Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae)
Since the number of microorganisms that are resistant to antibiotics has been increasing steadily, the need for combating these pathogens requires new pharmaceutical agents. To produce these substances, new models have been developed in recent decades. In our study, the venom of Agelena labyrinthica...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:6a6bab26a62a45d0990c457af4529310 2023-05-15T15:05:26+02:00 Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) M Benli N Yigit 2008-01-01T00:00:00Z https://doi.org/10.1590/S1678-91992008000400007 https://doaj.org/article/6a6bab26a62a45d0990c457af4529310 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000400007 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000400007 1678-9199 https://doaj.org/article/6a6bab26a62a45d0990c457af4529310 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 4, Pp 641-650 (2008) Agelena labyrinthica venom antimicrobial activity Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2008 ftdoajarticles https://doi.org/10.1590/S1678-91992008000400007 2022-12-31T15:01:02Z Since the number of microorganisms that are resistant to antibiotics has been increasing steadily, the need for combating these pathogens requires new pharmaceutical agents. To produce these substances, new models have been developed in recent decades. In our study, the venom of Agelena labyrinthica (Clerck, 1757) (Araneae: Agelenidae) was tested against ten bacterial strains, specifically, testing 1/100, 1/10 and 1/1 fractions of diluted venom against these bacteria. While the 1/100 dilution was successful in only one of ten bacterial strains, the 1/10 and the 1/1 were effective on six of ten bacterial strains. The most effective results, among these three different concentrations, were observed on Bacillus subtilis. The other five strains that were also sensitive to the dilutions showed similar inhibition zones. Morphological alterations on bacterial cells and comparison with normal cells were accomplished by scanning electron microscopy (SEM). The venom-treated cells, due to their loss of cytoplasm, shrank and presented cell wall depression. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 14 4 641 650 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Agelena labyrinthica venom antimicrobial activity Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Agelena labyrinthica venom antimicrobial activity Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 M Benli N Yigit Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
topic_facet |
Agelena labyrinthica venom antimicrobial activity Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Since the number of microorganisms that are resistant to antibiotics has been increasing steadily, the need for combating these pathogens requires new pharmaceutical agents. To produce these substances, new models have been developed in recent decades. In our study, the venom of Agelena labyrinthica (Clerck, 1757) (Araneae: Agelenidae) was tested against ten bacterial strains, specifically, testing 1/100, 1/10 and 1/1 fractions of diluted venom against these bacteria. While the 1/100 dilution was successful in only one of ten bacterial strains, the 1/10 and the 1/1 were effective on six of ten bacterial strains. The most effective results, among these three different concentrations, were observed on Bacillus subtilis. The other five strains that were also sensitive to the dilutions showed similar inhibition zones. Morphological alterations on bacterial cells and comparison with normal cells were accomplished by scanning electron microscopy (SEM). The venom-treated cells, due to their loss of cytoplasm, shrank and presented cell wall depression. |
format |
Article in Journal/Newspaper |
author |
M Benli N Yigit |
author_facet |
M Benli N Yigit |
author_sort |
M Benli |
title |
Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
title_short |
Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
title_full |
Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
title_fullStr |
Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
title_full_unstemmed |
Antibacterial activity of venom from funnel web spider Agelena labyrinthica (Araneae: Agelenidae) |
title_sort |
antibacterial activity of venom from funnel web spider agelena labyrinthica (araneae: agelenidae) |
publisher |
SciELO |
publishDate |
2008 |
url |
https://doi.org/10.1590/S1678-91992008000400007 https://doaj.org/article/6a6bab26a62a45d0990c457af4529310 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 4, Pp 641-650 (2008) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000400007 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992008000400007 1678-9199 https://doaj.org/article/6a6bab26a62a45d0990c457af4529310 |
op_doi |
https://doi.org/10.1590/S1678-91992008000400007 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
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14 |
container_issue |
4 |
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641 |
op_container_end_page |
650 |
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1766337141632139264 |