Malaria among under-five children in Ethiopia: a systematic review and meta-analysis
Abstract Background Globally, malaria is among the leading cause of under-five mortality and morbidity. Despite various malaria elimination strategies being implemented in the last decades, malaria remains a major public health concern, particularly in tropical and sub-tropical regions. Furthermore,...
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ftdoajarticles:oai:doaj.org/article:67088b2617fc48a18c1d23a2e1d9f32f 2023-05-15T15:14:26+02:00 Malaria among under-five children in Ethiopia: a systematic review and meta-analysis Gebeyaw Biset Abay Woday Tadess Kirubel Dagnaw Tegegne Lehulu Tilahun Natnael Atnafu 2022-11-01T00:00:00Z https://doi.org/10.1186/s12936-022-04370-9 https://doaj.org/article/67088b2617fc48a18c1d23a2e1d9f32f EN eng BMC https://doi.org/10.1186/s12936-022-04370-9 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04370-9 1475-2875 https://doaj.org/article/67088b2617fc48a18c1d23a2e1d9f32f Malaria Journal, Vol 21, Iss 1, Pp 1-12 (2022) Under-five children Malaria Systematic review Meta-analysis Ethiopia Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2022 ftdoajarticles https://doi.org/10.1186/s12936-022-04370-9 2022-12-30T20:12:46Z Abstract Background Globally, malaria is among the leading cause of under-five mortality and morbidity. Despite various malaria elimination strategies being implemented in the last decades, malaria remains a major public health concern, particularly in tropical and sub-tropical regions. Furthermore, there have been limited and inconclusive studies in Ethiopia to generate information for action towards malaria in under-five children. Additionally, there is a considerable disparity between the results of the existing studies. Therefore, the pooled estimate from this study will provide a more conclusive result to take evidence-based interventional measures against under-five malaria. Methods The protocol of this review is registered at PROSPERO with registration number CRD42020157886. All appropriate databases and grey literature were searched to find relevant articles. Studies reporting the prevalence or risk factors of malaria among under-five children were included. The quality of each study was assessed using the Newcastle–Ottawa Quality Assessment Scale (NOS). Data was extracted using Microsoft Excel 2016 and analysis was done using STATA 16.0 statistical software. The pooled prevalence and its associated factors of malaria were determined using a random effect model. Heterogeneity between studies was assessed using the Cochrane Q-test statistics and I2 test. Furthermore, publication bias was checked by the visual inspection of the funnel plot and using Egger’s and Begg’s statistical tests. Results Twelve studies with 34,842 under-five children were included. The pooled prevalence of under-five malaria was 22.03% (95% CI 12.25%, 31.80%). Lack of insecticide-treated mosquito net utilization (AOR: 5.67, 95% CI 3.6, 7.74), poor knowledge of child caretakers towards malaria transmission (AOR: 2.79, 95% CI 1.70, 3.89), and living near mosquito breeding sites (AOR: 5.05, 95% CI 2.92, 7.19) were risk factors of under-five malaria. Conclusion More than one in five children aged under five years were infected with ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 21 1 |
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ftdoajarticles |
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English |
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Under-five children Malaria Systematic review Meta-analysis Ethiopia Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Under-five children Malaria Systematic review Meta-analysis Ethiopia Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Gebeyaw Biset Abay Woday Tadess Kirubel Dagnaw Tegegne Lehulu Tilahun Natnael Atnafu Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
topic_facet |
Under-five children Malaria Systematic review Meta-analysis Ethiopia Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Globally, malaria is among the leading cause of under-five mortality and morbidity. Despite various malaria elimination strategies being implemented in the last decades, malaria remains a major public health concern, particularly in tropical and sub-tropical regions. Furthermore, there have been limited and inconclusive studies in Ethiopia to generate information for action towards malaria in under-five children. Additionally, there is a considerable disparity between the results of the existing studies. Therefore, the pooled estimate from this study will provide a more conclusive result to take evidence-based interventional measures against under-five malaria. Methods The protocol of this review is registered at PROSPERO with registration number CRD42020157886. All appropriate databases and grey literature were searched to find relevant articles. Studies reporting the prevalence or risk factors of malaria among under-five children were included. The quality of each study was assessed using the Newcastle–Ottawa Quality Assessment Scale (NOS). Data was extracted using Microsoft Excel 2016 and analysis was done using STATA 16.0 statistical software. The pooled prevalence and its associated factors of malaria were determined using a random effect model. Heterogeneity between studies was assessed using the Cochrane Q-test statistics and I2 test. Furthermore, publication bias was checked by the visual inspection of the funnel plot and using Egger’s and Begg’s statistical tests. Results Twelve studies with 34,842 under-five children were included. The pooled prevalence of under-five malaria was 22.03% (95% CI 12.25%, 31.80%). Lack of insecticide-treated mosquito net utilization (AOR: 5.67, 95% CI 3.6, 7.74), poor knowledge of child caretakers towards malaria transmission (AOR: 2.79, 95% CI 1.70, 3.89), and living near mosquito breeding sites (AOR: 5.05, 95% CI 2.92, 7.19) were risk factors of under-five malaria. Conclusion More than one in five children aged under five years were infected with ... |
format |
Article in Journal/Newspaper |
author |
Gebeyaw Biset Abay Woday Tadess Kirubel Dagnaw Tegegne Lehulu Tilahun Natnael Atnafu |
author_facet |
Gebeyaw Biset Abay Woday Tadess Kirubel Dagnaw Tegegne Lehulu Tilahun Natnael Atnafu |
author_sort |
Gebeyaw Biset |
title |
Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
title_short |
Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
title_full |
Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
title_fullStr |
Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
title_full_unstemmed |
Malaria among under-five children in Ethiopia: a systematic review and meta-analysis |
title_sort |
malaria among under-five children in ethiopia: a systematic review and meta-analysis |
publisher |
BMC |
publishDate |
2022 |
url |
https://doi.org/10.1186/s12936-022-04370-9 https://doaj.org/article/67088b2617fc48a18c1d23a2e1d9f32f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 21, Iss 1, Pp 1-12 (2022) |
op_relation |
https://doi.org/10.1186/s12936-022-04370-9 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-022-04370-9 1475-2875 https://doaj.org/article/67088b2617fc48a18c1d23a2e1d9f32f |
op_doi |
https://doi.org/10.1186/s12936-022-04370-9 |
container_title |
Malaria Journal |
container_volume |
21 |
container_issue |
1 |
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1766344892096708608 |