Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health.
The objective of this study was to develop a method of classifying comorbid conditions that accounts for both the severity and joint effects of the diseases. The Tromsø Study is a cohort study with a longitudinal design utilizing a survey approach with physical examinations in the Tromsø municipalit...
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ftdoajarticles:oai:doaj.org/article:690cef6af9a64f85a1e0aa6312ce9d81 2023-05-15T18:34:20+02:00 Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. Geir Fagerjord Lorem Henrik Schirmer Nina Emaus 2016-01-01T00:00:00Z https://doi.org/10.1371/journal.pone.0148830 https://doaj.org/article/690cef6af9a64f85a1e0aa6312ce9d81 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4746071?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0148830 https://doaj.org/article/690cef6af9a64f85a1e0aa6312ce9d81 PLoS ONE, Vol 11, Iss 2, p e0148830 (2016) Medicine R Science Q article 2016 ftdoajarticles https://doi.org/10.1371/journal.pone.0148830 2023-01-08T01:40:42Z The objective of this study was to develop a method of classifying comorbid conditions that accounts for both the severity and joint effects of the diseases. The Tromsø Study is a cohort study with a longitudinal design utilizing a survey approach with physical examinations in the Tromsø municipality from 1974 to 2008, where in total 40051 subjects participated. We used Tromsø 4 as reference population and the Norwegian Institute of Public Health (FHI) panel as validation population. Ordinal regression was used to assess the effect of comorbid disease on Self-Reported Health (SRH). The model is controlled for interaction between diseases, mental health, age, and gender. The health impact index estimated levels of SRH. The comparison of predicted and observed SRH showed no significant differences. Spearman's correlation showed that increasing levels of comorbidity were related to lower levels of SRH (RS = -0.36, p <.001). The Charlson Comorbidity Index(CCI) was also associated with SRH (r = -.25, p <.001). When focusing on only individuals with a comorbid disease, the relation between SRH and the Health Impact Index (HII) was strengthened (r = -.42, p <.001), while the association between SRH and CCI was attenuated (r = -.14, p <.001). CCI was designed to control for comorbid conditions when survival/mortality is the outcome of interest but is inaccurate when the outcome is SRH. We conclude that HII should be used when SRH is not available, and well-being or quality of survival/life is the outcome of interest. Article in Journal/Newspaper Tromsø Directory of Open Access Journals: DOAJ Articles Tromsø PLOS ONE 11 2 e0148830 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English |
topic |
Medicine R Science Q |
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Medicine R Science Q Geir Fagerjord Lorem Henrik Schirmer Nina Emaus Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
topic_facet |
Medicine R Science Q |
description |
The objective of this study was to develop a method of classifying comorbid conditions that accounts for both the severity and joint effects of the diseases. The Tromsø Study is a cohort study with a longitudinal design utilizing a survey approach with physical examinations in the Tromsø municipality from 1974 to 2008, where in total 40051 subjects participated. We used Tromsø 4 as reference population and the Norwegian Institute of Public Health (FHI) panel as validation population. Ordinal regression was used to assess the effect of comorbid disease on Self-Reported Health (SRH). The model is controlled for interaction between diseases, mental health, age, and gender. The health impact index estimated levels of SRH. The comparison of predicted and observed SRH showed no significant differences. Spearman's correlation showed that increasing levels of comorbidity were related to lower levels of SRH (RS = -0.36, p <.001). The Charlson Comorbidity Index(CCI) was also associated with SRH (r = -.25, p <.001). When focusing on only individuals with a comorbid disease, the relation between SRH and the Health Impact Index (HII) was strengthened (r = -.42, p <.001), while the association between SRH and CCI was attenuated (r = -.14, p <.001). CCI was designed to control for comorbid conditions when survival/mortality is the outcome of interest but is inaccurate when the outcome is SRH. We conclude that HII should be used when SRH is not available, and well-being or quality of survival/life is the outcome of interest. |
format |
Article in Journal/Newspaper |
author |
Geir Fagerjord Lorem Henrik Schirmer Nina Emaus |
author_facet |
Geir Fagerjord Lorem Henrik Schirmer Nina Emaus |
author_sort |
Geir Fagerjord Lorem |
title |
Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
title_short |
Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
title_full |
Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
title_fullStr |
Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
title_full_unstemmed |
Health Impact Index. Development and Validation of a Method for Classifying Comorbid Disease Measured against Self-Reported Health. |
title_sort |
health impact index. development and validation of a method for classifying comorbid disease measured against self-reported health. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pone.0148830 https://doaj.org/article/690cef6af9a64f85a1e0aa6312ce9d81 |
geographic |
Tromsø |
geographic_facet |
Tromsø |
genre |
Tromsø |
genre_facet |
Tromsø |
op_source |
PLoS ONE, Vol 11, Iss 2, p e0148830 (2016) |
op_relation |
http://europepmc.org/articles/PMC4746071?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0148830 https://doaj.org/article/690cef6af9a64f85a1e0aa6312ce9d81 |
op_doi |
https://doi.org/10.1371/journal.pone.0148830 |
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PLOS ONE |
container_volume |
11 |
container_issue |
2 |
container_start_page |
e0148830 |
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