Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa?
OBJECTIVE: To compare the 1999 World Health Organization (WHO) fasting plasma glucose (FPG) criteria and the WHO 2-hour post-challenge glucose (2hPG) criteria during an oral glucose tolerance test (OGTT) in identifying adults in Jamaica with hyperglycemia. As the OGTT is not commonly used in clinica...
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Pan American Health Organization
2004
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ftdoajarticles:oai:doaj.org/article:6de36c8298644f6e985d4fc4629a4327 2023-05-15T15:19:13+02:00 Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? Lincoln A. Sargeant Michael S. Boyne Franklyn I. Bennett Terrence E. Forrester Richard S. Cooper Rainford J. Wilks 2004-07-01T00:00:00Z https://doaj.org/article/6de36c8298644f6e985d4fc4629a4327 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892004000700005 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/6de36c8298644f6e985d4fc4629a4327 Revista Panamericana de Salud Pública, Vol 16, Iss 1, Pp 35-42 (2004) Diabetes mellitus blood glucose glucose intolerance glucose tolerance test mass screening Jamaica Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2004 ftdoajarticles 2022-12-31T11:31:40Z OBJECTIVE: To compare the 1999 World Health Organization (WHO) fasting plasma glucose (FPG) criteria and the WHO 2-hour post-challenge glucose (2hPG) criteria during an oral glucose tolerance test (OGTT) in identifying adults in Jamaica with hyperglycemia. As the OGTT is not commonly used in clinical practice, factors associated with the failure of the FPG criteria to detect persons with impaired 2hPG were investigated. METHODS: A random sample of 2 096 adults, 25-74 years old, living in the town of Spanish Town, Jamaica, was evaluated for diabetes. After excluding 215 individuals for reasons such as missing data, the remaining 1 881 persons were composed of 187 who were previously known to have diabetes and 1 694 who were screened for diabetes with both FPG and 2hPG. RESULTS: The FPG criteria detected 83 cases of diabetes, compared to 72 by the 2hPG criteria. The kappa statistic comparing the two criteria was 0.31 (95% confidence interval: 0.28- 0.34), indicating fair agreement. There were 261 cases of impaired glucose tolerance (IGT) and 92 cases of impaired fasting glucose (IFG). In those 92 with IFG, an OGTT would identify 34 cases of IGT and 14 cases of diabetes. Of those classified as normoglycemic by FPG criteria, 14% of them had IGT or diabetes by 2hPG criteria. The factors predicting the likelihood of nondetection of impaired glucose tolerance or diabetes by FPG were age, body mass index, central obesity, systolic blood pressure, and female sex. By receiver operating characteristic curve analysis, an FPG of 5.1 mmol/L would predict a 2hPG > 7.8 mmol/L. CONCLUSIONS: A few individuals classified as normal on FPG will have IGT or diabetes, and an OGTT will be needed to identify them. The yield of IGT detected by screening in Jamaica can be improved by lowering the threshold for IFG or by using clinical information to identify high-risk individuals. OBJETIVO: Comparar los criterios publicados por la Organización Mundial de la Salud (OMS) en 1999 acerca del uso de la prueba de glucemia en ayunas (PGA) y ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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English Spanish Portuguese |
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Diabetes mellitus blood glucose glucose intolerance glucose tolerance test mass screening Jamaica Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Diabetes mellitus blood glucose glucose intolerance glucose tolerance test mass screening Jamaica Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Lincoln A. Sargeant Michael S. Boyne Franklyn I. Bennett Terrence E. Forrester Richard S. Cooper Rainford J. Wilks Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
topic_facet |
Diabetes mellitus blood glucose glucose intolerance glucose tolerance test mass screening Jamaica Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVE: To compare the 1999 World Health Organization (WHO) fasting plasma glucose (FPG) criteria and the WHO 2-hour post-challenge glucose (2hPG) criteria during an oral glucose tolerance test (OGTT) in identifying adults in Jamaica with hyperglycemia. As the OGTT is not commonly used in clinical practice, factors associated with the failure of the FPG criteria to detect persons with impaired 2hPG were investigated. METHODS: A random sample of 2 096 adults, 25-74 years old, living in the town of Spanish Town, Jamaica, was evaluated for diabetes. After excluding 215 individuals for reasons such as missing data, the remaining 1 881 persons were composed of 187 who were previously known to have diabetes and 1 694 who were screened for diabetes with both FPG and 2hPG. RESULTS: The FPG criteria detected 83 cases of diabetes, compared to 72 by the 2hPG criteria. The kappa statistic comparing the two criteria was 0.31 (95% confidence interval: 0.28- 0.34), indicating fair agreement. There were 261 cases of impaired glucose tolerance (IGT) and 92 cases of impaired fasting glucose (IFG). In those 92 with IFG, an OGTT would identify 34 cases of IGT and 14 cases of diabetes. Of those classified as normoglycemic by FPG criteria, 14% of them had IGT or diabetes by 2hPG criteria. The factors predicting the likelihood of nondetection of impaired glucose tolerance or diabetes by FPG were age, body mass index, central obesity, systolic blood pressure, and female sex. By receiver operating characteristic curve analysis, an FPG of 5.1 mmol/L would predict a 2hPG > 7.8 mmol/L. CONCLUSIONS: A few individuals classified as normal on FPG will have IGT or diabetes, and an OGTT will be needed to identify them. The yield of IGT detected by screening in Jamaica can be improved by lowering the threshold for IFG or by using clinical information to identify high-risk individuals. OBJETIVO: Comparar los criterios publicados por la Organización Mundial de la Salud (OMS) en 1999 acerca del uso de la prueba de glucemia en ayunas (PGA) y ... |
format |
Article in Journal/Newspaper |
author |
Lincoln A. Sargeant Michael S. Boyne Franklyn I. Bennett Terrence E. Forrester Richard S. Cooper Rainford J. Wilks |
author_facet |
Lincoln A. Sargeant Michael S. Boyne Franklyn I. Bennett Terrence E. Forrester Richard S. Cooper Rainford J. Wilks |
author_sort |
Lincoln A. Sargeant |
title |
Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
title_short |
Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
title_full |
Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
title_fullStr |
Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
title_full_unstemmed |
Impaired glucose regulation in adults in Jamaica: who should have the oral glucose tolerance test? Alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
title_sort |
impaired glucose regulation in adults in jamaica: who should have the oral glucose tolerance test? alteraciones del control de la glucemia: ¿a quiénes se les debe hacer la prueba de tolerancia a una dosis oral de glucosa? |
publisher |
Pan American Health Organization |
publishDate |
2004 |
url |
https://doaj.org/article/6de36c8298644f6e985d4fc4629a4327 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 16, Iss 1, Pp 35-42 (2004) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892004000700005 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/6de36c8298644f6e985d4fc4629a4327 |
_version_ |
1766349403977678848 |