Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses.
To obtain further insight into geographic distribution of Leishmania species in Peru, a countrywide survey, including central to southern rainforest areas where information on causative parasite species is limited, was performed based on cytochrome b (cyt b) and mannose phosphate isomerase (mpi) gen...
Published in: | PLOS Neglected Tropical Diseases |
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Language: | English |
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2019
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Online Access: | https://doi.org/10.1371/journal.pntd.0007496 https://doaj.org/article/6ad5226f6a804c5cb47f88db7a30c2e1 |
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ftdoajarticles:oai:doaj.org/article:6ad5226f6a804c5cb47f88db7a30c2e1 2024-09-09T19:26:47+00:00 Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. Hirotomo Kato Abraham G Cáceres Chisato Seki Carmen Rosa Silupu García Carlos Holguín Mauricci Salvadora Concepción Castro Martínez Dafne Moreno Paico Josefa Leila Castro Muniz Lucinda Doriz Troyes Rivera Zoila Isabel Villegas Briones Silvia Guerrero Quincho Guísela Lucy Sulca Jayo Edwin Tineo Villafuerte Carlos Manrique de Lara Estrada Fernando Rafael Arias Fredy Santiago Passara Nancy Ruelas Llerena Makoto Kubo Ahmed Tabbabi Daisuke S Yamamoto Yoshihisa Hashiguchi 2019-06-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007496 https://doaj.org/article/6ad5226f6a804c5cb47f88db7a30c2e1 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0007496 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007496 https://doaj.org/article/6ad5226f6a804c5cb47f88db7a30c2e1 PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007496 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007496 2024-08-05T17:48:54Z To obtain further insight into geographic distribution of Leishmania species in Peru, a countrywide survey, including central to southern rainforest areas where information on causative parasite species is limited, was performed based on cytochrome b (cyt b) and mannose phosphate isomerase (mpi) gene analyses. A total of 262 clinical samples were collected from patients suspected of cutaneous leishmaniasis (CL) in 28 provinces of 13 departments, of which 99 samples were impregnated on FTA (Flinders Technology Associates) cards and 163 samples were Giemsa-stained smears. Leishmania species were successfully identified in 83 (83.8%) of FTA-spotted samples and 59 (36.2%) of Giemsa-stained smear samples. Among the 142 samples identified, the most dominant species was Leishmania (Viannia) braziliensis (47.2%), followed by L. (V.) peruviana (26.1%), and others were L. (V.) guyanensis, L. (V.) lainsoni, L. (V.) shawi, a hybrid of L. (V.) braziliensis and L. (V.) peruviana, and Leishmania (Leishmania) amazonensis. Besides the present epidemiological observations, the current study provided the following findings: 1) A hybrid of L. (V.) braziliensis and L. (V.) peruviana is present outside the Department of Huanuco, the only place reported, 2) Many cases of CL due to L. (V.) lainsoni, an uncommon causative species in Peru, were observed, and 3) L. (V.) shawi is widely circulating in southern Amazonian areas in Peru. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Flinders ENVELOPE(-66.667,-66.667,-69.267,-69.267) PLOS Neglected Tropical Diseases 13 6 e0007496 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Hirotomo Kato Abraham G Cáceres Chisato Seki Carmen Rosa Silupu García Carlos Holguín Mauricci Salvadora Concepción Castro Martínez Dafne Moreno Paico Josefa Leila Castro Muniz Lucinda Doriz Troyes Rivera Zoila Isabel Villegas Briones Silvia Guerrero Quincho Guísela Lucy Sulca Jayo Edwin Tineo Villafuerte Carlos Manrique de Lara Estrada Fernando Rafael Arias Fredy Santiago Passara Nancy Ruelas Llerena Makoto Kubo Ahmed Tabbabi Daisuke S Yamamoto Yoshihisa Hashiguchi Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
To obtain further insight into geographic distribution of Leishmania species in Peru, a countrywide survey, including central to southern rainforest areas where information on causative parasite species is limited, was performed based on cytochrome b (cyt b) and mannose phosphate isomerase (mpi) gene analyses. A total of 262 clinical samples were collected from patients suspected of cutaneous leishmaniasis (CL) in 28 provinces of 13 departments, of which 99 samples were impregnated on FTA (Flinders Technology Associates) cards and 163 samples were Giemsa-stained smears. Leishmania species were successfully identified in 83 (83.8%) of FTA-spotted samples and 59 (36.2%) of Giemsa-stained smear samples. Among the 142 samples identified, the most dominant species was Leishmania (Viannia) braziliensis (47.2%), followed by L. (V.) peruviana (26.1%), and others were L. (V.) guyanensis, L. (V.) lainsoni, L. (V.) shawi, a hybrid of L. (V.) braziliensis and L. (V.) peruviana, and Leishmania (Leishmania) amazonensis. Besides the present epidemiological observations, the current study provided the following findings: 1) A hybrid of L. (V.) braziliensis and L. (V.) peruviana is present outside the Department of Huanuco, the only place reported, 2) Many cases of CL due to L. (V.) lainsoni, an uncommon causative species in Peru, were observed, and 3) L. (V.) shawi is widely circulating in southern Amazonian areas in Peru. |
format |
Article in Journal/Newspaper |
author |
Hirotomo Kato Abraham G Cáceres Chisato Seki Carmen Rosa Silupu García Carlos Holguín Mauricci Salvadora Concepción Castro Martínez Dafne Moreno Paico Josefa Leila Castro Muniz Lucinda Doriz Troyes Rivera Zoila Isabel Villegas Briones Silvia Guerrero Quincho Guísela Lucy Sulca Jayo Edwin Tineo Villafuerte Carlos Manrique de Lara Estrada Fernando Rafael Arias Fredy Santiago Passara Nancy Ruelas Llerena Makoto Kubo Ahmed Tabbabi Daisuke S Yamamoto Yoshihisa Hashiguchi |
author_facet |
Hirotomo Kato Abraham G Cáceres Chisato Seki Carmen Rosa Silupu García Carlos Holguín Mauricci Salvadora Concepción Castro Martínez Dafne Moreno Paico Josefa Leila Castro Muniz Lucinda Doriz Troyes Rivera Zoila Isabel Villegas Briones Silvia Guerrero Quincho Guísela Lucy Sulca Jayo Edwin Tineo Villafuerte Carlos Manrique de Lara Estrada Fernando Rafael Arias Fredy Santiago Passara Nancy Ruelas Llerena Makoto Kubo Ahmed Tabbabi Daisuke S Yamamoto Yoshihisa Hashiguchi |
author_sort |
Hirotomo Kato |
title |
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
title_short |
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
title_full |
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
title_fullStr |
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
title_full_unstemmed |
Further insight into the geographic distribution of Leishmania species in Peru by cytochrome b and mannose phosphate isomerase gene analyses. |
title_sort |
further insight into the geographic distribution of leishmania species in peru by cytochrome b and mannose phosphate isomerase gene analyses. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0007496 https://doaj.org/article/6ad5226f6a804c5cb47f88db7a30c2e1 |
long_lat |
ENVELOPE(-66.667,-66.667,-69.267,-69.267) |
geographic |
Arctic Flinders |
geographic_facet |
Arctic Flinders |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007496 (2019) |
op_relation |
https://doi.org/10.1371/journal.pntd.0007496 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007496 https://doaj.org/article/6ad5226f6a804c5cb47f88db7a30c2e1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007496 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
13 |
container_issue |
6 |
container_start_page |
e0007496 |
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1809896331878072320 |