The Global Economic and Health Burden of Human Hookworm Infection.
BACKGROUND:Even though human hookworm infection is highly endemic in many countries throughout the world, its global economic and health impact is not well known. Without a better understanding of hookworm's economic burden worldwide, it is difficult for decision makers such as funders, policy...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0004922 https://doaj.org/article/6cec1993deab4d60bff7a9dc7589398c |
id |
ftdoajarticles:oai:doaj.org/article:6cec1993deab4d60bff7a9dc7589398c |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:6cec1993deab4d60bff7a9dc7589398c 2023-05-15T15:09:42+02:00 The Global Economic and Health Burden of Human Hookworm Infection. Sarah M Bartsch Peter J Hotez Lindsey Asti Kristina M Zapf Maria Elena Bottazzi David J Diemert Bruce Y Lee 2016-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004922 https://doaj.org/article/6cec1993deab4d60bff7a9dc7589398c EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5015833?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004922 https://doaj.org/article/6cec1993deab4d60bff7a9dc7589398c PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004922 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004922 2022-12-31T12:07:05Z BACKGROUND:Even though human hookworm infection is highly endemic in many countries throughout the world, its global economic and health impact is not well known. Without a better understanding of hookworm's economic burden worldwide, it is difficult for decision makers such as funders, policy makers, disease control officials, and intervention manufacturers to determine how much time, energy, and resources to invest in hookworm control. METHODOLOGY/PRINCIPLE FINDINGS:We developed a computational simulation model to estimate the economic and health burden of hookworm infection in every country, WHO region, and globally, in 2016 from the societal perspective. Globally, hookworm infection resulted in a total 2,126,280 DALYs using 2004 disability weight estimates and 4,087,803 DALYs using 2010 disability weight estimates (excluding cognitive impairment outcomes). Including cognitive impairment did not significantly increase DALYs worldwide. Total productivity losses varied with the probability of anemia and calculation method used, ranging from $7.5 billion to $138.9 billion annually using gross national income per capita as a proxy for annual wages and ranging from $2.5 billion to $43.9 billion using minimum wage as a proxy for annual wages. CONCLUSION:Even though hookworm is classified as a neglected tropical disease, its economic and health burden exceeded published estimates for a number of diseases that have received comparatively more attention than hookworm such as rotavirus. Additionally, certain large countries that are transitioning to higher income countries such as Brazil and China, still face considerable hookworm burden. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 9 e0004922 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Sarah M Bartsch Peter J Hotez Lindsey Asti Kristina M Zapf Maria Elena Bottazzi David J Diemert Bruce Y Lee The Global Economic and Health Burden of Human Hookworm Infection. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Even though human hookworm infection is highly endemic in many countries throughout the world, its global economic and health impact is not well known. Without a better understanding of hookworm's economic burden worldwide, it is difficult for decision makers such as funders, policy makers, disease control officials, and intervention manufacturers to determine how much time, energy, and resources to invest in hookworm control. METHODOLOGY/PRINCIPLE FINDINGS:We developed a computational simulation model to estimate the economic and health burden of hookworm infection in every country, WHO region, and globally, in 2016 from the societal perspective. Globally, hookworm infection resulted in a total 2,126,280 DALYs using 2004 disability weight estimates and 4,087,803 DALYs using 2010 disability weight estimates (excluding cognitive impairment outcomes). Including cognitive impairment did not significantly increase DALYs worldwide. Total productivity losses varied with the probability of anemia and calculation method used, ranging from $7.5 billion to $138.9 billion annually using gross national income per capita as a proxy for annual wages and ranging from $2.5 billion to $43.9 billion using minimum wage as a proxy for annual wages. CONCLUSION:Even though hookworm is classified as a neglected tropical disease, its economic and health burden exceeded published estimates for a number of diseases that have received comparatively more attention than hookworm such as rotavirus. Additionally, certain large countries that are transitioning to higher income countries such as Brazil and China, still face considerable hookworm burden. |
format |
Article in Journal/Newspaper |
author |
Sarah M Bartsch Peter J Hotez Lindsey Asti Kristina M Zapf Maria Elena Bottazzi David J Diemert Bruce Y Lee |
author_facet |
Sarah M Bartsch Peter J Hotez Lindsey Asti Kristina M Zapf Maria Elena Bottazzi David J Diemert Bruce Y Lee |
author_sort |
Sarah M Bartsch |
title |
The Global Economic and Health Burden of Human Hookworm Infection. |
title_short |
The Global Economic and Health Burden of Human Hookworm Infection. |
title_full |
The Global Economic and Health Burden of Human Hookworm Infection. |
title_fullStr |
The Global Economic and Health Burden of Human Hookworm Infection. |
title_full_unstemmed |
The Global Economic and Health Burden of Human Hookworm Infection. |
title_sort |
global economic and health burden of human hookworm infection. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004922 https://doaj.org/article/6cec1993deab4d60bff7a9dc7589398c |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004922 (2016) |
op_relation |
http://europepmc.org/articles/PMC5015833?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004922 https://doaj.org/article/6cec1993deab4d60bff7a9dc7589398c |
op_doi |
https://doi.org/10.1371/journal.pntd.0004922 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
10 |
container_issue |
9 |
container_start_page |
e0004922 |
_version_ |
1766340831104466944 |