Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil
Abstract Background Brazilian malaria control programmes successfully reduced the incidence and mortality rates from 2005 to 2016. Since 2017, increased malaria has been reported across the Amazon. Few field studies focus on the primary malaria vector in high to moderate endemic areas, Nyssorhynchus...
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ftdoajarticles:oai:doaj.org/article:64fa9c27ba2042568493872973e3061f 2023-05-15T15:17:12+02:00 Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil Maria Anice M. Sallum Jan E. Conn Eduardo S. Bergo Gabriel Z. Laporta Leonardo S. M. Chaves Sara A. Bickersmith Tatiane M. P. de Oliveira Elder Augusto G. Figueira Gilberto Moresco Lêuda Olívêr Claudio J. Struchiner Laith Yakob Eduardo Massad 2019-04-01T00:00:00Z https://doi.org/10.1186/s12936-019-2753-7 https://doaj.org/article/64fa9c27ba2042568493872973e3061f EN eng BMC http://link.springer.com/article/10.1186/s12936-019-2753-7 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2753-7 1475-2875 https://doaj.org/article/64fa9c27ba2042568493872973e3061f Malaria Journal, Vol 18, Iss 1, Pp 1-15 (2019) Epidemiology Transmission Malaria metrics Rural settlements Brazilian Amazon Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2019 ftdoajarticles https://doi.org/10.1186/s12936-019-2753-7 2022-12-31T04:03:14Z Abstract Background Brazilian malaria control programmes successfully reduced the incidence and mortality rates from 2005 to 2016. Since 2017, increased malaria has been reported across the Amazon. Few field studies focus on the primary malaria vector in high to moderate endemic areas, Nyssorhynchus darlingi, as the key entomological component of malaria risk, and on the metrics of Plasmodium vivax propagation in Amazonian rural communities. Methods Human landing catch collections were carried out in 36 houses of 26 communities in five municipalities in the Brazilian states of Acre, Amazonas and Rondônia states, with API (> 30). In addition, data on the number of locally acquired symptomatic infections were employed in mathematical modelling analyses carried out to determine Ny. darlingi vector competence and vectorial capacity to P. vivax; and to calculate the basic reproduction number for P. vivax. Results Entomological indices and malaria metrics ranged among localities: prevalence of P. vivax infection in Ny. darlingi, from 0.243% in Mâncio Lima, Acre to 3.96% in Machadinho D’Oeste, Rondônia; daily human-biting rate per person from 23 ± 1.18 in Cruzeiro do Sul, Acre, to 66 ± 2.41 in Lábrea, Amazonas; vector competence from 0.00456 in São Gabriel da Cachoeira, Amazonas to 0.04764 in Mâncio Lima, Acre; vectorial capacity from 0.0836 in Mâncio Lima, to 1.5 in Machadinho D’Oeste. The estimated R 0 for P. vivax (PvR 0) was 3.3 in Mâncio Lima, 7.0 in Lábrea, 16.8 in Cruzeiro do Sul, 55.5 in São Gabriel da Cachoeira, and 58.7 in Machadinho D’Oeste. Correlation between P. vivax prevalence in Ny. darlingi and vector competence was non-linear whereas association between prevalence of P. vivax in mosquitoes, vectorial capacity and R 0 was linear and positive. Conclusions In spite of low vector competence of Ny. darlingi to P. vivax, parasite propagation in the human population is enhanced by the high human-biting rate, and relatively high vectorial capacity. The high PvR 0 values suggest hyperendemicity in ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 18 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Epidemiology Transmission Malaria metrics Rural settlements Brazilian Amazon Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Epidemiology Transmission Malaria metrics Rural settlements Brazilian Amazon Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Maria Anice M. Sallum Jan E. Conn Eduardo S. Bergo Gabriel Z. Laporta Leonardo S. M. Chaves Sara A. Bickersmith Tatiane M. P. de Oliveira Elder Augusto G. Figueira Gilberto Moresco Lêuda Olívêr Claudio J. Struchiner Laith Yakob Eduardo Massad Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
topic_facet |
Epidemiology Transmission Malaria metrics Rural settlements Brazilian Amazon Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Brazilian malaria control programmes successfully reduced the incidence and mortality rates from 2005 to 2016. Since 2017, increased malaria has been reported across the Amazon. Few field studies focus on the primary malaria vector in high to moderate endemic areas, Nyssorhynchus darlingi, as the key entomological component of malaria risk, and on the metrics of Plasmodium vivax propagation in Amazonian rural communities. Methods Human landing catch collections were carried out in 36 houses of 26 communities in five municipalities in the Brazilian states of Acre, Amazonas and Rondônia states, with API (> 30). In addition, data on the number of locally acquired symptomatic infections were employed in mathematical modelling analyses carried out to determine Ny. darlingi vector competence and vectorial capacity to P. vivax; and to calculate the basic reproduction number for P. vivax. Results Entomological indices and malaria metrics ranged among localities: prevalence of P. vivax infection in Ny. darlingi, from 0.243% in Mâncio Lima, Acre to 3.96% in Machadinho D’Oeste, Rondônia; daily human-biting rate per person from 23 ± 1.18 in Cruzeiro do Sul, Acre, to 66 ± 2.41 in Lábrea, Amazonas; vector competence from 0.00456 in São Gabriel da Cachoeira, Amazonas to 0.04764 in Mâncio Lima, Acre; vectorial capacity from 0.0836 in Mâncio Lima, to 1.5 in Machadinho D’Oeste. The estimated R 0 for P. vivax (PvR 0) was 3.3 in Mâncio Lima, 7.0 in Lábrea, 16.8 in Cruzeiro do Sul, 55.5 in São Gabriel da Cachoeira, and 58.7 in Machadinho D’Oeste. Correlation between P. vivax prevalence in Ny. darlingi and vector competence was non-linear whereas association between prevalence of P. vivax in mosquitoes, vectorial capacity and R 0 was linear and positive. Conclusions In spite of low vector competence of Ny. darlingi to P. vivax, parasite propagation in the human population is enhanced by the high human-biting rate, and relatively high vectorial capacity. The high PvR 0 values suggest hyperendemicity in ... |
format |
Article in Journal/Newspaper |
author |
Maria Anice M. Sallum Jan E. Conn Eduardo S. Bergo Gabriel Z. Laporta Leonardo S. M. Chaves Sara A. Bickersmith Tatiane M. P. de Oliveira Elder Augusto G. Figueira Gilberto Moresco Lêuda Olívêr Claudio J. Struchiner Laith Yakob Eduardo Massad |
author_facet |
Maria Anice M. Sallum Jan E. Conn Eduardo S. Bergo Gabriel Z. Laporta Leonardo S. M. Chaves Sara A. Bickersmith Tatiane M. P. de Oliveira Elder Augusto G. Figueira Gilberto Moresco Lêuda Olívêr Claudio J. Struchiner Laith Yakob Eduardo Massad |
author_sort |
Maria Anice M. Sallum |
title |
Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
title_short |
Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
title_full |
Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
title_fullStr |
Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
title_full_unstemmed |
Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil |
title_sort |
vector competence, vectorial capacity of nyssorhynchus darlingi and the basic reproduction number of plasmodium vivax in agricultural settlements in the amazonian region of brazil |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12936-019-2753-7 https://doaj.org/article/64fa9c27ba2042568493872973e3061f |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 18, Iss 1, Pp 1-15 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s12936-019-2753-7 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2753-7 1475-2875 https://doaj.org/article/64fa9c27ba2042568493872973e3061f |
op_doi |
https://doi.org/10.1186/s12936-019-2753-7 |
container_title |
Malaria Journal |
container_volume |
18 |
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1 |
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1766347464358494208 |