Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses.
Challenges in maintaining high effectiveness of classic vector control in urban areas has renewed the interest in indoor residual spraying (IRS) as a promising approach for Aedes-borne disease prevention. While IRS has many benefits, application time and intrusive indoor applications make its scalab...
Published in: | PLOS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:6b8f334816d84e28855697ff6419f6cf 2023-05-15T15:16:23+02:00 Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. Mike W Dunbar Fabian Correa-Morales Felipe Dzul-Manzanilla Anuar Medina-Barreiro Wilbert Bibiano-Marín Evaristo Morales-Ríos José Vadillo-Sánchez Beatriz López-Monroy Scott A Ritchie Audrey Lenhart Pablo Manrique-Saide Gonzalo M Vazquez-Prokopec 2019-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007203 https://doaj.org/article/6b8f334816d84e28855697ff6419f6cf EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6394901?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007203 https://doaj.org/article/6b8f334816d84e28855697ff6419f6cf PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007203 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007203 2022-12-31T07:27:56Z Challenges in maintaining high effectiveness of classic vector control in urban areas has renewed the interest in indoor residual spraying (IRS) as a promising approach for Aedes-borne disease prevention. While IRS has many benefits, application time and intrusive indoor applications make its scalability in urban areas difficult. Modifying IRS to account for Ae. aegypti resting behavior, named targeted IRS (TIRS, spraying walls below 1.5 m and under furniture) can reduce application time; however, an untested assumption is that modifications to IRS will not negatively impact entomological efficacy. We conducted a comparative experimental study evaluating the residual efficacy of classically-applied IRS (as developed for malaria control) compared to two TIRS application methods using a carbamate insecticide against a pyrethroid-resistant, field-derived Ae. aegypti strain. We performed our study within a novel experimental house setting (n = 9 houses) located in Merida (Mexico), with similar layouts and standardized contents. Classic IRS application (insecticide applied to full walls and under furniture) was compared to: a) TIRS: insecticide applied to walls below 1.5 m and under furniture, and b) Resting Site TIRS (RS-TIRS): insecticide applied only under furniture. Mosquito mortality was measured eight times post-application (out to six months post-application) by releasing 100 Ae. aegypti females /house and collecting live and dead individuals after 24 hrs exposure. Compared to Classic IRS, TIRS and RS-TIRS took less time to apply (31% and 82% reduction, respectively) and used less insecticide (38% and 85% reduction, respectively). Mortality of pyrethroid-resistant Ae. aegypti did not significantly differ among the three IRS application methods up to two months post application, and did not significantly differ between Classic IRS and TIRS up to four months post application. These data illustrate that optimizing IRS to more efficiently target Ae. aegypti can both reduce application time and insecticide volume ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 13 2 e0007203 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Mike W Dunbar Fabian Correa-Morales Felipe Dzul-Manzanilla Anuar Medina-Barreiro Wilbert Bibiano-Marín Evaristo Morales-Ríos José Vadillo-Sánchez Beatriz López-Monroy Scott A Ritchie Audrey Lenhart Pablo Manrique-Saide Gonzalo M Vazquez-Prokopec Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Challenges in maintaining high effectiveness of classic vector control in urban areas has renewed the interest in indoor residual spraying (IRS) as a promising approach for Aedes-borne disease prevention. While IRS has many benefits, application time and intrusive indoor applications make its scalability in urban areas difficult. Modifying IRS to account for Ae. aegypti resting behavior, named targeted IRS (TIRS, spraying walls below 1.5 m and under furniture) can reduce application time; however, an untested assumption is that modifications to IRS will not negatively impact entomological efficacy. We conducted a comparative experimental study evaluating the residual efficacy of classically-applied IRS (as developed for malaria control) compared to two TIRS application methods using a carbamate insecticide against a pyrethroid-resistant, field-derived Ae. aegypti strain. We performed our study within a novel experimental house setting (n = 9 houses) located in Merida (Mexico), with similar layouts and standardized contents. Classic IRS application (insecticide applied to full walls and under furniture) was compared to: a) TIRS: insecticide applied to walls below 1.5 m and under furniture, and b) Resting Site TIRS (RS-TIRS): insecticide applied only under furniture. Mosquito mortality was measured eight times post-application (out to six months post-application) by releasing 100 Ae. aegypti females /house and collecting live and dead individuals after 24 hrs exposure. Compared to Classic IRS, TIRS and RS-TIRS took less time to apply (31% and 82% reduction, respectively) and used less insecticide (38% and 85% reduction, respectively). Mortality of pyrethroid-resistant Ae. aegypti did not significantly differ among the three IRS application methods up to two months post application, and did not significantly differ between Classic IRS and TIRS up to four months post application. These data illustrate that optimizing IRS to more efficiently target Ae. aegypti can both reduce application time and insecticide volume ... |
format |
Article in Journal/Newspaper |
author |
Mike W Dunbar Fabian Correa-Morales Felipe Dzul-Manzanilla Anuar Medina-Barreiro Wilbert Bibiano-Marín Evaristo Morales-Ríos José Vadillo-Sánchez Beatriz López-Monroy Scott A Ritchie Audrey Lenhart Pablo Manrique-Saide Gonzalo M Vazquez-Prokopec |
author_facet |
Mike W Dunbar Fabian Correa-Morales Felipe Dzul-Manzanilla Anuar Medina-Barreiro Wilbert Bibiano-Marín Evaristo Morales-Ríos José Vadillo-Sánchez Beatriz López-Monroy Scott A Ritchie Audrey Lenhart Pablo Manrique-Saide Gonzalo M Vazquez-Prokopec |
author_sort |
Mike W Dunbar |
title |
Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
title_short |
Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
title_full |
Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
title_fullStr |
Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
title_full_unstemmed |
Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses. |
title_sort |
efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant aedes aegypti within experimental houses. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0007203 https://doaj.org/article/6b8f334816d84e28855697ff6419f6cf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007203 (2019) |
op_relation |
http://europepmc.org/articles/PMC6394901?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007203 https://doaj.org/article/6b8f334816d84e28855697ff6419f6cf |
op_doi |
https://doi.org/10.1371/journal.pntd.0007203 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
13 |
container_issue |
2 |
container_start_page |
e0007203 |
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1766346663648034816 |