Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional
Viktor Johanson,1 Benedicte Wilson,2 Anna Abrahamsson,3 Constantin Jianu,4 Jan Calissendorff,5 Najme Wall,6 Henning Grønbæk,7 Jon Florholmen,8 Anders Öhberg,9 Dan Granberg101Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden; 2Department of Medical Gastroenterology, Odense Univ...
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ftdoajarticles:oai:doaj.org/article:697daa37d1f24f7a9f5ba84e33763147 2023-05-15T17:39:24+02:00 Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional Johanson V Wilson B Abrahamsson A Jianu C Calissendorff J Wall N Grønbæk H Florholmen J, Öhberg A Granberg D 2012-10-01T00:00:00Z https://doaj.org/article/697daa37d1f24f7a9f5ba84e33763147 EN eng Dove Medical Press http://www.dovepress.com/randomized-crossover-study-in-patients-with-neuroendocrine-tumors-to-a-a11290 https://doaj.org/toc/1177-889X 1177-889X https://doaj.org/article/697daa37d1f24f7a9f5ba84e33763147 Patient Preference and Adherence, Vol 2012, Iss default, Pp 703-710 (2012) Medicine (General) R5-920 article 2012 ftdoajarticles 2022-12-31T03:29:32Z Viktor Johanson,1 Benedicte Wilson,2 Anna Abrahamsson,3 Constantin Jianu,4 Jan Calissendorff,5 Najme Wall,6 Henning Grønbæk,7 Jon Florholmen,8 Anders Öhberg,9 Dan Granberg101Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden; 2Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark; 3Karolinska Institutet, Department of Hepatology, Karolinska University Hospital, Huddinge, Sweden; 4Department of Gastroenterology and Liver Disease, St Olav Hospital, Trondheim, Norway; 5Karolinska Institutet, Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Solna, Sweden; 6Department of Oncology, Linköping University Hospital, Linköping, Sweden; 7Department of Medicine V, Aarhus University Hospital, Aarhus, Denmark; 8Department of Gastroenterology and Nutrition, University Hospital of North Norway, Tromsø, Norway; 9Medical Department, Ipsen AB, Stockholm, Sweden; 10Department of Medical Sciences, Section of Endocrine Oncology, Uppsala University, Uppsala, SwedenBackground: Lanreotide Autogel® is supplied in prefilled syringes. Therefore, it is possible for patients with neuroendocrine tumors to use self-/partner-administered injections. The primary objective of this study was to assess the proportion of patients preferring self/partner injections over injections administered by health care professionals, and to describe the impact of self/partner administration on efficacy, safety, and costs.Methods: Of 62 eligible patients, 26 (42%) patients with neuroendocrine tumors treated with a stable dose of lanreotide Autogel 90 mg or 120 mg every 4 weeks agreed to participate in this Phase IV, international, open-label, crossover study, conducted at hospitals in Sweden, Norway, and Denmark. Patients were randomized to two blocks, starting with administration of lanreotide Autogel by either self/partner or a health care professional. Preference for injections administered by self/partner or health care professionals was measured, as well as efficacy, ... Article in Journal/Newspaper North Norway Tromsø Directory of Open Access Journals: DOAJ Articles Norway Tromsø St. Olav ENVELOPE(14.984,14.984,67.005,67.005) |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Medicine (General) R5-920 |
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Medicine (General) R5-920 Johanson V Wilson B Abrahamsson A Jianu C Calissendorff J Wall N Grønbæk H Florholmen J, Öhberg A Granberg D Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
topic_facet |
Medicine (General) R5-920 |
description |
Viktor Johanson,1 Benedicte Wilson,2 Anna Abrahamsson,3 Constantin Jianu,4 Jan Calissendorff,5 Najme Wall,6 Henning Grønbæk,7 Jon Florholmen,8 Anders Öhberg,9 Dan Granberg101Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden; 2Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark; 3Karolinska Institutet, Department of Hepatology, Karolinska University Hospital, Huddinge, Sweden; 4Department of Gastroenterology and Liver Disease, St Olav Hospital, Trondheim, Norway; 5Karolinska Institutet, Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Solna, Sweden; 6Department of Oncology, Linköping University Hospital, Linköping, Sweden; 7Department of Medicine V, Aarhus University Hospital, Aarhus, Denmark; 8Department of Gastroenterology and Nutrition, University Hospital of North Norway, Tromsø, Norway; 9Medical Department, Ipsen AB, Stockholm, Sweden; 10Department of Medical Sciences, Section of Endocrine Oncology, Uppsala University, Uppsala, SwedenBackground: Lanreotide Autogel® is supplied in prefilled syringes. Therefore, it is possible for patients with neuroendocrine tumors to use self-/partner-administered injections. The primary objective of this study was to assess the proportion of patients preferring self/partner injections over injections administered by health care professionals, and to describe the impact of self/partner administration on efficacy, safety, and costs.Methods: Of 62 eligible patients, 26 (42%) patients with neuroendocrine tumors treated with a stable dose of lanreotide Autogel 90 mg or 120 mg every 4 weeks agreed to participate in this Phase IV, international, open-label, crossover study, conducted at hospitals in Sweden, Norway, and Denmark. Patients were randomized to two blocks, starting with administration of lanreotide Autogel by either self/partner or a health care professional. Preference for injections administered by self/partner or health care professionals was measured, as well as efficacy, ... |
format |
Article in Journal/Newspaper |
author |
Johanson V Wilson B Abrahamsson A Jianu C Calissendorff J Wall N Grønbæk H Florholmen J, Öhberg A Granberg D |
author_facet |
Johanson V Wilson B Abrahamsson A Jianu C Calissendorff J Wall N Grønbæk H Florholmen J, Öhberg A Granberg D |
author_sort |
Johanson V |
title |
Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
title_short |
Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
title_full |
Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
title_fullStr |
Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
title_full_unstemmed |
Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional |
title_sort |
randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide autogel® given by either self/partner or a health care professional |
publisher |
Dove Medical Press |
publishDate |
2012 |
url |
https://doaj.org/article/697daa37d1f24f7a9f5ba84e33763147 |
long_lat |
ENVELOPE(14.984,14.984,67.005,67.005) |
geographic |
Norway Tromsø St. Olav |
geographic_facet |
Norway Tromsø St. Olav |
genre |
North Norway Tromsø |
genre_facet |
North Norway Tromsø |
op_source |
Patient Preference and Adherence, Vol 2012, Iss default, Pp 703-710 (2012) |
op_relation |
http://www.dovepress.com/randomized-crossover-study-in-patients-with-neuroendocrine-tumors-to-a-a11290 https://doaj.org/toc/1177-889X 1177-889X https://doaj.org/article/697daa37d1f24f7a9f5ba84e33763147 |
_version_ |
1766140156233908224 |