The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966
Low grade inflammation is associated with many noncommunicable diseases. The association between skin diseases in general and systemic inflammation has not previously been studied at the population level. A whole-body investigation on 1,930 adults belonging to Northern Finland Birth Cohort 1966 was...
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Medical Journals Sweden
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ftdoajarticles:oai:doaj.org/article:6ccc521fa68d453d908bd42ad48d5417 2023-05-15T17:42:15+02:00 The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 Suvi-Päivikki Sinikumpu Laura Huilaja Juha Auvinen Jari Jokelainen Katri Puukka Aimo Ruokonen Markku Timonen Kaisa Tasanen 2017-10-01T00:00:00Z https://doi.org/10.2340/00015555-2795 https://doaj.org/article/6ccc521fa68d453d908bd42ad48d5417 EN eng Medical Journals Sweden https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2795 https://doaj.org/toc/0001-5555 https://doaj.org/toc/1651-2057 0001-5555 1651-2057 doi:10.2340/00015555-2795 https://doaj.org/article/6ccc521fa68d453d908bd42ad48d5417 Acta Dermato-Venereologica, Vol 98, Iss 1, Pp 65-69 (2017) atopiceczema epidemiology fungalskininfection lowgradeinflammation rosacea Dermatology RL1-803 article 2017 ftdoajarticles https://doi.org/10.2340/00015555-2795 2022-12-31T15:16:53Z Low grade inflammation is associated with many noncommunicable diseases. The association between skin diseases in general and systemic inflammation has not previously been studied at the population level. A whole-body investigation on 1,930 adults belonging to Northern Finland Birth Cohort 1966 was performed and high sensitive C-reactive protein (CRP) level was measured as a marker of low grade inflammation in order to determine the association between low grade inflammation and skin diseases in an unselected adult population. After adjustment for confounding factors the following skin disorders were associated with low grade inflammation in multinomial logistic regression analysis: atopic eczema (OR 2.2, 95% CI 1.2–3.9), onychomycosis (OR 2.0, 1.2–3.2) and rosacea (OR 1.7, 1.1–2.5). After additionally adjusting for body mass index and systemic diseases, the risks for atopic eczema (OR 2.4, 1.3–4.6) and onychomycosis (OR 1.9, 1.1–3.1) remained statistically significant. In conclusion, low grade inflammation is present in several skin diseases. Article in Journal/Newspaper Northern Finland Directory of Open Access Journals: DOAJ Articles Acta Dermato Venereologica 98 1 65 69 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
atopiceczema epidemiology fungalskininfection lowgradeinflammation rosacea Dermatology RL1-803 |
spellingShingle |
atopiceczema epidemiology fungalskininfection lowgradeinflammation rosacea Dermatology RL1-803 Suvi-Päivikki Sinikumpu Laura Huilaja Juha Auvinen Jari Jokelainen Katri Puukka Aimo Ruokonen Markku Timonen Kaisa Tasanen The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
topic_facet |
atopiceczema epidemiology fungalskininfection lowgradeinflammation rosacea Dermatology RL1-803 |
description |
Low grade inflammation is associated with many noncommunicable diseases. The association between skin diseases in general and systemic inflammation has not previously been studied at the population level. A whole-body investigation on 1,930 adults belonging to Northern Finland Birth Cohort 1966 was performed and high sensitive C-reactive protein (CRP) level was measured as a marker of low grade inflammation in order to determine the association between low grade inflammation and skin diseases in an unselected adult population. After adjustment for confounding factors the following skin disorders were associated with low grade inflammation in multinomial logistic regression analysis: atopic eczema (OR 2.2, 95% CI 1.2–3.9), onychomycosis (OR 2.0, 1.2–3.2) and rosacea (OR 1.7, 1.1–2.5). After additionally adjusting for body mass index and systemic diseases, the risks for atopic eczema (OR 2.4, 1.3–4.6) and onychomycosis (OR 1.9, 1.1–3.1) remained statistically significant. In conclusion, low grade inflammation is present in several skin diseases. |
format |
Article in Journal/Newspaper |
author |
Suvi-Päivikki Sinikumpu Laura Huilaja Juha Auvinen Jari Jokelainen Katri Puukka Aimo Ruokonen Markku Timonen Kaisa Tasanen |
author_facet |
Suvi-Päivikki Sinikumpu Laura Huilaja Juha Auvinen Jari Jokelainen Katri Puukka Aimo Ruokonen Markku Timonen Kaisa Tasanen |
author_sort |
Suvi-Päivikki Sinikumpu |
title |
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
title_short |
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
title_full |
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
title_fullStr |
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
title_full_unstemmed |
The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966 |
title_sort |
association between low grade systemic inflammation and skin diseases: a cross-sectional survey in the northern finland birth cohort 1966 |
publisher |
Medical Journals Sweden |
publishDate |
2017 |
url |
https://doi.org/10.2340/00015555-2795 https://doaj.org/article/6ccc521fa68d453d908bd42ad48d5417 |
genre |
Northern Finland |
genre_facet |
Northern Finland |
op_source |
Acta Dermato-Venereologica, Vol 98, Iss 1, Pp 65-69 (2017) |
op_relation |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2795 https://doaj.org/toc/0001-5555 https://doaj.org/toc/1651-2057 0001-5555 1651-2057 doi:10.2340/00015555-2795 https://doaj.org/article/6ccc521fa68d453d908bd42ad48d5417 |
op_doi |
https://doi.org/10.2340/00015555-2795 |
container_title |
Acta Dermato Venereologica |
container_volume |
98 |
container_issue |
1 |
container_start_page |
65 |
op_container_end_page |
69 |
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1766144098715041792 |