogenin Y chromosome Colombia Medicine R Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: DNA extracted from ancient human bones allows to analyze the genetic makeup of pre-Columbian populations and to determine the dynamics that gave rise to the diversity of contemporary populations. Objective: To determine the genetic diversity of skeletal remains associated with the Templo del Sol (Sun Temple) and their relationship with other contemporary and ancient communities of America. Materials and methods: We analyzed 13 individuals belonging to the pre-Columbian Muisca Period (IX-XVI centuries AD) from the vicinities of the Templo del Sol (Sun Temple) (Sogamoso, Boyacá) in the eastern Colombian Andes. Mitochondrial DNA was amplified and RFLPs were performed in order to type the four traditional Amerindian haplogroups (A, B, C and D). In addition, autosomal markers including amelogenin and Y-chromosome STRs were amplified. Results: Among the observed mitochondrial lineages, haplogroup A was the most frequent, followed by haplogroups B and C; no evidence of haplogroup D was found. The genetic variation analysis indicated a similar diversity of pre-Columbian Muiscas to that of contemporary populations belonging to the Chibcha linguistic family from Colombia and Central America. Molecular sexing was accomplished and it was compared to osteological data. With only one exception, anthropological and molecular data were consistent. Conclusions: Our results contribute new genetic elements supporting the hypothesis of Central American origin of the Chibcha groups of the Cundiboyacense plateau, and allowed sex typing and kinship evaluations. |
format |
Article in Journal/Newspaper |
author |
Andrea Casas-Vargas Liza M. Romero William Usaquén Sara Zea Margarita Silva Ignacio Briceño Alberto Gómez José Vicente Rodríguez |
author_facet |
Andrea Casas-Vargas Liza M. Romero William Usaquén Sara Zea Margarita Silva Ignacio Briceño Alberto Gómez José Vicente Rodríguez |
author_sort |
Andrea Casas-Vargas |
title |
Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
title_short |
Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
title_full |
Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
title_fullStr |
Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
title_full_unstemmed |
Mitochondrial DNA diversity in prehispanic bone remains on the eastern Colombian Andes |
title_sort |
mitochondrial dna diversity in prehispanic bone remains on the eastern colombian andes |
publisher |
Instituto Nacional de Salud |
publishDate |
2017 |
url |
https://doi.org/10.7705/biomedica.v37i4.3377 https://doaj.org/article/6e7740b6314f451684e91c8ea91b3df2 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 4, Pp 548-560 (2017) |
op_relation |
https://www.revistabiomedica.org/index.php/biomedica/article/view/3377 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i4.3377 https://doaj.org/article/6e7740b6314f451684e91c8ea91b3df2 |
op_doi |
https://doi.org/10.7705/biomedica.v37i4.3377 |
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Biomédica |
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37 |
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4 |
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548 |
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1766340817705762816 |