Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal
Abstract Helminthic infections concomitant with malaria are common in inter-tropical areas. A recent study showed that mice co-infected with Schistosoma mansoni and Plasmodium chabaudi develop higher P. chabaudi parasitaemia and had a higher mortality rate. This important observation deserved to be...
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ftdoajarticles:oai:doaj.org/article:69401c1ec63746aabea36db488fc5c58 2023-05-15T15:04:00+02:00 Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal Diop Mamadou Camara Pape Akiana Jean Mbaye Pape A Le Hesran Jean-Yves Sokhna Cheikh Ly Abdoulaye Druilhe Pierre 2004-11-01T00:00:00Z https://doi.org/10.1186/1475-2875-3-43 https://doaj.org/article/69401c1ec63746aabea36db488fc5c58 EN eng BMC http://www.malariajournal.com/content/3/1/43 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-3-43 1475-2875 https://doaj.org/article/69401c1ec63746aabea36db488fc5c58 Malaria Journal, Vol 3, Iss 1, p 43 (2004) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2004 ftdoajarticles https://doi.org/10.1186/1475-2875-3-43 2022-12-31T02:15:59Z Abstract Helminthic infections concomitant with malaria are common in inter-tropical areas. A recent study showed that mice co-infected with Schistosoma mansoni and Plasmodium chabaudi develop higher P. chabaudi parasitaemia and had a higher mortality rate. This important observation deserved to be further investigated among human populations. Malaria attacks were recorded in 512 children aged 6–15 years living in Richard Toll (Northern Senegal) among whom 336 were infected by S. mansoni , and 175 were not. The incidence rate of malaria attacks was significantly higher among S. mansoni -infected individuals, particularly those carrying the highest worm loads, as compared to uninfected subjects (26.6% versus 16,4 %). In contrast, the rate of malaria attacks was lower, without reaching significance, in medium grade S. mansoni infections. Thus, infection by S. mansoni affects susceptibility to malaria, but this can vary according to the intensity of parasite load. The immunological mechanisms underlying this dual effect need to be further explored. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 3 1 43 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Diop Mamadou Camara Pape Akiana Jean Mbaye Pape A Le Hesran Jean-Yves Sokhna Cheikh Ly Abdoulaye Druilhe Pierre Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Helminthic infections concomitant with malaria are common in inter-tropical areas. A recent study showed that mice co-infected with Schistosoma mansoni and Plasmodium chabaudi develop higher P. chabaudi parasitaemia and had a higher mortality rate. This important observation deserved to be further investigated among human populations. Malaria attacks were recorded in 512 children aged 6–15 years living in Richard Toll (Northern Senegal) among whom 336 were infected by S. mansoni , and 175 were not. The incidence rate of malaria attacks was significantly higher among S. mansoni -infected individuals, particularly those carrying the highest worm loads, as compared to uninfected subjects (26.6% versus 16,4 %). In contrast, the rate of malaria attacks was lower, without reaching significance, in medium grade S. mansoni infections. Thus, infection by S. mansoni affects susceptibility to malaria, but this can vary according to the intensity of parasite load. The immunological mechanisms underlying this dual effect need to be further explored. |
format |
Article in Journal/Newspaper |
author |
Diop Mamadou Camara Pape Akiana Jean Mbaye Pape A Le Hesran Jean-Yves Sokhna Cheikh Ly Abdoulaye Druilhe Pierre |
author_facet |
Diop Mamadou Camara Pape Akiana Jean Mbaye Pape A Le Hesran Jean-Yves Sokhna Cheikh Ly Abdoulaye Druilhe Pierre |
author_sort |
Diop Mamadou |
title |
Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
title_short |
Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
title_full |
Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
title_fullStr |
Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
title_full_unstemmed |
Increase of malaria attacks among children presenting concomitant infection by Schistosoma mansoni in Senegal |
title_sort |
increase of malaria attacks among children presenting concomitant infection by schistosoma mansoni in senegal |
publisher |
BMC |
publishDate |
2004 |
url |
https://doi.org/10.1186/1475-2875-3-43 https://doaj.org/article/69401c1ec63746aabea36db488fc5c58 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 3, Iss 1, p 43 (2004) |
op_relation |
http://www.malariajournal.com/content/3/1/43 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-3-43 1475-2875 https://doaj.org/article/69401c1ec63746aabea36db488fc5c58 |
op_doi |
https://doi.org/10.1186/1475-2875-3-43 |
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Malaria Journal |
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3 |
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1 |
container_start_page |
43 |
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1766335832926453760 |