Plasmodium vivax severe imported malaria in two migrants in France
Abstract Background With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary in...
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ftdoajarticles:oai:doaj.org/article:6ae5f92a77f84325ab3de8b3ca1680ac 2023-05-15T15:17:11+02:00 Plasmodium vivax severe imported malaria in two migrants in France Arezki Izri Sandrine Cojean Claire Leblanc Yves Cohen Olivier Bouchaud Rémy Durand 2019-12-01T00:00:00Z https://doi.org/10.1186/s12936-019-3067-5 https://doaj.org/article/6ae5f92a77f84325ab3de8b3ca1680ac EN eng BMC https://doi.org/10.1186/s12936-019-3067-5 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-3067-5 1475-2875 https://doaj.org/article/6ae5f92a77f84325ab3de8b3ca1680ac Malaria Journal, Vol 18, Iss 1, Pp 1-5 (2019) Plasmodium vivax Imported malaria Severe malaria Relapses Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2019 ftdoajarticles https://doi.org/10.1186/s12936-019-3067-5 2022-12-31T15:43:16Z Abstract Background With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary infection but during relapses. Case presentations Patient 1: A 27-year old male, born in Afghanistan and living in France since 2012, was admitted on August 2015 to the Avicenne hospital because of abdominal pain, intense headache, fever and hypotension. The patient was haemodynamically unstable despite 5 L of filling solution. A thin blood film showed P. vivax trophozoites within the red blood cells. To take care of the septic shock, the patient was given rapid fluid resuscitation, norepinephrine (0.5 mg/h), and intravenous artesunate. Nested polymerase chain reactions of the SSUrRNA gene were negative for Plasmodium falciparum but positive for P. vivax. The patient became apyretic in less than 24H and the parasitaemia was negative at the same time. Patient 2: A 24-year old male, born in Pakistan and living in France, was admitted on August 2016 because of fever, abdominal pain, headache, myalgia, and nausea. The last travel of the patient in a malaria endemic area occurred in 2013. A thin blood film showed P. vivax trophozoites within the red blood cells. The patient was treated orally by dihydroartemisinin-piperaquine and recovered rapidly. Nine months later, the patient returned to the hospital with a relapse of P. vivax malaria. The malaria episode was uncomplicated and the patient recovered rapidly. Three months later, the patient came back again with a third episode of P. vivax malaria. Following a rapid haemodynamic deterioration, the patient was transferred to the intensive care unit of the hospital. In all the patient received 10 L of filling solution to manage the septic shock. After 5 days of hospitalization and a specific treatment, the patient was discharged in good clinical conditions. Conclusion ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 18 1 |
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English |
topic |
Plasmodium vivax Imported malaria Severe malaria Relapses Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Plasmodium vivax Imported malaria Severe malaria Relapses Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Arezki Izri Sandrine Cojean Claire Leblanc Yves Cohen Olivier Bouchaud Rémy Durand Plasmodium vivax severe imported malaria in two migrants in France |
topic_facet |
Plasmodium vivax Imported malaria Severe malaria Relapses Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background With less than one severe case per year in average, Plasmodium vivax is very rarely associated with severe imported malaria in France. Two cases of P. vivax severe malaria occurred in patients with no evident co-morbidity. Interestingly, both cases did not occur at the primary infection but during relapses. Case presentations Patient 1: A 27-year old male, born in Afghanistan and living in France since 2012, was admitted on August 2015 to the Avicenne hospital because of abdominal pain, intense headache, fever and hypotension. The patient was haemodynamically unstable despite 5 L of filling solution. A thin blood film showed P. vivax trophozoites within the red blood cells. To take care of the septic shock, the patient was given rapid fluid resuscitation, norepinephrine (0.5 mg/h), and intravenous artesunate. Nested polymerase chain reactions of the SSUrRNA gene were negative for Plasmodium falciparum but positive for P. vivax. The patient became apyretic in less than 24H and the parasitaemia was negative at the same time. Patient 2: A 24-year old male, born in Pakistan and living in France, was admitted on August 2016 because of fever, abdominal pain, headache, myalgia, and nausea. The last travel of the patient in a malaria endemic area occurred in 2013. A thin blood film showed P. vivax trophozoites within the red blood cells. The patient was treated orally by dihydroartemisinin-piperaquine and recovered rapidly. Nine months later, the patient returned to the hospital with a relapse of P. vivax malaria. The malaria episode was uncomplicated and the patient recovered rapidly. Three months later, the patient came back again with a third episode of P. vivax malaria. Following a rapid haemodynamic deterioration, the patient was transferred to the intensive care unit of the hospital. In all the patient received 10 L of filling solution to manage the septic shock. After 5 days of hospitalization and a specific treatment, the patient was discharged in good clinical conditions. Conclusion ... |
format |
Article in Journal/Newspaper |
author |
Arezki Izri Sandrine Cojean Claire Leblanc Yves Cohen Olivier Bouchaud Rémy Durand |
author_facet |
Arezki Izri Sandrine Cojean Claire Leblanc Yves Cohen Olivier Bouchaud Rémy Durand |
author_sort |
Arezki Izri |
title |
Plasmodium vivax severe imported malaria in two migrants in France |
title_short |
Plasmodium vivax severe imported malaria in two migrants in France |
title_full |
Plasmodium vivax severe imported malaria in two migrants in France |
title_fullStr |
Plasmodium vivax severe imported malaria in two migrants in France |
title_full_unstemmed |
Plasmodium vivax severe imported malaria in two migrants in France |
title_sort |
plasmodium vivax severe imported malaria in two migrants in france |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12936-019-3067-5 https://doaj.org/article/6ae5f92a77f84325ab3de8b3ca1680ac |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 18, Iss 1, Pp 1-5 (2019) |
op_relation |
https://doi.org/10.1186/s12936-019-3067-5 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-3067-5 1475-2875 https://doaj.org/article/6ae5f92a77f84325ab3de8b3ca1680ac |
op_doi |
https://doi.org/10.1186/s12936-019-3067-5 |
container_title |
Malaria Journal |
container_volume |
18 |
container_issue |
1 |
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1766347448884658176 |