Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain
To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and North...
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ftdoajarticles:oai:doaj.org/article:683c207488874832bf86121a0295f99b 2023-05-15T15:31:23+02:00 Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain Charlotte M. Bolton Michaël Bekaert Mariann Eilertsen Jon Vidar Helvik Herve Migaud 2021-12-01T00:00:00Z https://doi.org/10.3389/fphys.2021.761109 https://doaj.org/article/683c207488874832bf86121a0295f99b EN eng Frontiers Media S.A. https://www.frontiersin.org/articles/10.3389/fphys.2021.761109/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2021.761109 https://doaj.org/article/683c207488874832bf86121a0295f99b Frontiers in Physiology, Vol 12 (2021) clock genes ohnologs circadian whole-genome duplication rhythmic expression Physiology QP1-981 article 2021 ftdoajarticles https://doi.org/10.3389/fphys.2021.761109 2022-12-31T09:29:10Z To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and Northern pike, appeared to be duplicated. In comparison to the 29 clock genes described in zebrafish, 48 clock genes were discovered in salmonid species. There was also evidence of species-specific reciprocal gene losses conserved to the Oncorhynchus sister clade. From the six period genes identified three were highly significantly rhythmic, and circadian in their expression patterns (per1a.1, per1a.2, per1b) and two was significantly rhythmically expressed (per2a, per2b). The transcriptomic study of juvenile Atlantic salmon (parr) brain tissues confirmed gene identification and revealed that there were 2,864 rhythmically expressed genes (p < 0.001), including 1,215 genes with a circadian expression pattern, of which 11 were clock genes. The majority of circadian expressed genes peaked 2 h before and after daylight. These findings provide a foundation for further research into the function of clock genes circadian rhythmicity and the role of an enriched number of clock genes relating to seasonal driven life history in salmonids. Article in Journal/Newspaper Atlantic salmon Directory of Open Access Journals: DOAJ Articles Frontiers in Physiology 12 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
clock genes ohnologs circadian whole-genome duplication rhythmic expression Physiology QP1-981 |
spellingShingle |
clock genes ohnologs circadian whole-genome duplication rhythmic expression Physiology QP1-981 Charlotte M. Bolton Michaël Bekaert Mariann Eilertsen Jon Vidar Helvik Herve Migaud Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
topic_facet |
clock genes ohnologs circadian whole-genome duplication rhythmic expression Physiology QP1-981 |
description |
To better understand the complexity of clock genes in salmonids, a taxon with an additional whole genome duplication, an analysis was performed to identify and classify gene family members (clock, arntl, period, cryptochrome, nr1d, ror, and csnk1). The majority of clock genes, in zebrafish and Northern pike, appeared to be duplicated. In comparison to the 29 clock genes described in zebrafish, 48 clock genes were discovered in salmonid species. There was also evidence of species-specific reciprocal gene losses conserved to the Oncorhynchus sister clade. From the six period genes identified three were highly significantly rhythmic, and circadian in their expression patterns (per1a.1, per1a.2, per1b) and two was significantly rhythmically expressed (per2a, per2b). The transcriptomic study of juvenile Atlantic salmon (parr) brain tissues confirmed gene identification and revealed that there were 2,864 rhythmically expressed genes (p < 0.001), including 1,215 genes with a circadian expression pattern, of which 11 were clock genes. The majority of circadian expressed genes peaked 2 h before and after daylight. These findings provide a foundation for further research into the function of clock genes circadian rhythmicity and the role of an enriched number of clock genes relating to seasonal driven life history in salmonids. |
format |
Article in Journal/Newspaper |
author |
Charlotte M. Bolton Michaël Bekaert Mariann Eilertsen Jon Vidar Helvik Herve Migaud |
author_facet |
Charlotte M. Bolton Michaël Bekaert Mariann Eilertsen Jon Vidar Helvik Herve Migaud |
author_sort |
Charlotte M. Bolton |
title |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_short |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_full |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_fullStr |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_full_unstemmed |
Rhythmic Clock Gene Expression in Atlantic Salmon Parr Brain |
title_sort |
rhythmic clock gene expression in atlantic salmon parr brain |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doi.org/10.3389/fphys.2021.761109 https://doaj.org/article/683c207488874832bf86121a0295f99b |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Frontiers in Physiology, Vol 12 (2021) |
op_relation |
https://www.frontiersin.org/articles/10.3389/fphys.2021.761109/full https://doaj.org/toc/1664-042X 1664-042X doi:10.3389/fphys.2021.761109 https://doaj.org/article/683c207488874832bf86121a0295f99b |
op_doi |
https://doi.org/10.3389/fphys.2021.761109 |
container_title |
Frontiers in Physiology |
container_volume |
12 |
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1766361879643422720 |