Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis.
Several new classes of medications for diabetes have recently become available newer medication classes have been increasing in use. It is unclear how their utilization varied across provinces and how the COVID-19 pandemic may have affected these trends. Our objective was to investigate Canada-wide...
Published in: | PLOS ONE |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2024
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pone.0307451 https://doaj.org/article/6a4784d401ce498aab828cac6db453a0 |
id |
ftdoajarticles:oai:doaj.org/article:6a4784d401ce498aab828cac6db453a0 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:6a4784d401ce498aab828cac6db453a0 2024-09-15T18:20:17+00:00 Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. Jessica Riad Fred Abdelmalek Noah Ivers Mina Tadrous 2024-01-01T00:00:00Z https://doi.org/10.1371/journal.pone.0307451 https://doaj.org/article/6a4784d401ce498aab828cac6db453a0 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pone.0307451 https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0307451 https://doaj.org/article/6a4784d401ce498aab828cac6db453a0 PLoS ONE, Vol 19, Iss 8, p e0307451 (2024) Medicine R Science Q article 2024 ftdoajarticles https://doi.org/10.1371/journal.pone.0307451 2024-08-26T15:21:16Z Several new classes of medications for diabetes have recently become available newer medication classes have been increasing in use. It is unclear how their utilization varied across provinces and how the COVID-19 pandemic may have affected these trends. Our objective was to investigate Canada-wide and province-specific trends in diabetes medication dispensed by drug class over time, while also examining the impact of the COVID-19 pandemic and related restrictions on diabetes medication dispensing. We conducted a repeated cross-sectional analysis study. Data were obtained from IQVIA's CompuScript database for Canada-wide prescription dispensing patterns in primary care from January 2018 to December 2021. Drug classes of interest were biguanides dipeptidyl peptidase 4 inhibitors, sulfonylurea's, insulins, sodium-glucose co-transporter 2 inhibitors, and glucagon-like peptide-1 receptor agonists. We examined trends before and after the onset of the pandemic with special attention to changes during periods of high COVID-19 activity. Most drug classes displayed a stable number of prescriptions each month throughout, except for glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter 2 inhibitors, which demonstrated a consistent pattern of increased dispensing. Sodium-glucose co-transporter inhibitors and glucagon-like peptide-1 receptor agonists exhibited the greatest growth over the examined period, of 7.9% and 5.0% increases, respectively. For sodium-glucose co-transporter 2 inhibitors, Prince Edward Island (4.0%) displayed the greatest growth while Ontario showed the least (2.5%). For glucagon-like peptide-1 receptor analogs, Saskatchewan (11.3%) displayed the greatest growth and Newfoundland the least (4.5%). The pandemic did not impact overall dispensing trends. However, spikes in COVID-19 cases corresponded to changes in dispensing for most drug classes. Important variations across Canada in guideline-recommended medication classes seems to be increasing over time. This is likely due to ... Article in Journal/Newspaper Newfoundland Prince Edward Island Directory of Open Access Journals: DOAJ Articles PLOS ONE 19 8 e0307451 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Medicine R Science Q |
spellingShingle |
Medicine R Science Q Jessica Riad Fred Abdelmalek Noah Ivers Mina Tadrous Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
topic_facet |
Medicine R Science Q |
description |
Several new classes of medications for diabetes have recently become available newer medication classes have been increasing in use. It is unclear how their utilization varied across provinces and how the COVID-19 pandemic may have affected these trends. Our objective was to investigate Canada-wide and province-specific trends in diabetes medication dispensed by drug class over time, while also examining the impact of the COVID-19 pandemic and related restrictions on diabetes medication dispensing. We conducted a repeated cross-sectional analysis study. Data were obtained from IQVIA's CompuScript database for Canada-wide prescription dispensing patterns in primary care from January 2018 to December 2021. Drug classes of interest were biguanides dipeptidyl peptidase 4 inhibitors, sulfonylurea's, insulins, sodium-glucose co-transporter 2 inhibitors, and glucagon-like peptide-1 receptor agonists. We examined trends before and after the onset of the pandemic with special attention to changes during periods of high COVID-19 activity. Most drug classes displayed a stable number of prescriptions each month throughout, except for glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter 2 inhibitors, which demonstrated a consistent pattern of increased dispensing. Sodium-glucose co-transporter inhibitors and glucagon-like peptide-1 receptor agonists exhibited the greatest growth over the examined period, of 7.9% and 5.0% increases, respectively. For sodium-glucose co-transporter 2 inhibitors, Prince Edward Island (4.0%) displayed the greatest growth while Ontario showed the least (2.5%). For glucagon-like peptide-1 receptor analogs, Saskatchewan (11.3%) displayed the greatest growth and Newfoundland the least (4.5%). The pandemic did not impact overall dispensing trends. However, spikes in COVID-19 cases corresponded to changes in dispensing for most drug classes. Important variations across Canada in guideline-recommended medication classes seems to be increasing over time. This is likely due to ... |
format |
Article in Journal/Newspaper |
author |
Jessica Riad Fred Abdelmalek Noah Ivers Mina Tadrous |
author_facet |
Jessica Riad Fred Abdelmalek Noah Ivers Mina Tadrous |
author_sort |
Jessica Riad |
title |
Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
title_short |
Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
title_full |
Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
title_fullStr |
Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
title_full_unstemmed |
Trends in diabetes medication prescribing from 2018 to 2021: A cross-sectional analysis. |
title_sort |
trends in diabetes medication prescribing from 2018 to 2021: a cross-sectional analysis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2024 |
url |
https://doi.org/10.1371/journal.pone.0307451 https://doaj.org/article/6a4784d401ce498aab828cac6db453a0 |
genre |
Newfoundland Prince Edward Island |
genre_facet |
Newfoundland Prince Edward Island |
op_source |
PLoS ONE, Vol 19, Iss 8, p e0307451 (2024) |
op_relation |
https://doi.org/10.1371/journal.pone.0307451 https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0307451 https://doaj.org/article/6a4784d401ce498aab828cac6db453a0 |
op_doi |
https://doi.org/10.1371/journal.pone.0307451 |
container_title |
PLOS ONE |
container_volume |
19 |
container_issue |
8 |
container_start_page |
e0307451 |
_version_ |
1810458661144756224 |