A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program
ObjectiveDue to a tender process in Iceland, all patients on Humira® were switched nationwide to its biosimilar Imraldi® in March 2019. The study aimed to explore the patient's perspective of the Humira® and Imraldi® injection devices.MethodsA standard telephone interview was carried out among...
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ftdoajarticles:oai:doaj.org/article:6638c416c9544571ab32334ba7fb5632 2023-05-15T16:51:51+02:00 A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program Kristin Karlsdottir Anna I. Gunnarsdottir Gerdur Grondal Thorvardur J. Love Elinborg Stefansdottir Loa G. Davidsdottir Ragna H. Thorleifsdottir Bjorn Gudbjornsson 2022-01-01T00:00:00Z https://doi.org/10.3389/fmed.2022.799494 https://doaj.org/article/6638c416c9544571ab32334ba7fb5632 EN eng Frontiers Media S.A. https://www.frontiersin.org/articles/10.3389/fmed.2022.799494/full https://doaj.org/toc/2296-858X 2296-858X doi:10.3389/fmed.2022.799494 https://doaj.org/article/6638c416c9544571ab32334ba7fb5632 Frontiers in Medicine, Vol 9 (2022) adalimumab Humira Imraldi injection devices medicine administration at home Medicine (General) R5-920 article 2022 ftdoajarticles https://doi.org/10.3389/fmed.2022.799494 2022-12-31T04:11:03Z ObjectiveDue to a tender process in Iceland, all patients on Humira® were switched nationwide to its biosimilar Imraldi® in March 2019. The study aimed to explore the patient's perspective of the Humira® and Imraldi® injection devices.MethodsA standard telephone interview was carried out among patients with inflammatory arthritis, inflammatory bowel disease and psoriasis, who underwent this nationwide switching program a few months earlier.ResultsThe response rate was 84.5% (n = 198). The average age was 50.8 years, and 53.5% were female. The patients self-administered the drugs in 96% of the cases. The majority (90.5%) stated that they received individualized instruction on using the Humira® pen, compared to 18.2% who accepted instruction in the case of the Imraldi® pen. Almost half (46.6%) of the patients found it more difficult to use the Imraldi® pen than the Humira® pen, while only 12.5% found the Imraldi® pen easier to use. Firstly, these differences were due to more painful insertion of the needle (62.2%) and secondly, due to the experience, the injection process was different (63.0%).ConclusionPatients with inflammatory disorders who have been treated regularly with adalimumab preferred the Humira® injection device over the Imraldi® device, according to our results. After all, these injection devices' structure and content are not the same, although both contain the same active ingredient, i.e. adalimumab. Our results highlight the importance of thorough information, not only with an information letter but also with the possibilities for individualized introduction in planning switching to biosimilars. Article in Journal/Newspaper Iceland Directory of Open Access Journals: DOAJ Articles The Needle ENVELOPE(-64.047,-64.047,63.267,63.267) Frontiers in Medicine 9 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
adalimumab Humira Imraldi injection devices medicine administration at home Medicine (General) R5-920 |
spellingShingle |
adalimumab Humira Imraldi injection devices medicine administration at home Medicine (General) R5-920 Kristin Karlsdottir Anna I. Gunnarsdottir Gerdur Grondal Thorvardur J. Love Elinborg Stefansdottir Loa G. Davidsdottir Ragna H. Thorleifsdottir Bjorn Gudbjornsson A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
topic_facet |
adalimumab Humira Imraldi injection devices medicine administration at home Medicine (General) R5-920 |
description |
ObjectiveDue to a tender process in Iceland, all patients on Humira® were switched nationwide to its biosimilar Imraldi® in March 2019. The study aimed to explore the patient's perspective of the Humira® and Imraldi® injection devices.MethodsA standard telephone interview was carried out among patients with inflammatory arthritis, inflammatory bowel disease and psoriasis, who underwent this nationwide switching program a few months earlier.ResultsThe response rate was 84.5% (n = 198). The average age was 50.8 years, and 53.5% were female. The patients self-administered the drugs in 96% of the cases. The majority (90.5%) stated that they received individualized instruction on using the Humira® pen, compared to 18.2% who accepted instruction in the case of the Imraldi® pen. Almost half (46.6%) of the patients found it more difficult to use the Imraldi® pen than the Humira® pen, while only 12.5% found the Imraldi® pen easier to use. Firstly, these differences were due to more painful insertion of the needle (62.2%) and secondly, due to the experience, the injection process was different (63.0%).ConclusionPatients with inflammatory disorders who have been treated regularly with adalimumab preferred the Humira® injection device over the Imraldi® device, according to our results. After all, these injection devices' structure and content are not the same, although both contain the same active ingredient, i.e. adalimumab. Our results highlight the importance of thorough information, not only with an information letter but also with the possibilities for individualized introduction in planning switching to biosimilars. |
format |
Article in Journal/Newspaper |
author |
Kristin Karlsdottir Anna I. Gunnarsdottir Gerdur Grondal Thorvardur J. Love Elinborg Stefansdottir Loa G. Davidsdottir Ragna H. Thorleifsdottir Bjorn Gudbjornsson |
author_facet |
Kristin Karlsdottir Anna I. Gunnarsdottir Gerdur Grondal Thorvardur J. Love Elinborg Stefansdottir Loa G. Davidsdottir Ragna H. Thorleifsdottir Bjorn Gudbjornsson |
author_sort |
Kristin Karlsdottir |
title |
A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
title_short |
A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
title_full |
A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
title_fullStr |
A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
title_full_unstemmed |
A Patients' Perspective Towards the Injection Devices for Humira® and Imraldi® in a Nationwide Switching Program |
title_sort |
patients' perspective towards the injection devices for humira® and imraldi® in a nationwide switching program |
publisher |
Frontiers Media S.A. |
publishDate |
2022 |
url |
https://doi.org/10.3389/fmed.2022.799494 https://doaj.org/article/6638c416c9544571ab32334ba7fb5632 |
long_lat |
ENVELOPE(-64.047,-64.047,63.267,63.267) |
geographic |
The Needle |
geographic_facet |
The Needle |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Frontiers in Medicine, Vol 9 (2022) |
op_relation |
https://www.frontiersin.org/articles/10.3389/fmed.2022.799494/full https://doaj.org/toc/2296-858X 2296-858X doi:10.3389/fmed.2022.799494 https://doaj.org/article/6638c416c9544571ab32334ba7fb5632 |
op_doi |
https://doi.org/10.3389/fmed.2022.799494 |
container_title |
Frontiers in Medicine |
container_volume |
9 |
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1766041967116943360 |