Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil
The prevalence and age distribution of Epstein-Barr virus infection varies in different populations and there is little information about the epidemiology of this infection in Brazil. We studied the prevalence of EBV antibodies in a sample of 283 children and adolescents between 1 and 21 years old....
Main Authors: | , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Sociedade Brasileira de Medicina Tropical (SBMT)
2004
|
Subjects: | |
Online Access: | https://doaj.org/article/6940c4bf5205468cb67c75462d1b6b76 |
id |
ftdoajarticles:oai:doaj.org/article:6940c4bf5205468cb67c75462d1b6b76 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:6940c4bf5205468cb67c75462d1b6b76 2023-05-15T15:10:59+02:00 Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil Cecília M. Figueira-Silva Fausto E.L. Pereira 2004-10-01T00:00:00Z https://doaj.org/article/6940c4bf5205468cb67c75462d1b6b76 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000500008&tlng=en https://doaj.org/toc/1678-9849 1678-9849 https://doaj.org/article/6940c4bf5205468cb67c75462d1b6b76 Revista da Sociedade Brasileira de Medicina Tropical, Vol 37, Iss 5, Pp 409-412 (2004) Epstein-Barr virus Infectious mononucleosis EBV antibodies Arctic medicine. Tropical medicine RC955-962 article 2004 ftdoajarticles 2022-12-31T02:47:39Z The prevalence and age distribution of Epstein-Barr virus infection varies in different populations and there is little information about the epidemiology of this infection in Brazil. We studied the prevalence of EBV antibodies in a sample of 283 children and adolescents between 1 and 21 years old. The sample was taken from two neighborhoods in Vitória (capital city of Espirito Santo, Brazil). The São Pedro (SP) neighborhood represented an area with lower socioeconomic status and the Praias (P) neighborhood represented an area with higher SES. Anti-VCA (Virus Capsid Antigen) antibodies were detected by ELISA and anti-EBNA (Epstein-Barr Nuclear Antigen) antibodies were detected by an anti-complement immunofluorescence method, both using commercial kits. The results showed an overall prevalence rates of anti-VCA and anti-EBNA of 71% and 54% respectively. The prevalence for both anti-EBV antibodies was higher and probably the infection occurred earlier in the SP neighborhood. Among the various socioeconomic factors studied only low family income and maternal education level were significantly correlated with a higher frequency of positive serology for anti-VCA. These results demonstrate that there is a high prevalence of EBV antibodies in children and adolescents living in Vitória, that occurs more frequently at a younger age in children from families with low socioeconomic status. In addition, the results demonstrate an intermediate age distribution pattern between those reported in developed and underdeveloped countries. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Epstein-Barr virus Infectious mononucleosis EBV antibodies Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Epstein-Barr virus Infectious mononucleosis EBV antibodies Arctic medicine. Tropical medicine RC955-962 Cecília M. Figueira-Silva Fausto E.L. Pereira Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
topic_facet |
Epstein-Barr virus Infectious mononucleosis EBV antibodies Arctic medicine. Tropical medicine RC955-962 |
description |
The prevalence and age distribution of Epstein-Barr virus infection varies in different populations and there is little information about the epidemiology of this infection in Brazil. We studied the prevalence of EBV antibodies in a sample of 283 children and adolescents between 1 and 21 years old. The sample was taken from two neighborhoods in Vitória (capital city of Espirito Santo, Brazil). The São Pedro (SP) neighborhood represented an area with lower socioeconomic status and the Praias (P) neighborhood represented an area with higher SES. Anti-VCA (Virus Capsid Antigen) antibodies were detected by ELISA and anti-EBNA (Epstein-Barr Nuclear Antigen) antibodies were detected by an anti-complement immunofluorescence method, both using commercial kits. The results showed an overall prevalence rates of anti-VCA and anti-EBNA of 71% and 54% respectively. The prevalence for both anti-EBV antibodies was higher and probably the infection occurred earlier in the SP neighborhood. Among the various socioeconomic factors studied only low family income and maternal education level were significantly correlated with a higher frequency of positive serology for anti-VCA. These results demonstrate that there is a high prevalence of EBV antibodies in children and adolescents living in Vitória, that occurs more frequently at a younger age in children from families with low socioeconomic status. In addition, the results demonstrate an intermediate age distribution pattern between those reported in developed and underdeveloped countries. |
format |
Article in Journal/Newspaper |
author |
Cecília M. Figueira-Silva Fausto E.L. Pereira |
author_facet |
Cecília M. Figueira-Silva Fausto E.L. Pereira |
author_sort |
Cecília M. Figueira-Silva |
title |
Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
title_short |
Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
title_full |
Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
title_fullStr |
Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
title_full_unstemmed |
Prevalence of Epstein-Barr virus antibodies in healthy children and adolescents in Vitória, State of Espírito Santo, Brazil |
title_sort |
prevalence of epstein-barr virus antibodies in healthy children and adolescents in vitória, state of espírito santo, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2004 |
url |
https://doaj.org/article/6940c4bf5205468cb67c75462d1b6b76 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 37, Iss 5, Pp 409-412 (2004) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822004000500008&tlng=en https://doaj.org/toc/1678-9849 1678-9849 https://doaj.org/article/6940c4bf5205468cb67c75462d1b6b76 |
_version_ |
1766341912139137024 |