Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms
The protection of the liver as an essential organ in the body against oxidative stress and deleterious compounds has been the subject of recent investigations. Among different compounds, medicinal plants play an important role due to their hepatoprotective effects. Taraxacum officinale or “common da...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2020
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ftdoajarticles:oai:doaj.org/article:67bb8a54837d4d428728f211fb66a9bd 2023-05-15T15:06:16+02:00 Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms Mohaddese Mahboubi Mona Mahboubi 2020-01-01T00:00:00Z https://doi.org/10.4103/2221-1691.273081 https://doaj.org/article/67bb8a54837d4d428728f211fb66a9bd EN eng Wolters Kluwer Medknow Publications http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=1;spage=1;epage=10;aulast=Mahboubi https://doaj.org/toc/2588-9222 2588-9222 doi:10.4103/2221-1691.273081 https://doaj.org/article/67bb8a54837d4d428728f211fb66a9bd Asian Pacific Journal of Tropical Biomedicine, Vol 10, Iss 1, Pp 1-10 (2020) dandelion hepatoprotective effects antioxidant anti-inflammatory Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2020 ftdoajarticles https://doi.org/10.4103/2221-1691.273081 2022-12-31T05:44:42Z The protection of the liver as an essential organ in the body against oxidative stress and deleterious compounds has been the subject of recent investigations. Among different compounds, medicinal plants play an important role due to their hepatoprotective effects. Taraxacum officinale or “common dandelion” is a popular plant that has been traditionally used for its hepatoprotective effects. Currently, there are limited clinical studies on its hepatoprotective effects. The aim of this review article is to evaluate the hepatoprotective effects of dandelion and its mechanism of action. We reviewed literature up to July 2019 on “Taraxacum officinale” or “dandelion” and hepatoprotection. Currently available pharmacological studies indicate that dandelion extracts have hepatoprotective effects against chemical agents due to its antioxidant and anti-inflammatory activities. The anti-inflammatory effects of dandelion, the prebiotic effects of its oligofructans, inhibitory effects against the release of lipopolysaccharides and fasting induced adipose factor, digestive enzymes, and enhancing effects of lipogenesis, reduce lipid accumulation and liver inflammation, which directly or indirectly improve the liver functions. Given emerging evidence on hepatoprotective effects of dandelion, designing large human clinical studies is essential. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 10 1 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
dandelion hepatoprotective effects antioxidant anti-inflammatory Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
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dandelion hepatoprotective effects antioxidant anti-inflammatory Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Mohaddese Mahboubi Mona Mahboubi Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
topic_facet |
dandelion hepatoprotective effects antioxidant anti-inflammatory Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
The protection of the liver as an essential organ in the body against oxidative stress and deleterious compounds has been the subject of recent investigations. Among different compounds, medicinal plants play an important role due to their hepatoprotective effects. Taraxacum officinale or “common dandelion” is a popular plant that has been traditionally used for its hepatoprotective effects. Currently, there are limited clinical studies on its hepatoprotective effects. The aim of this review article is to evaluate the hepatoprotective effects of dandelion and its mechanism of action. We reviewed literature up to July 2019 on “Taraxacum officinale” or “dandelion” and hepatoprotection. Currently available pharmacological studies indicate that dandelion extracts have hepatoprotective effects against chemical agents due to its antioxidant and anti-inflammatory activities. The anti-inflammatory effects of dandelion, the prebiotic effects of its oligofructans, inhibitory effects against the release of lipopolysaccharides and fasting induced adipose factor, digestive enzymes, and enhancing effects of lipogenesis, reduce lipid accumulation and liver inflammation, which directly or indirectly improve the liver functions. Given emerging evidence on hepatoprotective effects of dandelion, designing large human clinical studies is essential. |
format |
Article in Journal/Newspaper |
author |
Mohaddese Mahboubi Mona Mahboubi |
author_facet |
Mohaddese Mahboubi Mona Mahboubi |
author_sort |
Mohaddese Mahboubi |
title |
Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
title_short |
Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
title_full |
Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
title_fullStr |
Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
title_full_unstemmed |
Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms |
title_sort |
hepatoprotection by dandelion (taraxacum officinale) and mechanisms |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2020 |
url |
https://doi.org/10.4103/2221-1691.273081 https://doaj.org/article/67bb8a54837d4d428728f211fb66a9bd |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 10, Iss 1, Pp 1-10 (2020) |
op_relation |
http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=1;spage=1;epage=10;aulast=Mahboubi https://doaj.org/toc/2588-9222 2588-9222 doi:10.4103/2221-1691.273081 https://doaj.org/article/67bb8a54837d4d428728f211fb66a9bd |
op_doi |
https://doi.org/10.4103/2221-1691.273081 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
10 |
container_issue |
1 |
container_start_page |
1 |
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