Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic
Antibiotic resistance (AR) is a growing health concern worldwide and the Arctic represents an understudied region in terms of AR. This study aimed to quantify AR genes (ARGs) from effluent released from a wastewater treatment plant (WWTP) in Iqaluit, Nunavut, Canada, thus creating a baseline referen...
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Canadian Science Publishing
2023
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Online Access: | https://doi.org/10.1139/as-2023-0011 https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7 |
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ftdoajarticles:oai:doaj.org/article:6b738ef495f9405aa5d85718bf46e4f7 2023-08-20T04:02:45+02:00 Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic Madeleine Starks Christina M. Schaefer Kenneth M. Jeffries David Deslauriers Kim Hoang Luong Charles S. Wong Mark L. Hanson Charles W. Knapp 2023-06-01T00:00:00Z https://doi.org/10.1139/as-2023-0011 https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7 EN FR eng fre Canadian Science Publishing https://cdnsciencepub.com/doi/10.1139/as-2023-0011 https://doaj.org/toc/2368-7460 doi:10.1139/as-2023-0011 2368-7460 https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7 Arctic Science (2023) wastewater contaminants antimicrobial resistance food security Environmental sciences GE1-350 Environmental engineering TA170-171 article 2023 ftdoajarticles https://doi.org/10.1139/as-2023-0011 2023-07-30T00:38:13Z Antibiotic resistance (AR) is a growing health concern worldwide and the Arctic represents an understudied region in terms of AR. This study aimed to quantify AR genes (ARGs) from effluent released from a wastewater treatment plant (WWTP) in Iqaluit, Nunavut, Canada, thus creating a baseline reference for future evaluations. Water, sediment, and truncate softshell clam (Mya truncata) tissue samples were compared from the wastewater, the receiving environment of Frobisher Bay, and nearby undisturbed freshwaters. The pharmaceuticals and personal care products (PPCPs) atenolol, carbamazepine, metoprolol, naproxen, sulfapyridine, and trimethoprim were found in the wastewater, but the PPCPs were undetectable in the receiving environment. However, the relative abundances of ARGs were significantly higher in wastewater than in the receiving environment or reference sites. Abundances did not significantly differ in Frobisher Bay compared to undisturbed reference sites. ARGs in clams near the WWTP had similar relative abundances as those from pristine areas. The lack of ARG detection is likely due to Frobisher Bay tides flushing inputs to levels below detection. These data suggest that the WWTP infrastructure does not influence the receiving environment based on the measured parameters; more importantly, further research must elucidate the impact and fate of AR and PPCPs in Arctic communities. Article in Journal/Newspaper Arctic Arctic Frobisher Bay Iqaluit Nunavut Directory of Open Access Journals: DOAJ Articles Arctic Canada Frobisher Bay ENVELOPE(-66.581,-66.581,62.834,62.834) Nunavut Arctic Science |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English French |
topic |
wastewater contaminants antimicrobial resistance food security Environmental sciences GE1-350 Environmental engineering TA170-171 |
spellingShingle |
wastewater contaminants antimicrobial resistance food security Environmental sciences GE1-350 Environmental engineering TA170-171 Madeleine Starks Christina M. Schaefer Kenneth M. Jeffries David Deslauriers Kim Hoang Luong Charles S. Wong Mark L. Hanson Charles W. Knapp Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
topic_facet |
wastewater contaminants antimicrobial resistance food security Environmental sciences GE1-350 Environmental engineering TA170-171 |
description |
Antibiotic resistance (AR) is a growing health concern worldwide and the Arctic represents an understudied region in terms of AR. This study aimed to quantify AR genes (ARGs) from effluent released from a wastewater treatment plant (WWTP) in Iqaluit, Nunavut, Canada, thus creating a baseline reference for future evaluations. Water, sediment, and truncate softshell clam (Mya truncata) tissue samples were compared from the wastewater, the receiving environment of Frobisher Bay, and nearby undisturbed freshwaters. The pharmaceuticals and personal care products (PPCPs) atenolol, carbamazepine, metoprolol, naproxen, sulfapyridine, and trimethoprim were found in the wastewater, but the PPCPs were undetectable in the receiving environment. However, the relative abundances of ARGs were significantly higher in wastewater than in the receiving environment or reference sites. Abundances did not significantly differ in Frobisher Bay compared to undisturbed reference sites. ARGs in clams near the WWTP had similar relative abundances as those from pristine areas. The lack of ARG detection is likely due to Frobisher Bay tides flushing inputs to levels below detection. These data suggest that the WWTP infrastructure does not influence the receiving environment based on the measured parameters; more importantly, further research must elucidate the impact and fate of AR and PPCPs in Arctic communities. |
format |
Article in Journal/Newspaper |
author |
Madeleine Starks Christina M. Schaefer Kenneth M. Jeffries David Deslauriers Kim Hoang Luong Charles S. Wong Mark L. Hanson Charles W. Knapp |
author_facet |
Madeleine Starks Christina M. Schaefer Kenneth M. Jeffries David Deslauriers Kim Hoang Luong Charles S. Wong Mark L. Hanson Charles W. Knapp |
author_sort |
Madeleine Starks |
title |
Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
title_short |
Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
title_full |
Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
title_fullStr |
Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
title_full_unstemmed |
Presence of antibiotic resistance genes in the receiving environment of Iqaluit's wastewater treatment plant in water, sediment, and clams sampled from Frobisher Bay, Nunavut: a preliminary study in the Canadian Arctic |
title_sort |
presence of antibiotic resistance genes in the receiving environment of iqaluit's wastewater treatment plant in water, sediment, and clams sampled from frobisher bay, nunavut: a preliminary study in the canadian arctic |
publisher |
Canadian Science Publishing |
publishDate |
2023 |
url |
https://doi.org/10.1139/as-2023-0011 https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7 |
long_lat |
ENVELOPE(-66.581,-66.581,62.834,62.834) |
geographic |
Arctic Canada Frobisher Bay Nunavut |
geographic_facet |
Arctic Canada Frobisher Bay Nunavut |
genre |
Arctic Arctic Frobisher Bay Iqaluit Nunavut |
genre_facet |
Arctic Arctic Frobisher Bay Iqaluit Nunavut |
op_source |
Arctic Science (2023) |
op_relation |
https://cdnsciencepub.com/doi/10.1139/as-2023-0011 https://doaj.org/toc/2368-7460 doi:10.1139/as-2023-0011 2368-7460 https://doaj.org/article/6b738ef495f9405aa5d85718bf46e4f7 |
op_doi |
https://doi.org/10.1139/as-2023-0011 |
container_title |
Arctic Science |
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1774713361083138048 |