Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study
Abstract Background Tuberculosis (TB) remains a top global health problem and its transmission rate among contacts is higher when they are cohabiting with a person who is sputum smear-positive. Our study aimed to describe the prevalence of TB among student contacts in the university and determine fa...
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ftdoajarticles:oai:doaj.org/article:65c475f7bc2046688eb2c45f292f8bde 2023-05-15T15:15:51+02:00 Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study Teresia Maina Annie Willetts Moses Ngari Abdullahi Osman 2021-12-01T00:00:00Z https://doi.org/10.1186/s41182-021-00391-3 https://doaj.org/article/65c475f7bc2046688eb2c45f292f8bde EN eng BMC https://doi.org/10.1186/s41182-021-00391-3 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-021-00391-3 1349-4147 https://doaj.org/article/65c475f7bc2046688eb2c45f292f8bde Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-11 (2021) Contact investigation University students Index cases Clinical TB GeneXpert Tuberculosis Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.1186/s41182-021-00391-3 2022-12-31T15:13:45Z Abstract Background Tuberculosis (TB) remains a top global health problem and its transmission rate among contacts is higher when they are cohabiting with a person who is sputum smear-positive. Our study aimed to describe the prevalence of TB among student contacts in the university and determine factors associated with TB transmission. Methods We performed a cross-sectional study with an active contact case finding approach among students receiving treatment at Kilifi County Hospital from January 2016 to December 2017. The study was conducted in a public university in Kilifi County, a rural area within the resource-limited context of Kenya. The study population included students attending the university and identified as sharing accommodation or off-campus hostels, or a close social contact to an index case. The index case was defined as a fellow university student diagnosed with TB at the Kilifi County Hospital during the study period. Contacts were traced and tested for TB using GeneXpert. Results Among the 57 eligible index students identified, 51 (89%) agreed to participate. A total of 156 student contacts were recruited, screened and provided a sputum sample. The prevalence of TB (GeneXpert test positive/clinical diagnosis) among all contacts was 8.3% (95% CI 4.5–14%). Among the 8.3% testing positive 3.2% (95% CI 1.0–7.3%) were positive for GeneXpert only. Sharing a bed with an index case was the only factor significantly associated with TB infection. No other demographic or clinical factor was associated with TB infection. Conclusion Our study identified a high level of TB transmission among university students who had contact with the index cases. The study justifies further research to explore the genetic sequence and magnitude of TB transmission among students in overcrowded university in resource limited contexts. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Medicine and Health 49 1 |
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Directory of Open Access Journals: DOAJ Articles |
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Contact investigation University students Index cases Clinical TB GeneXpert Tuberculosis Arctic medicine. Tropical medicine RC955-962 |
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Contact investigation University students Index cases Clinical TB GeneXpert Tuberculosis Arctic medicine. Tropical medicine RC955-962 Teresia Maina Annie Willetts Moses Ngari Abdullahi Osman Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
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Contact investigation University students Index cases Clinical TB GeneXpert Tuberculosis Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Tuberculosis (TB) remains a top global health problem and its transmission rate among contacts is higher when they are cohabiting with a person who is sputum smear-positive. Our study aimed to describe the prevalence of TB among student contacts in the university and determine factors associated with TB transmission. Methods We performed a cross-sectional study with an active contact case finding approach among students receiving treatment at Kilifi County Hospital from January 2016 to December 2017. The study was conducted in a public university in Kilifi County, a rural area within the resource-limited context of Kenya. The study population included students attending the university and identified as sharing accommodation or off-campus hostels, or a close social contact to an index case. The index case was defined as a fellow university student diagnosed with TB at the Kilifi County Hospital during the study period. Contacts were traced and tested for TB using GeneXpert. Results Among the 57 eligible index students identified, 51 (89%) agreed to participate. A total of 156 student contacts were recruited, screened and provided a sputum sample. The prevalence of TB (GeneXpert test positive/clinical diagnosis) among all contacts was 8.3% (95% CI 4.5–14%). Among the 8.3% testing positive 3.2% (95% CI 1.0–7.3%) were positive for GeneXpert only. Sharing a bed with an index case was the only factor significantly associated with TB infection. No other demographic or clinical factor was associated with TB infection. Conclusion Our study identified a high level of TB transmission among university students who had contact with the index cases. The study justifies further research to explore the genetic sequence and magnitude of TB transmission among students in overcrowded university in resource limited contexts. |
format |
Article in Journal/Newspaper |
author |
Teresia Maina Annie Willetts Moses Ngari Abdullahi Osman |
author_facet |
Teresia Maina Annie Willetts Moses Ngari Abdullahi Osman |
author_sort |
Teresia Maina |
title |
Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
title_short |
Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
title_full |
Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
title_fullStr |
Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
title_full_unstemmed |
Tuberculosis infection among youths in overcrowded university hostels in Kenya: a cross-sectional study |
title_sort |
tuberculosis infection among youths in overcrowded university hostels in kenya: a cross-sectional study |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s41182-021-00391-3 https://doaj.org/article/65c475f7bc2046688eb2c45f292f8bde |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Medicine and Health, Vol 49, Iss 1, Pp 1-11 (2021) |
op_relation |
https://doi.org/10.1186/s41182-021-00391-3 https://doaj.org/toc/1349-4147 doi:10.1186/s41182-021-00391-3 1349-4147 https://doaj.org/article/65c475f7bc2046688eb2c45f292f8bde |
op_doi |
https://doi.org/10.1186/s41182-021-00391-3 |
container_title |
Tropical Medicine and Health |
container_volume |
49 |
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1 |
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1766346190224359424 |