Hepatitis B: Prevalence and occult infection in HIV-infected patients

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Samira Julien Calux, Vanessa Cristina Martins Silva, Adriana Parise Compri, Marcílio Figueiredo Lemos, Ana Paula de Torres Santos, Isabel Takano Oba, Maria Cássia J. Mendes-Correa, Regina Célia Moreira
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2020
• Subjects: Prevalence; Occult hepatitis B infection; HBV; HIV; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0533-2018; https://doaj.org/article/66132b0fae9140209d78d4baa782faac

Abstract INTRODUCTION: HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection. METHODS: All samples were tested for serology markers and using qPCR. RESULTS: This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI. CONCLUSIONS: We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.