Identification of a conserved var gene in different Plasmodium falciparum strains

• Published in: Malaria Journal
• Main Authors: Sandra Dimonte, Ellen I. Bruske, Corinna Enderes, Thomas D. Otto, Louise Turner, Peter Kremsner, Matthias Frank
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2020
• Subjects: Malaria; var genes; Genetic diversity; Microsatellites; Recombination; VSA; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Moa; Pacific
• Online Access: https://doi.org/10.1186/s12936-020-03257-x; https://doaj.org/article/6d73f5c0de4e4f4d8240455540d44f76

Abstract Background The multicopy var gene family of Plasmodium falciparum is of crucial importance for pathogenesis and antigenic variation. So far only var2csa, the var gene responsible for placental malaria, was found to be highly conserved among all P. falciparum strains. Here, a new conserved 3...