Preparation of monoclonal antibodies against gamma-type phospholipase A2 inhibitors and immunodetection of these proteins in snake blood

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: Jingjing Li, Ying Xiong, Shimin Sun, Lehan Yu, Chunhong Huang
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO 2017
• Subjects: Monoclonal antibody; Phospholipase A2 inhibitor; Epitope prediction; Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic; Keyhole
• Online Access: https://doi.org/10.1186/s40409-017-0128-5; https://doaj.org/article/68668882d3f94a30a2359caa96b217fb

Abstract Background The gamma-type phospholipase A2 inhibitor (PLIγ) is a natural protein commonly found in snake serum, which can neutralize pathophysiological effects of snake venom phospholipases A2. Therefore, this protein is a potential candidate to the development of a novel antivenom. To the...